Madrona Venture Group — 2025 Investments

EdgeRunner develops domain-specific Small Language Models (SLMs) that run locally on-device, isolated from external networks, to address data privacy, latency, and cost concerns.

AI & Machine LearningCybersecurityDefense TechEnterprise SoftwareBellevue, US

CMColton Malkerson(Co-founder)inTXTyler Xuan Saltsman(Founder)in

BoardMMMatt McIlwain(Director)Dan Scholnick(Director)

Board seatMSMatthew S. McIlwain· per SEC Form D

Co-investorsALAlumni VenturesTRTrinity Ventures

Impart provides runtime security controls for API and application protection, operating inline in production environments to detect and block attacks in real time.

AI & Machine LearningCybersecurityEnterprise SoftwareSaaSSan Francisco, US

JDJonathan DiVincenzo(Founder)inMHMarc Harrison(Founder)inBJBrian Joe(Founder)in

Board seatKMKaran Mehandru· per SEC Form D

Co-investors8-8-Bit CapitalALAlumni VenturesAVAviso VenturesBABascom VenturesCRCRV (Charles River Ventures)INIndie.vc+1 more

Yoodli is an AI-powered platform that provides interactive roleplay scenarios to help users improve their communication skills and public speaking confidence.

AI & Machine LearningEdTechSaaSSales TechSeattle, US

VPVarun Puri(Founder)inEsha J.(Chief Customer Officer, Co-founder)EJEsha Joshi(Founder)inVarun P.(CEO, Co-founder)

BoardNHNeeraj Hablani(Director)in

Board seatPEPatrick Ennis· per SEC Form D

Co-investorsNONotable CapitalALAllen Institute for AI (AI2) IncubatorALAllen Institute for Artificial Intelligence Incubator (AI2)ASAscend Venture CapitalJ4J4 VenturesMAMadrona Venture Labs+4 more

Charta provides AI-powered chart review and autonomous coding software for healthcare revenue cycle management, helping providers increase revenue and reduce billing denials by analyzing patient charts for coding accuracy and completeness.

AI & Machine LearningDigital HealthHealthtechSan Francisco, US

SMScott Morris(Founder)inJLJustin Liu(Founder)inJustin Liu Scott Morris(Founder)

BoardAaref Hilialy(Director)

Co-investorsBABain Capital VenturesRERefract VenturesSOSouth Park CommonsSVSV Angel

Clarify builds a modern CRM platform that consolidates customer data from multiple sources, automates workflows, and provides insights to drive business growth.

AI & Machine LearningEnterprise SoftwareSaaSSales TechDover, US

PTPatrick Thompson(Founder)inOHOndrej Hrebicek(Founder)inAHAustin Hay(Founder)inPPPranav Priyush(CEO)

BoardMGMatt Garratt(Director)inZBZachary Bratun-Glennon(Director)in

Co-investorsASAscend Venture CapitalESEssence Venture CapitalFIFikaGRGradient VenturesINInvariantes FundRERecall Capital+6 more

Fyxer is an email productivity tool that integrates with Gmail and Outlook to help teams manage communications and reduce time spent in email.

AI & Machine LearningEnterprise SoftwareFuture of WorkSaaS

Archie Hollingsworth(Founder)Matt Ffrench(Founder)Matthew Ffrench(Founder)Richard Hollingsworth(Founder)

Co-investors2020VCCOCompanion M Gmb HTETenacity Capital GlobalTRTranspose Platform ManagementFRFreigeist CapitalHFHF0+1 more

GrowthX provides AI-driven service workflows that structure knowledge work as versioned, observable, and continuously improved processes.

AI & Machine LearningEnterprise SoftwareMarketing TechSaaSSan Francisco, US

MSMarcel Santilli(Founder)inDLDaniel Lopes(Founder)inNadia Santilli(Executive Officer, Director)Marcel Santili(Founder)

Co-investorsHUHubSpot VenturesPRPROOF

Hearvana is developing acoustic intelligence technology aimed at enhancing listening capabilities for both humans and machines.

AI & Machine LearningDeep TechHardware

SGShyam Gollakota(Founder)inMalek Itani(Founder)inTuochao Chen(Founder)

Co-investorsALAllen Institute for AI (AI2) IncubatorASAscend Venture CapitalJ4J4 VenturesPOPoint72 VenturesSCSCB 10XAIAI2 Incubator+6 more

Inductive Bio builds AI and machine learning software to accelerate drug discovery for pharmaceutical and biotech researchers, combining computational chemistry with expertise in translating complex drug programs from preclinical to clinical stages.

AI & Machine LearningBiotechDeep TechBrooklyn, US

JHJosh Haimson(Executive Officer, Director)inBBBen Birnbaum(Ph.D.)inATAlexander Taylor(Ph.D.)in

BoardRGRohan Ganesh(Director)in

Co-investorsALAlleyCorpANAndreessen HorowitzCOCoalition OperatorsENEnsemble LabsLULux CapitalOBObvious Ventures+5 more

Juno is a travel platform that handles business trip booking and management, including flights, hotels, rescheduling, and expense submission.

FintechSaaSTravel & Hospitality

DTDevon Tivona(Founder)in

Co-investorsAVAvid Ventures

Observe provides observability software that helps engineers troubleshoot distributed applications, consolidating logs, metrics, and traces into a single platform built on Snowflake.

AI & Machine LearningCloud ComputingDeveloper ToolsEnterprise SoftwarePalo Alto, US

Qi Jin(Executive Officer)inKBKeith Butler(Executive Officer)inJBJeremy Burton(Executive Officer, Director)inBCBrian Campbell(Executive Officer)inChristine Dorrion(Executive Officer)inJacob Leverich(Founder)in

Co-investorsSUSutter Hill VenturesALAlumni VenturesARArtisanal VenturesBABasecamp FundEVEvolution Equity PartnersHUHuman Capital+8 more

OpenHands is an open-source platform for building and deploying AI coding agents that can be deployed locally or across an organization.

AI & Machine LearningCloud ComputingDeveloper ToolsEnterprise Software

RBRobert Brennan(Founder)inGNGraham Neubig(Founder)inXWXingyao Wang(Founder)inBSBen Solari(CRO)in

Co-investors64645 VenturesALAlumni VenturesBEBetaworksFUFujitsu VenturesMEMenlo VenturesPIPillar VC+3 more

StackBlitz provides a browser-based development environment for creating and launching web applications, with code execution happening entirely within the user's browser using WebAssembly technology.

Cloud ComputingDeveloper ToolsEnterprise SoftwareSan Francisco, US

ESEric Simons(Founder)inAlbert Pai(Founder)inABAlexander Berger(Chief Operating Officer)inBABryan Adams(Vice President of Sales)inMitchell Wright(Head of Growth Marketing and Data)inHCHyllarie Colyer(Head of People)in

Co-investors51515 VenturesCOConvictionEMEmergence Capital PartnersGRGreylock PartnersGVGV (Google Ventures)INInsight Partners+5 more

Statsig provides a feature management and experimentation platform that enables teams to control software releases through gradual rollouts and A/B testing.

Developer ToolsSaaSBellevue, US

Vijaye Raji(Founder)

Co-investorsICICONIQMAMadrona Venture LabsSCScribble VenturesSESequoia CapitalSUSunflower Capital Management FundANAndreessen Horowitz+3 more

Synthesize develops generative AI models that simulate human tissue responses to drugs and diseases for clinical trial design.

AI & Machine LearningBiotechDigital Health

RBRobert Bradley, PhDinJLJeff Leek, PhDinAWAlice Walsh, PhDinGKGregory Koytiger, PhDinJeff Leek(Founder)Robert Bradley(Founder)

Co-investorsAIAI2 IncubatorINInner Loop CapitalSASahsen Ventures

WisdomAI offers an agentic AI analytics platform that builds and governs enterprise business context — metrics, definitions, permissions, and business logic — to deliver validated, accurate answers across chat, dashboards, agents, and embedded analytics.

AI & Machine LearningData & InfrastructureEnterprise SoftwareSan Francisco, US

Guilherme Menezes(Founder)inKCKapil Chhabra(Founder)inSMSoham Mazumdar(Founder)inSPSharvanath Pathak(Founder)in

Co-investorsCOCoatue ManagementGRGreatPoint VenturesGTGTM CapitalKLKleiner PerkinsNVNVIDIALALatitude Capital+3 more