CLI Ventures — Full Portfolio

Guardant Health develops blood-based testing (liquid biopsy) for cancer detection and monitoring across all stages of the disease.

BiotechDigital HealthHealthtechMedical DevicesRedwood City, US

ATAmirAli Talasaz(Founder)inHEHelmy Eltoukhy(Founder)inMWMichael Wiley(Executive Officer)inMichael Bell(Chief Financial Officer)Darya Chudova(Chief Technology Officer)inCECraig Eagle(Chief Medical Officer)in

Co-investors8V8VCAUAUTHENTIC VENTURESCOCota CapitalFEFelicis VenturesKHKhosla VenturesKNKnockout Capital+11 more

Synlogic develops synthetic biology-based biotherapeutics that use engineered living organisms to treat diseases.

BiotechDeep TechMedical DevicesCambridge, US

BCBharatt Chowrira(Executive Officer)inMSMichael Sheahan(Executive Officer)Jose Carlos Gutierrez-Ramos(Executive Officer, Director)inPMPaul Miller(Executive Officer)inABAoife Brennan(Executive Officer)inTSTodd Shegog(Executive Officer)in

Co-investorsATAtlas VentureNENew Enterprise Associates (NEA)NSNSG VenturesPFPfizer Venture InvestmentsSOSofinnova VenturesSOSolasta Ventures+1 more

Arthena operates a financial fund that enables high-net-worth individuals to invest in art by using statistical models trained on auction data to identify and purchase artworks expected to appreciate with low correlation to traditional asset classes.

FintechNew York City, US

MDMadelaine D'Angelo(CEO)inMDMichael DAngelo(CTO)inAdrian WisernigWill Holley(Software Engineer)Joseph Sayad(Software Engineer)Paulina Amato(Operations)

Co-investorsANAnya CapitalCLClick VenturesFIFirstrock CapitalY Y Combinator191984 Ventures Management, Llc202020 Ventures+10 more

Civil Maps develops artificial intelligence for autonomous vehicle perception, creating continental-scale HD 3D maps and centimeter-level localization systems.

AI & Machine LearningDeep TechMobility & TransportationSilicon Valley, US

Co-investorsELElev8.vcREReshapeSCScrum VenturesTSTSVCWEWestern Technology InvestmentAMAME Cloud Ventures+2 more

CRISPR Therapeutics is a biotechnology company developing gene-based medicines using CRISPR/Cas9 gene-editing technology.

BiotechDeep TechHealthtechZug, CH

Emmanuelle Charpentier(Founder)SKSamarth Kulkarni(Chief Executive Officer and Chairman of the Board)inJRJames R. Kasinger(General Counsel and Secretary)inSKStephen Kennedy(Head of Technical Operations)inMWMegan Wherry Menner(Head of Human Resources)inNPNaimish Patel(Chief Medical Officer)in

Co-investorsAVAvoro Capital AdvisorsKHKhosla VenturesNENew Enterprise Associates (NEA)SRSR One Capital ManagementVEVersant VenturesWEWellington Management+2 more

CStorePro provides cloud-based back-office software for convenience store operators.

Cloud ComputingData & Infrastructure

Arif Momin(Founder)in

Co-investors50500 GlobalFOForefront VentureLALaunchCapitalSASandalphon CapitalSISilicon Badia

Xoilac TV is a Vietnamese website for streaming live football matches with free Vietnamese-language commentary, covering leagues such as the Premier League, La Liga, Serie A, Bundesliga, V-League and World Cup.

ConsumerMedia & EntertainmentSports TechĐà Nẵng, VN

Ahmed Haider(Founder)Matthew Sweeny(Founder)inTom Bass(Founder)Võ Hà Chiến(Founder)

Co-investorsZIZillionizeLOLowercase CapitalMEMenlo VenturesQUQualcomm VenturesWOWorld Innovation Lab (WiL)

Flirtey operates a drone delivery network that transports goods directly to customers for last-mile logistics.

Advanced ManufacturingRoboticsBlountville, US

MSMatthew Sweeny(CEO)inTom Bass(COO \u0026 Head of Product)

Co-investorsY Y CombinatorACACE & CompanyAMAmasiaBEBessemer Venture PartnersDHDHVCELElysium Venture Capital+13 more

Genalyte develops Merlin, a real-time diagnostic system that performs laboratory testing directly in clinical settings and integrates results with electronic health records.

Digital HealthHardwareHealthtechMedical DevicesSan Diego, US

CGCary Gunn(Founder)in

Co-investorsBIBioBritBOBoutique Venture PartnersCLClaremont Creek VenturesFUFusionX VenturesHBHBM Healthcare InvestmentsHBHBM Partners+7 more

Hiretual offers an AI agent-driven recruiting platform that handles the full hiring pipeline — candidate sourcing across 45+ platforms, branded career pages, ATS/CRM enrichment, applicant review, conversational screening, interview scheduling, and hiring analytics — directed from a single interface.

AI & Machine LearningHR TechSaaS

Immune Onc is a biotechnology company developing medicines to treat patients with hard-to-treat cancers and autoimmune diseases, with expertise in translational medicine and clinical development.

BiotechMedical DevicesPalo Alto, US

XCXiaoling Charlene Liao(Executive Officer, Director)Charlene Liao(Founder)in

BoardGuo-Liang Yu(Director)Liqun Luo(Director)

Co-investorsNONorthern Light Venture CapitalSHShangBay Capital LLCSTStartXVIVivo CapitalTRTriWise Capital

iMicrobes uses synthetic biology to develop cost-effective sustainable materials and replace conventional manufacturing processes.

BiotechCircular EconomyCleantechClimate TechHealthtechNew MaterialsSan Francisco, US

DGDerek Greenfield(CEO)inLCLiz Clarke(CTO)inNHNoah Helman(CSO)inAnne-Marie Rosche(Office Manager)

Co-investorsFIFirst Bight VenturesJUJude GomilaJUJuniperPOPoint Reyes ManagementSTStartXY Y Combinator+8 more

InsideMaps provides 3D property documentation and virtual tour technology for real estate professionals, vacation rentals, hotels, and event spaces.

PropTechSaaS

Co-investorsCOColopl NextGFGFR FundRERET VenturesULUlu Ventures

Leaf Healthcare makes the LEAF Patient Monitoring System, a wearable sensor and software interface that helps hospital nurses create and follow patient turning protocols to prevent hospital-acquired pressure injuries.

Digital HealthHealthtechMedical DevicesPleasanton, US

MVMark V. Weckwerth(Executive Officer, Director)in

BoardDonald R. Scifres(Director)Ronald L. Chez(Director)James Holtz(Director)

Neocis develops Yomi, a robotic surgical platform that assists clinicians during dental implant surgery with planning, surgical, and restorative software features.

HealthtechMedical DevicesRoboticsMiami, US

AMAlon Mozes(Founder)inJSJuan Salcedo(Founder)inDMDennis Moses(Chief Technical Officer)inACAndres Carrillo(VP of Product)inJFJorge Fernandes(VP of Quality & Regulatory)inGGGabe Goldberg(VP of Marketing)in

Co-investorsINIntuitive VenturesNONorwest Venture PartnersVIVivo CapitalFLFlorida Opportunity FundMIMithril Capital ManagementNVNVIDIA+5 more

Sentieon develops optimized bioinformatics algorithms for genomic data processing, particularly for precision medicine applications.

AI & Machine LearningBiotechData & InfrastructureDeep TechHealthtechSan Jose, US

Jun Yein

Co-investorsGRGRC SinogreenMIMission BiocapitalTETen Coves Capital

BiotechPalo Alto, US

Andrew Radin(President, Treasurer, Secretary and Sole Director)

Waypoint offers a platform for commercial real estate teams that centralizes financial, leasing, operational, and strategic data into a single hub, with workflow automation, reporting templates, task management, and collaboration tools.

Enterprise SoftwarePropTechSaaS