Department of Health and Human Services
Grant agency1 people tracked
Investment thesis
Health-focused SBIR/STTR awards outside NIH's program — ARPA-H, ACL, and other HHS components funding care delivery, assistive technology, and health data systems.
SBIR/STTR awards · non-dilutive funding
Federal grants and contracts to small businesses — no equity taken. Awards on record 1983–2023.
9,317 Phase I · 2,836 Phase II · 203 via STTR · most-funded states: CA, MA, MD, NY, TX
| Recent awardees | Phase | Year | Amount |
|---|---|---|---|
| CATHBUDDY INCSyracuse, NY | Phase II | 2023 | $575K |
| ADARACTReno, NV | Phase I | 2023 | $99.3K |
| OBJECTIVE ED, INC.Wellington, FL | Phase II | 2023 | $575K |
| Impulse Wellness LLCRaleigh, NC | Phase II | 2023 | $575K |
| LIBERATING TECHNOLOGIES INCHolliston, MA | Phase II | 2023 | $574.5K |
| ALTEC, INCNatick, MA | Phase II | 2023 | $570.4K |
| OBJECTIVE ED, INC.Wellington, FL | Phase I | 2023 | $100K |
| CREATEABILITY CONCEPTS INCIndianapolis, IN | Phase I | 2023 | $100K |
| VALAR SYSTEMS LLCBend, OR | Phase I | 2023 | $100K |
| CREATEABILITY CONCEPTS INCIndianapolis, IN | Phase I | 2023 | $100K |
| SPRINGWEAR, LLCBaltimore, MD | Phase I | 2023 | $100K |
| LEARNING Q LLCZephyr Cove, NV | Phase I | 2023 | $100K |
| LEARNING Q LLCZephyr Cove, NV | Phase I | 2023 | $100K |
| ADVANCED LIFE TECHNOLOGIES, LLCSanta Barbara, CA | Phase I | 2023 | $100K |
| SERIOUS HEALTH LLCChattanooga, TN | Phase I | 2023 | $99.7K |
| GOOMWAVE LLCErie, CO | Phase I | 2023 | $99.4K |
| ORTHOCARE INNOVATIONS LLCEdmonds, WA | Phase I | 2023 | $99K |
| Kalogon, IncMelbourne, FL | Phase I | 2022 | $99.9K |
| KAMIN CONSULTING INCDallas, TX | Phase II | 2022 | $575K |
| CHARMTECH LABS LLCBuffalo, NY | Phase II | 2022 | $575K |
| ASSISTECH SYSTEMS LLCEugene, OR | Phase II | 2022 | $575K |
| BEHAVIORAL TECHNOLOGIES CONSULTING ORGANIZATION, INCBasehor, TX | Phase II | 2022 | $575K |
| NEUROTECHR3 INC.Warren, NJ | Phase I | 2022 | $100K |
| ASSISTECH SYSTEMS LLCEugene, OR | Phase I | 2022 | $100K |
| SPRINGWEAR, LLCBaltimore, MD | Phase I | 2022 | $100K |
| ALCHEMIE SOLUTIONS, INC.Bloomfield Hills, MA | Phase I | 2022 | $100K |
| Impulse Wellness LLCRaleigh, NC | Phase I | 2022 | $100K |
| LIVE AND LEARN SOCIETYMorro Bay, CA | Phase I | 2022 | $100K |
| LIBERATING TECHNOLOGIES INCHolliston, MA | Phase I | 2022 | $100K |
| OBJECTIVE ED, INC.Wellington, FL | Phase I | 2022 | $99.7K |
Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are non-dilutive — the agency takes no equity.
Team · 1 people
from curatedFounder mafia
The Department of Health and Human Services mafia →11 people who came through Department of Health and Human Services went on to found or lead other companies.
What they invest in
from 125 of 204 portfolio companiesDeep Tech ×52Hardware ×48Healthtech ×37Biotech ×25Medical Devices ×25New Materials ×20Digital Health ×15Defense Tech ×14
HQs:United States×43
Investments · 204 tracked
founders shown can be your intro pathBy year:2025 · 12022 · 12020 · 22017 · 62015 · 111997 · 122 dated
CEL-SCI Corporation is a biotech company developing immunotherapies, particularly Multikine, which is advancing through FDA regulatory processes.
BiotechHealthtechMedical DevicesVienna, US
Patricia B. Prichep(Executive Officer)Eyal Talor(Executive Officer)Geert R. Kersten(Chief Executive Officer)Daniel H. Zimmerman(Executive Officer)inJohn Cipriano(Executive Officer)
BoardPeter Young(Director)
Adaract develops high-performance artificial muscle actuators that provide stronger, lighter, and more compact motion solutions for applications in prosthetics, robotics, aerospace, and exoskeletons.
Advanced ManufacturingDeep TechHardwareMobility & TransportationRoboticsReno, US
Marcus D'Ambrosio(Co-founder)
Co-investorsStartupNV
ALT LLC engineers materials, structures, and on-device AI for robots, prosthetics, drones, and autonomous systems, combining synthetic tissues, high-strength composites, additive manufacturing, and edge machine learning.
AI & Machine LearningNew MaterialsRoboticsSanta Barbara, US
ASC develops global shutter flash LIDAR (gsf-LIDAR), a solid-state, non-scanning time-of-flight 3D imaging and ranging camera that produces distortion-free point clouds for optical navigation, mapping, and situational awareness.
AI & Machine LearningDeep TechHardware
Advanced Targeting Systems develops research reagents including saporin-based targeted toxins, pHast Conjugates for internalization assays, ZAP kits, and secondary antibodies.
BiotechHealthtech
Co-investorsID VenturesInvest Michigan
Ashwin-Ushas develops advanced materials and devices including IR-electrochromic variable-emittance skins for spacecraft thermal control and dynamic camouflage, wide-temperature ionic-liquid Li-ion batteries, electrochemical sensors for chemical agents and hazardous compounds, microwave-based medical waste remediation, and electrochromic eyewear.
Deep TechNew MaterialsSpace Tech
Cognitopia offers web-based self-management and executive functioning software used to set goals, track assignments and progress, and maintain communication for individuals in special education, independent living, and employment settings.
Digital HealthEdTechSaaS
Tom Keating(CEO & Founder)
Behavioral Technologies Consulting Organization (BTCO) provides organizational and behavior management consultation, supervision, and training in applied behavior analysis (ABA) for ABA therapy providers, school districts, and supervisees pursuing Board Certified Behavior Analyst credentials.
Digital HealthHealthtechMental HealthBasehor, US
Dr. Linda Heitzman-Powell(Founder)Kimberly Becker(COO (Chief Operating Officer))Christopher Powell(Financial Officer)
Brimrose designs and manufactures Acousto-Optic Tunable Filter (AOTF) components, NIR spectrometers, and hyperspectral imagers, offering custom optical solutions.
Deep TechHardwareSpace Tech
CathBuddy develops a reusable intermittent catheter system for people with spinal cord injuries and other catheter users, aiming to reduce single-use catheter waste and support patient independence.
HardwareHealthtechMedical DevicesWoodbury, US
Souvik Paul(CEO)Daniel Wollin(Director)John Neamonitis(Director)
Co-investorsHealth Wildcatters
CFD Research is a private company recognized on the Inc. 5000 list of America's fastest-growing private companies.
Deep Tech
Capti ReadBasix is a diagnostic reading assessment for secondary students (grades 3-12) that identifies the root causes of reading difficulties through six individual subtests, benchmark reporting, Lexile measures, and dyslexia risk screening.
EdTechSaaS
New Castle, US
Erica Nemser(Executive Officer, Director)inBill Charlton(Executive Officer)Bennett Nemser(Director)
BoardGuido Radaelli(Director)Chris Erickson(Director)Tony Sun(Director)
Co-investorsChevron Technology VenturesPangaea Ventures
Continuum Dynamics Inc is a research and development firm serving government and industry, providing analysis, software R&D, and testing across fields such as rotorcraft, flight simulation, nuclear engineering, and numerical methods.
Deep TechDefense TechEnergy
San Diego, US
Anders Dale(Director)Chris Airriess(Executive Officer, Director)Guri Stark(Executive Officer, Director)Nathan White(Executive Officer, Director)Thomas Barich(Executive Officer)Paul Mirabella(Director)
Creare is an engineering research and development firm that solves complex technical problems and develops new technologies for industry and government customers.
Deep TechHardwareSpace Tech
Dr. Jay Rozzi(Senior Staff)Jeff Breedlove(Senior Staff)Dr. Odile Clavier(Senior Staff)Dr. Patrick Magari(Senior Staff)
Creatv is a company with three divisions: a microfabrication and electroplating services unit, a cancer diagnostics research division (Creatv Bio) that uses CellSieve microfilters to isolate and image cancer-associated cells from blood, and LifeTracDx, which offers diagnostic blood testing through a CLIA-certified laboratory.
BiotechHardwareMedical Devices
Detroit R&D develops and sells life-science research products including ELISA kits, antibodies, and antibody/protein/glycan microarrays for drug metabolism, cancer biomarkers, oxidative stress, mitochondrial function, and air pollution exposure.
BiotechHardwareHealthtech
Annie De Groot MD(Founder)inRich-Henry Schabowsky, PhD, JDin
Co-investorsSV Health Investors
Fischer Imaging develops diagnostic imaging products, continuing a long-standing legacy in the medical imaging field.
HardwareHealthtechMedical Devices
Flint Rehab makes FDA-listed neurorehabilitation devices and apps — including the FitMi full-body rehab tool, MusicGlove hand therapy, the Flex AFO foot-drop brace, and a speech and cognitive therapy app — for people recovering at home from stroke, brain injury, cerebral palsy, and other neurological conditions.
Digital HealthHardwareMedical Devices
FTI Defense builds a mission data platform combining data analytics, modeling and simulation, and generative AI tools — including the WOPR wargaming platform and an AI Sidekick application — to support military and defense operations.
AI & Machine LearningCybersecurityDefense Tech
FTL Labs develops transitional technology, taking applied science research from academia and bringing it toward commercial applications.
Deep Tech
IBC develops and manufactures high-purity macrocycles and chelating agents (the MacroLig product line) and Molecular Recognition Technology (MRT) systems for highly selective metal separations.
Circular EconomyCleantechNew Materials
iRT is a behavioral sciences research company that conducts translational scientific studies, evaluation and technical-assistance projects, and develops research-based products such as media-literacy education programs aimed at substance misuse prevention.
Digital HealthEdTechHealthtechDurham, US
Innovative Design Labs (IDL) is a research and development company that develops technology from concept to manufacturing, including medical training simulators, manikins, and non-contact health monitoring systems.
EdTechHardwareMedical DevicesMinneapolis, US
Inovati develops Kinetic Metallization, a low-pressure cold spray additive manufacturing process that deposits metals, ceramics, and polymers onto surfaces without melting the feedstock or substrate.
Advanced ManufacturingHardwareNew Materials
ILS (Integrated Laboratory Systems), now an Inotiv company, provides integrated, multidisciplinary toxicology services supporting research and regulatory compliance needs for clients.
BiotechHealthtech
Trifoia provides online training and educational media services, including scenario-based explainer videos, digital course development, accessibility compliance, LMS hosting, and evaluative research.
EdTechFuture of WorkMedia & Entertainment
Advanced ManufacturingCosta Mesa, US
John C. Carson(Executive Officer, Director)John J Stuart, Jr.(Director)James W Justice(Executive Officer, Director)
Kalogon develops advanced seating technologies, including smart cushions, aimed at improving comfort and health for people who must sit for extended periods.
HardwareHealthtechMedical DevicesMelbourne, US
Aaron Jones(Co-Founder & Account Manager)Timothy Balz(Founder)Carla Borsoi(VP of Marketing & Research)Jon Buford(Engineering Manager)Amanda Krantz(VP of Strategy & Business Development)Paul Benz(VP of Sales)
Co-investorsEnable VenturesDeepWork Capital
KamTek provides biorepository operations and laboratory services, including cryopreservation, cold-chain storage, sample processing, molecular biology, microbiology, and cellular services for biospecimens.
BiotechHealthtechLogistics & Supply Chain
Live & Learn, Inc. is a consultancy that partners with nonprofits, governments, and universities on participatory action research, offering grant writing, program design, R&D, and evaluation services in public health and social policy.
Future of WorkHealthtechImpact & Social GoodSan Luis Obispo, US
Lynntech is a research and development company whose scientists and engineers create technologies across areas including artificial intelligence, medical diagnostic devices, hybrid energy systems, biomedical therapies, defense safety and training, and additive manufacturing.
Deep TechDefense TechMedical Devices
Meadowlark Optics designs and manufactures polarization systems and components, including liquid crystal devices spanning UV to MWIR, with products such as shutters, rotators, waveplates/retarders, spatial light modulators, tunable optical filters, polarizers and polarimeters.
Advanced ManufacturingDeep TechHardware
Tom Baur
MDLogix offers bhworks, a platform for schools and states that unifies six modules — behavioral and mental health, nursing, universal screening, attendance/truancy, Medicaid billing, and special education/IEP — under a single Multi-Tiered System of Supports framework.
Digital HealthEdTechMental Health
Metron builds data analytics, decision-support, autonomy, and sensor-processing software using probabilistic modeling, signal processing, AI, and data fusion.
AI & Machine LearningDeep TechDefense Tech
HealthtechDexter, US
Scott Merz(Executive Officer, Director)Catherine Schmidt(Executive Officer)Robert Bartlett(Director)Robert Foster(Executive Officer, Director)
BoardRio Foster(Director)Christopher Ball(Director)
MTR (Membrane Technology and Research) designs modular membrane systems for industrial gas separation, including monomer and hydrogen recovery, LPG recovery, syngas upgrading, and CO2 removal from natural gas.
Advanced ManufacturingCleantechNew MaterialsNewark, US
Richard Baker(Founder)
Co-investorsClimate Investment
NeuraLynx builds neural recording data acquisition and analysis systems, including its Digital Lynx multichannel recording and stimulation platform, telemetry systems, and portable acquisition tools.
Deep TechHardwareHealthtech
NeuroTechR3 makes R3THA, an AI-driven neurorehabilitation system that uses adaptive exergames and real-time biofeedback to improve gross and fine motor hand and arm function.
AI & Machine LearningDigital HealthMedical Devices
Nexceris develops custom catalysts and electrochemical materials for clean energy and advanced manufacturing applications, including sustainable aviation fuel pathways (Fischer-Tropsch, Methanol-to-Jet, Alcohol-to-Jet, and Power-to-Liquids).
CleantechEnergyNew Materials
Optra Edge is an integrated hardware and software platform for deploying edge AI applications, letting businesses run AI outside the cloud with remote provisioning, fleet monitoring, and chainable software "skills." It offers industry-tailored offerings for manufacturing, retail, transportation, and healthcare.
AI & Machine LearningHardwareIoT
Organix is a US-based contract research organization (CRO) specializing in organic and medicinal chemistry, offering custom synthesis, analytical services, and contract R&D with expertise in lipids, oligonucleotides, and polymer chemistry.
BiotechDeep TechNew Materials
pathVu provides sidewalk mapping and assessment services that collect and analyze pathway condition data, producing GIS outputs to characterize walkability and accessibility.
Data & InfrastructureGovTechMobility & TransportationPittsburgh, US
Co-investorsInvestcorp
Pison manufactures a wearable neural watch that measures cognitive and physiological performance by reading signals between the brain and muscles.
HardwareHealthtechWellness & FitnessBoston, US
Dexter Ang(Executive Officer, Director)Salil Patel(Director)John Croteau(Executive Officer, Director)
BoardJames Hunt(Director)David Cipoletta(Director)
Co-investorsBose VenturesDecisive PointIn-Q-TelIronGate Capital AdvisorsDorm RoomLavrock Ventures
Polestar Technologies develops customized optical sensing technologies and sterilizable sensors that measure parameters such as pH, oxygen (O2), and carbon dioxide (CO2).
Deep TechHardwareIoT
Pressure Profile Systems (PPS) designs capacitive tactile pressure sensors and its Chameleon software, which converts raw pressure data into visualizations for mapping and measuring contact mechanics.
Deep TechHardwareIoT
Proportional Technologies (PTI) develops boron-coated straw detector technology as a replacement for Helium-3 in neutron detection.
Deep TechHardware
RJ Lee Group is a scientific consulting firm and industrial forensics laboratory that provides materials and environmental testing, including petrographic analysis, chemical testing, and expert witness services.
CleantechDeep TechNew Materials
Scientific Systems develops AI-powered autonomy technology for defense applications, serving U.S. government, aerospace, and defense organizations.
AI & Machine LearningDefense TechRoboticsBurlington, US
Sendero Group developed accessible GPS software and navigation products for blind and visually impaired users, powering devices like BrailleNote and Braille Sense and turn-by-turn apps including Seeing Eye GPS and RNIB Navigator.
ConsumerHealthtechMobility & Transportation
Sensimetrics Corporation performs research, development, and consulting in human communication, focusing on speech, hearing, acoustics, and digital signal processing.
Deep TechHardwareHealthtech
Sequella is a clinical-stage pharmaceutical company developing antibiotics to treat drug-resistant bacterial, fungal, and parasitic infections, including tuberculosis, MDR-TB, XDR-TB, H. pylori, and C. difficile.
BiotechHealthtechRockville, US
Carol A. Nacy(Executive Officer, Director)Lawrence Miller(Executive Officer)Leo Einck(Executive Officer, Director)
BoardBradley Rotter(Director)Paige MacDonald(Director)John Friedman(Director)
SINTX manufactures silicon nitride and other advanced ceramics, engineering medical- and industrial-grade materials for uses such as spinal implants, hip and knee joint prosthetics, and additive manufacturing.
BiotechMedical DevicesNew Materials
SpaceFactory (formerly AI SpaceFactory) builds robotic autonomous systems and 3D-printing technology that convert lunar regolith and other native feedstocks into stabilized, load-bearing surfaces and infrastructure for space and defense environments.
Construction TechRoboticsSpace Tech
SpringWear Technology develops a wearable, spring-powered hand exoskeleton for at-home stroke rehabilitation, aimed at restoring hand function.
Digital HealthHardwareMedical Devices
Stottler Henke builds artificial intelligence software systems and provides consulting for applications including education and training, planning and scheduling, decision support, knowledge management, and autonomous systems.
AI & Machine LearningEnterprise SoftwareGovTech
STI Aerospace provides flight controls, modeling, simulation, pilot assessment, and training solutions for government and industry partners in the aerospace sector, with a focus on incorporating human factors into system design and engineering.
Deep TechDefense TechHardware
TDA Research Inc. is a research and development company that develops commercial products and technologies across the defense/aerospace, medical, materials, and energy industries, bringing them to market through direct sales, distribution agreements, spin-off companies, and licensing.
Deep TechEnergyNew MaterialsGolden, US
TA&T develops and manufactures advanced ceramic materials, including transparent Spinel ceramic armor, electro-optical windows, ceramic composites, and coatings, for aerospace, defense, industrial, automotive, and medical applications.
Advanced ManufacturingDeep TechNew Materials
Thornton Tomasetti applies engineering and scientific principles to the design, construction and performance of buildings, offering services such as structural engineering, forensics, flood risk protection, building enclosure renewal, rigging engineering for live events, and sustainability/life-cycle material analysis.
Climate TechConstruction TechDeep TechNew York, US
Touch Graphics Inc designs products and exhibits that convey spatial information through the sense of touch, aimed at accessibility for people who are blind or visually impaired.
HardwareHealthtech
Tristan Technologies designs and fabricates custom and standard SQUID (superconducting quantum interference device) magnetometer systems for detecting weak magnetic signals, used in scientific laboratory research and medical biomagnetic imaging.
Deep TechHardwareMedical DevicesSan Diego, US
Ultramet develops and manufactures refractory metals, platinum group metals, and ceramics—including coatings, freestanding structures, open-cell foams, and ceramic matrix composites—for use in extreme, high-performance environments.
Advanced ManufacturingDeep TechNew Materials
USDTL provides forensic toxicology testing and drug and alcohol testing services.
BiotechDigital HealthEnterprise SoftwareHealthtech
Douglas Lewis(Founder, President, and Scientific Director)
Co-investorsNorthlane Capital Partners
Vcom3D develops mixed reality medical simulation and training systems that integrate physical manikins and part-task trainers with virtual patients, anatomical overlays, and virtual medical equipment.
EdTechHealthtechMedical Devices
Browse all 204 investments with full details →
▶4 more tracked companies
VORTANT TECHNOLOGIES LLCWESTEST ENGINEERING CORPXIA LLCZyrobotics
Exits · 1
IPOs and acquisitions across the tracked portfolioCEL SCINYSE: CVM
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Kalogon · intelligence360.news · Jul 21, 2026










