First In Ventures — Full Portfolio

Pluton is developing a sun-powered, soil-surface biological nutrient system that uses photosynthetic microbial consortia to fix atmospheric nitrogen, improve phosphorus availability, and add carbon to soil for crop growers.

AgTechBiotechClimate TechSt. Louis, US

Barry Goldman(Co-founder)inElizabeth Gallegos(Chief Executive Officer)inJSJerry Steiner(Executive Chair)inCWCharlie Walch(Executive Officer, Director)inGlendon Schuster(Director)

Co-investorsILIllumina VenturesRARadicle GrowthFAFall Line CapitalGRGrantham FoundationRARA CapitalTHThe Yield Lab+3 more

Baltimore-based immunology company focused on treatments for cancer and autoimmune disorders; raised an $11.5 million Series C led by First In Ventures.

BiotechBaltimore, US

DSDavid S. Block(Executive Officer, Director)Elizabeth C. Block(Executive Officer)Raymond Shinazi(Director)Joseph Klein(Director)Mark Lerner(Director)

BoardCharles Polsky(Director)

Board seatKRKyle Rusconi· per SEC Form D

Co-investorsBRBrace Pharma

4baseCare delivers personalized cancer care using genomic data, AI analytics, and clinico-genomic datasets tailored to different populations.

AI & Machine LearningBiotechDigital HealthHealthtechMedical Devices

HGHitesh Goswami(Founder/CEO)inKRKshitij Rishi(COO)inPPPuneet Pantane(CDO)inDr. Giridharan Periyasamy

Co-investorsGRgrowX VenturesMEMerak VenturesMOMount Judi VenturesSESeason Two VenturesYAYali Capital

N-able delivers unified cybersecurity and data protection solutions including endpoint management (N-central), AI-powered threat detection and response (Adlumin), and disaster recovery services (Cove).

AI & Machine LearningCloud ComputingCybersecurityEnterprise SoftwareAlexandria, US

RSRobert S. Jonhston(Executive Officer, Director)

Co-investorsBABankTech VenturesJHJHH vcSYSyn Ventures Seed Management LlcWAWashington Harbour PartnersFIFirst InLELeawood Venture Capital Llc

Antithesis provides deterministic simulation testing software that automatically finds and reproduces bugs in mission-critical software systems.

AI & Machine LearningDeveloper ToolsEnterprise SoftwareSaaS

WWWill Wilson(Founder)inDSDave Scherer(Founder)NLNick Lavezzo(Founder)inDavid Scherer(Founder)

Co-investorsAMAmplify PartnersTATamarack GlobalBEBeaconsfield CapitalBOBoulder VenturesFRFrontline VenturesNANat Turner+5 more

EcoBiotaX develops a microbial ecology platform that uses AI (its ecoSat computational platform) and biological methods to discover and construct natural bacterial communities for specific biological functions.

AgTechAI & Machine LearningBiotech

Naama Geva-Zatorsky(Co-Founder)inSHShay Hilel(Co-Founder & CEO)inDLDean Light(Co-Founder & CTO)in

Co-investorsZOZORA

Broken String Biosciences develops tools for genome-wide on- and off-target analysis in gene editing, enabling in-house detection and characterization of gene editing-induced DNA breaks.

AI & Machine LearningBiotechDeep Tech

Co-investorsHEHeran PartnersILIllumina VenturesKOKorysMÉMérieux Equity Partners

CellDom develops CloneXplorer, a live single-cell assay platform combining functional imaging, molecular readouts, and integrated cell retrieval for high-resolution cell analysis.

BiotechDeep TechHardwareMedical Devices

Co-investorsTSTSVC

Felix Biotechnology develops a digital platform for designing viruses intended to combat antimicrobial resistance.

BiotechHealthtechSan Francisco, US

RMRobert McBride(Founder)inVMVivek Mutalik(Founder)inPTPaul Turner(Founder)inNatalie Ma(Founder)

Co-investorsPOPoint72 VenturesY Y CombinatorAGAgrolimen VenturesPIPioneerTATalosVC

Flightpath Biosciences develops microbiome-sparing, pathogen-specific drug candidates to treat infection-associated diseases by selectively targeting harmful bacteria while preserving healthy microbial communities.

BiotechDeep TechDigital HealthHealthtechMedical DevicesBirmingham, US

MTMatt Tindall(Founder)inMark P. de Souza(Executive Officer, Director)

BoardCurtis Scribner(Director)Cristina Larkin(Director)

Co-investorsIDID VenturesMIMichigan RiseWMWMU Biosciences Research & Commercialization CenterACActive Capital

Flowscope deploys AI agents that learn how businesses operate and automate work on top of existing systems within days.

AI & Machine LearningDeveloper ToolsEnterprise SoftwareSan Francisco, US

SMSamuel Mirpuri(Founder)inJLJavier Leguina(Founder)in

Co-investorsRERed Forest CapitalY Y CombinatorANAnderson Growth PartnersX2X26

Futura Genomics provides accredited genetic testing services that deliver personalized health and ancestry insights tailored to diverse populations, with particular focus on African heritage.

BiotechConsumerDigital HealthHealthtech

Lassogen engineers lasso peptides — structurally unique 3D scaffolds — into therapeutics it calls Lassotides, designed to combine the strengths of antibodies and small molecules.

AI & Machine LearningBiotechSan Diego, US

Mark J Burk(Executive Officer)in

Co-investorsBEBetter Ventures Central LlcPLPlayground Global

Alpenglow Biosciences develops the Aurora 3D spatial biology platform, combining open-top light-sheet microscopy, volumetric data processing, and AI analysis to turn intact tissue into quantitative 3D data.

AI & Machine LearningBiotechMedical Devices

Mable is a genomics-based telehealth platform that provides personalized migraine care by analyzing patients' genetic and biomarker data to inform individualized treatment plans.

AI & Machine LearningBiotechDigital HealthHealthtechMedical DevicesLondon, GB

RRRoman Rothaermel(Founder)inITInna Thalmann(Founder)inCEChris EijsboutsinKumeren GovnderArik Keller(Founder)Eric Carlstrom(Founder)

Co-investorsINInitialized CapitalUNUnderscore VCVEVenrockY Y CombinatorARArkitekt VenturesG2G20 Ventures+1 more

Medic Life Sciences applies CRISPR functional genomics in 3D patient tumor-like cancer models to identify biomarkers, synthetic lethality, and resistance mutations for oncology drug development.

BiotechDeep TechHealthtech

Kyuho Han(Chief Executive Officer/Co-Founder)Hong-Pyo Lee(Chief Technology Officer/Co-Founder)

Co-investorsBIBig Basin CapitalSASazze

Mitra develops a non-invasive skin diagnostics platform that combines clinical trials, skin sampling, next-generation sequencing, and data science to guide the design of age-rejuvenating skincare compounds.

BiotechDeep TechDigital HealthHealthtechLongevityMedical DevicesLondon, GB

SKShakiba Kaveh(CEO)inCBCristiana Banila(CTO)in

Co-investorsENEntrepreneur FirstMEMerian Ventures

MultiplAI Health is developing an RNA-sequencing and AI-based whole blood screening test to detect complex diseases, with a focus on cardiovascular disorders and cancer.

AI & Machine LearningBiotechDigital Health

HealthtechLondon

Roman Rothaermel(Executive Officer, Director, Promoter)Tom Kent(Executive Officer, Director, Promoter)Inna Thalmann(Executive Officer, Director, Promoter)Parul Singh(Director)

Parallel Health offers a skincare product line addressing aging through microbiome science, including peptide creams and cleansers designed to target the hallmarks of skin aging.

BiotechConsumerDigital HealthDirect to ConsumerHealthtechWellness & Fitness

NBNathan Brown(Founder)inNatalise Kalea Robinson(Founder)

Co-investorsAXAxial VCHYHyphen Capital

Stem Pharm develops therapeutics using stem cell technology for disease treatment and drug discovery.

BiotechDeep TechHealthtechMedical DevicesNew MaterialsMadison, US

CLConnie Lebakken(COO)inBMBill Murphy(CSO)inSteven Visuri(CEO)inRGRyan Gordon(Sr. V.P. of Business Development and Commercialization)in

Tailor Bio develops targeted cancer therapies for tumors characterized by chromosomal instability, working in the field of precision oncology.

BiotechHealthtech

Co-investorsJIJIC Venture Growth InvestmentsANANRINENew Enterprise Associates (NEA)SPSpiral CapitalY Y Combinator

Yali develops fermentation technology to produce sustainable fats and lipids for alternative dairy products like ice cream, butter, and milk, using fewer inputs than conventional sources.

BiotechCleantechClimate TechFoodTech

Co-investorsFTFTW VenturesS2S2G InvestmentsCRCRCM VenturesTHThird Kind Venture Capital