LIONHEART VENTURES — Full Portfolio
30 tracked investments · listed companies and verified rows first
Piramidal bridges in-vivo and in-silico intelligence for neuroscience research and clinical applications.
AI & Machine LearningBiotechHealthtechMedical DevicesNew York City, US
Dimitris Fotis Sakellariou(CEO)inKris Pahuja(CPO)inSahil Zubair(Founding Eng)Kyriacos Xanthos(Founding Eng)Yaqub Alwan(Founding Eng)
Co-investorsY CombinatorAdverb Venturesfutureland venturesGaingelsGeek VenturesRitual Capital+11 more
2AB BioscienceS develops first-in-class small molecule therapeutics targeting the 5-HT2A receptor for ophthalmology and central nervous system disorders.
BiotechDeep TechDigital HealthEdTechHealthtechMedical DevicesSanta Monica, US
Alex Speiser(Co-Founder & Chief Executive Officer)inCharles Nichols, PhD(Co-Founder & Chief Science Officer)David Nichols, PhD(Co-Founder & Head of Chemistry)Tim Foster, PhD(Co-Founder & Head of Translational Discovery)
BoardGopal Das(Director)
Co-investorsGaingelsPalo Santo VCTabula Rasa VenturesWhat If Ventures
Academia.edu is a commercial San Francisco platform where researchers share, discover and publish academic papers.
San Francisco, US
Richard Price(Founder)in
BoardBijan Sibet(Director)Ben Ling(Director)inAnthony Duffy(Director)
Co-investorsLocalGlobeSDVTeamworthy VenturesTrue Ventures20VCAlumni Ventures+25 more
Anthropic is an AI safety research company that builds reliable, interpretable, and steerable AI systems.
AI & Machine LearningDeep TechDeveloper ToolsEnterprise SoftwareSan Francisco, US
Dario Amodei(Founder)inDaniela Amodei(Founder)inTom Brown(Founder)inJack Clark(Founder)inJared Kaplan(Founder)inChris Olah(Founder)in
Co-investors3Comma Capital7BC Venture Capital7GC & CoA.Capital VenturesAccelAkka+151 more
Beam is a shared micromobility operator providing electric scooter services across Asia Pacific cities, committed to climate neutrality and Vision Zero safety standards through technology and rider education programs.
Climate TechMobility & TransportationSingapore, SG
Deb Gangopadhyay(Founder)inAlan Jiang(Founder)inAlan Jiang Deb Gangopadhyay(Founder)
Co-investorsAppWorks VenturesArbor VenturesGobi PartnersIndex VenturesK2 GlobalPartech Ventures+7 more
Bodhi is a mobile app that connects users in India with verified astrologers, tarot readers, and numerologists for online consultations via chat or call.
ConsumerMarketplacesWellness & Fitness
Co-investorsUpsparks Capital
Calm is a mental health app offering guided meditations, sleep stories, soundscapes, and stress-relief tools designed to help users manage anxiety, improve sleep, and build healthy habits for overall wellness.
HealthtechMental HealthWellness & FitnessMiami, US
Alex Tew(Founder)inMichael Acton Smith(Founder)inDavid Ko(CEO)
Co-investorsAcumen AmericaBrighter CapitalCherubic VenturesConnect VenturesElefundEQUIAM+25 more
Carbon Crusher uses lignin-based materials to recycle existing road surfaces into carbon-negative replacements, removing approximately 1.5 tonnes of CO2 per 100 feet of road.
Advanced ManufacturingCleantechClimate TechConstruction TechOslo, NO
Haakon Brunell(Founder)inHans Arne Flåto(Founder)inKristoffer Roil(Founder)in
Co-investors10xvaluepartnersCollaborative FundGaingelsLowercarbon CapitalMetaplanetY Combinator+4 more
Charm Industrial converts agricultural residues into bio-oil and injects it underground to remove carbon from the atmosphere at scale.
AgTechCleantechClimate Tech
Shaun Meehan(Founder)inPeter Reinhardt(Founder)inKelly Hering(Founder)Kevin Meissner(Founder)
Co-investorsAENUAzolla VenturesBreyer CapitalCollaborative FundCongruent VenturesGeneral Catalyst+10 more
Clerkenwell Health operates specialized clinical trial sites focused on neuropsychiatric and CNS conditions, including psychedelic-assisted therapy research and trials for depression, anxiety, dementia, and neurodegenerative disorders.
BiotechDigital HealthHealthtechMedical DevicesMental HealthLondon, GB
Dr Simon G.D. Ruffell(Principal Investigator & Sub-Investigator)Dr Paul Morrison(Principal Investigator)Dr Henry Fisher(CSO)Tom McDonald(CEO)Sam Lewis(CFO)George McBride(CCO)
Co-investorsExceptional VenturesMoonstone Venture Capital
Cognigenics is developing iRNAi, a non-invasive intranasal RNA interference platform that delivers programmable RNA therapeutics directly to targeted brain circuits, bypassing the blood-brain barrier to modulate mood, memory, and cognition.
BiotechDeep TechDigital HealthEagle, US
John Mee(Mr. Mee is a promoter, director and officer of the company.)J.L. Mee(Founder)inBarry Linder(Executive Officer, Director, Promoter)Dean Radin(Executive Officer, Director, Promoter)
World leader in drone-based restoration of degraded land
Matthew Ritchie(Founder)inLauren Fletcher(Founder)Susan Graham(Founder)
Co-investorsAt One VenturesFOUNDER.orgLowercarbon CapitalSystemiq CapitalVentureSouqZouk Capital+5 more
Dimensions Retreats operates therapeutic retreat centers combining neuroscientific research and evidence-based somatic therapy with luxury accommodations in natural settings, focusing on mental health and well-being.
HealthtechMental HealthTravel & HospitalityWellness & FitnessKingston, CA
Chris(Founder and CEO)
Heart Aerospace develops electric regional aircraft for commercial airline operators.
Advanced ManufacturingCleantechClimate TechHardwareSpace TechLos Angeles, US
Anders Forslund(CEO)inKlara Forslund(Founder)Bob Criner(Electric Aircraft Propulsion System Engineer)in
Co-investorsBreakthrough Energy Ventures2am VCAlumni VenturesCastor VenturesKoru CapitalLowercarbon Capital+15 more
Journey Clinical provides ketamine-assisted psychotherapy (KAP) for depression, anxiety, and PTSD, partnering patients with licensed therapists and medical teams while coordinating with major insurance providers.
Digital HealthMedical DevicesMental Health
Jonathan Sabbagh(Founder)inMyriam Barthes(Founder)in
Co-investorsAble PartnersAlleyCorpCoalition OperatorsFifty YearsFJ LabsGaingels+9 more
Psychedelic therapies for addiction.
BiotechSan Francisco, US
Jeeshan Chowdhury(Executive Officer, Director, Promoter)in
BoardSam Altman(Director)inKrishna Kantheti(Director)
Co-investorsMBX CapitalAPOLLO PROJECTSUprising
Lucid Computing builds hardware-encrypted compute clusters with verifiable AI audit trails for enterprises and institutions requiring confidentiality and regulatory compliance.
AI & Machine LearningCloud ComputingCybersecurity
Kristian Rönn(Founder)in
Co-investorsJuniper Ventures Management, Llc
Mindstate Design Labs is a clinical-stage drug development company that uses AI to map the biological basis of emotion and cognition, synthesizing psychedelic phenomenology and biochemical data to design pharmaceutical compounds that induce specific therapeutic emotional and cognitive states for mental health treatment.
AI & Machine LearningBiotechHealthtechMental HealthSan Francisco, US
Dillan DiNardo(CEO)inTom Ray(Founder)inTegan Johnson(Director of Operations)
BoardRand Hindi(Director)in
Co-investorsARA NEA Ventures (Brand: Dmz.Xyz)Blast.ClubEmpath VenturesGaingelsImmeasurableInitialized Capital+14 more
NeuroBionics develops soft, flexible neural interface technologies for neuromodulation applications.
BiotechDeep TechHealthtechMedical DevicesSomerville, US
MJ Antonini(Founder, CEO)inNicki Driscoll(Founder, CTO)Polina Anikeeva(Founder)inNicolette Driscoll(Founder)in
Co-investorsDevice of Tomorrow CapitalDolby Family VenturesEmpath VenturesFuture VenturesGreyMatterMana Ventures+4 more
Nuanced provides a desktop application where AI agents assist software developers by converting preliminary concepts into detailed specifications and maintaining involvement throughout the build process.
AI & Machine LearningConsumerDeveloper ToolsSan Francisco, US
Ayman Nadeem(CEO)inDylan John Drover
Co-investorsAlumni VenturesEight CapitalSterling RoadY CombinatorKleiner PerkinsMaven Ventures+2 more
Pelago is a virtual clinic that partners with employers and health plans to provide substance use disorder treatment and management services.
Digital HealthHealthtechNew York City, US
Yusuf Sherwani(CEO)inSarim Siddiqui(Head of Product)inMaroof Ahmed(Founder)inMaroof AhmedinDr Ashish Mandavia MD(EMEA Commercial Director)inIngrid Kessler(Chief People Officer)
Co-investorsAAF Management Ltd.AtomicoCade VenturesGreyMatterKinnevikKreos Capital+16 more
Reconnect Labs develops precision neuropsychiatry approaches to treat sleep, anxiety, and addiction disorders, drawing on clinical drug development and psychiatric research.
BiotechDigital HealthHealthtechMental Health
Michael Kometer(Board Chairman & Co-founder)in
Reprompt builds a digital replica of Earth using AI and location technology.
AI & Machine LearningData & InfrastructureDeveloper ToolsEnterprise SoftwareSan Francisco, US
Lukas Martinelli(Founder)inRob Balian(Founder)inWendy Kyle(Head of Recruiting)
Co-investorsMaiora Rebel VenturesRebel FundRitual CapitalY CombinatorGopher US VentureRecursion Ventures+1 more
Shiok Meats grows shrimp and other seafood through cellular agriculture, cultivating animal tissue in laboratories rather than harvesting from wild or farmed sources.
BiotechClimate TechFoodTechHealthtechSingapore, SG
Ling Ka Yi(Founder)inSandhya Sriram(CEO)in
Co-investorsBig Idea VenturesEntrepreneur FirstSustainable Food VenturesVegInvestY CombinatorAera VC+24 more
Softmax builds AI systems based on organic alignment principles—the concept that agents remaining aligned with human values also maintain alignment with each other.
AI & Machine LearningDeep TechSector Agnostic
Emmett Shear(CEO & Founder)inDavid Bloomin(Founder)inYatharth Agarwal(Cofounder)inAdam Goldstein(Board Member and Founder Emeritus)
Co-investorsJuniper Ventures Management, LlcLifelike CapitalMythos Ventures Management, LlcNight CapitalSancus VenturesSummit Peak Investments+2 more
Solum provides AI-driven software that automates administrative tasks for healthcare practices, including patient intake, insurance verification, prior authorizations, and scheduling.
AI & Machine LearningHealthtechSaaSSan Francisco, US
JP Montoya(Founder)inNoam Grebler
Co-investorsBAMCAPFundersClubHead & Heart CapitalMaiora Rebel VenturesRebel FundVentureSouq+8 more
Wavepaths develops adaptive therapeutic music designed to support mental health and wellness practitioners in their sessions.
Digital HealthMental HealthWellness & Fitness
Mendel Kaelen(Founder & CEO)in
Co-investorsMITONReflex CapitalTabula Rasa VenturesEmpath VenturesNeo Kuma VenturesPalo Santo VC
Wright Electric develops high-power-density power systems and inverter generators for defense, aerospace, commercial, and industrial applications.
Advanced ManufacturingClimate TechDefense TechEnergyHardwareSpace TechAlbany, US
Jeff Engler(CEO)inDoug Griswold(Founder)in
Co-investorsAAF Management Ltd.Evergreen Climate InnovationsJude GomilaY CombinatorAgrolimen VenturesEndure Capital+4 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
Bexson BiomedicalCausative Labs
Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.






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