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Department of Health and Human Services

Grant agency

1 people tracked

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Investment thesis

Health-focused SBIR/STTR awards outside NIH's program — ARPA-H, ACL, and other HHS components funding care delivery, assistive technology, and health data systems.

SBIR/STTR awards · non-dilutive funding

Federal grants and contracts to small businesses — no equity taken. Awards on record 1983–2023.

Awards
12,153
Companies funded
3,817
Total awarded
$2.2B
Median award
$95K

9,317 Phase I · 2,836 Phase II · 203 via STTR · most-funded states: CA, MA, MD, NY, TX

Recent awardeesPhaseYearAmount
CATHBUDDY INCSyracuse, NYPhase II2023$575K
ADARACTReno, NVPhase I2023$99.3K
OBJECTIVE ED, INC.Wellington, FLPhase II2023$575K
Impulse Wellness LLCRaleigh, NCPhase II2023$575K
LIBERATING TECHNOLOGIES INCHolliston, MAPhase II2023$574.5K
ALTEC, INCNatick, MAPhase II2023$570.4K
OBJECTIVE ED, INC.Wellington, FLPhase I2023$100K
CREATEABILITY CONCEPTS INCIndianapolis, INPhase I2023$100K
VALAR SYSTEMS LLCBend, ORPhase I2023$100K
CREATEABILITY CONCEPTS INCIndianapolis, INPhase I2023$100K
SPRINGWEAR, LLCBaltimore, MDPhase I2023$100K
LEARNING Q LLCZephyr Cove, NVPhase I2023$100K
LEARNING Q LLCZephyr Cove, NVPhase I2023$100K
ADVANCED LIFE TECHNOLOGIES, LLCSanta Barbara, CAPhase I2023$100K
SERIOUS HEALTH LLCChattanooga, TNPhase I2023$99.7K
GOOMWAVE LLCErie, COPhase I2023$99.4K
ORTHOCARE INNOVATIONS LLCEdmonds, WAPhase I2023$99K
Kalogon, IncMelbourne, FLPhase I2022$99.9K
KAMIN CONSULTING INCDallas, TXPhase II2022$575K
CHARMTECH LABS LLCBuffalo, NYPhase II2022$575K
ASSISTECH SYSTEMS LLCEugene, ORPhase II2022$575K
BEHAVIORAL TECHNOLOGIES CONSULTING ORGANIZATION, INCBasehor, TXPhase II2022$575K
NEUROTECHR3 INC.Warren, NJPhase I2022$100K
ASSISTECH SYSTEMS LLCEugene, ORPhase I2022$100K
SPRINGWEAR, LLCBaltimore, MDPhase I2022$100K
ALCHEMIE SOLUTIONS, INC.Bloomfield Hills, MAPhase I2022$100K
Impulse Wellness LLCRaleigh, NCPhase I2022$100K
LIVE AND LEARN SOCIETYMorro Bay, CAPhase I2022$100K
LIBERATING TECHNOLOGIES INCHolliston, MAPhase I2022$100K
OBJECTIVE ED, INC.Wellington, FLPhase I2022$99.7K

Source: SBIR.gov award data (U.S. Small Business Administration). SBIR/STTR awards are non-dilutive — the agency takes no equity.

Instruments
Grants
Last 12 months
1 investment
Tracked investments
204

Team · 1 people

from curated

11 people who came through Department of Health and Human Services went on to found or lead other companies.

What they invest in

from 125 of 204 portfolio companies

Deep Tech ×52Hardware ×48Healthtech ×37Biotech ×25Medical Devices ×25New Materials ×20Digital Health ×15Defense Tech ×14

HQs:United States×43

Investments · 204 tracked

founders shown can be your intro path

By year:2025 · 12022 · 12020 · 22017 · 62015 · 111997 · 122 dated

CEL SCIcel-sci.comin𝕏NYSE: CVM

CEL-SCI Corporation is a biotech company developing immunotherapies, particularly Multikine, which is advancing through FDA regulatory processes.

BiotechHealthtechMedical DevicesVienna, US

Patricia B. Prichep(Executive Officer)Eyal Talor(Executive Officer)Geert R. Kersten(Chief Executive Officer)Daniel H. Zimmerman(Executive Officer)inJohn Cipriano(Executive Officer)

BoardPeter Young(Director)

3-C INSTITUTE FOR SOCIAL DEVELOPMENT INC3cisd.comSep 2015 · $575K

3C Institute builds custom technology and digital health software for researchers, educators, program developers, and clinicians, supporting the development and delivery of research-based programs.

Digital HealthEdTechHealthtech

ACME EXPRESS, INCacmex.com
Active Signal Technologies, Inc.activesignaltech.com
ADA TECHNOLOGIES, INC.adatech.com

ADA Technologies is a Colorado-based manufacturing company with an R&D division that develops, manufactures, and delivers customized products for advanced market customers.

Advanced ManufacturingDeep TechHardware

ADARACTadaract.com

Adaract develops high-performance artificial muscle actuators that provide stronger, lighter, and more compact motion solutions for applications in prosthetics, robotics, aerospace, and exoskeletons.

Advanced ManufacturingDeep TechHardwareMobility & TransportationRoboticsReno, US

Marcus D'Ambrosio(Co-founder)

Co-investorsStartupNV

ADELPHI TECHNOLOGY INCadelphitech.com

Adelphi Technology manufactures neutron generator products, including deuterium-tritium, deuterium-deuterium, and thermal (moderated) neutron sources with yields ranging from 10^7 to over 10^10 neutrons per second.

Advanced ManufacturingDeep TechHardware

ADVANCED BRAIN MONITORING, INC.b-alert.com
ADVANCED FUEL RESEARCH, INC.afrinc.com
ADVANCED LIFE TECHNOLOGIES, LLC3dalt.com𝕏

ALT LLC engineers materials, structures, and on-device AI for robots, prosthetics, drones, and autonomous systems, combining synthetic tissues, high-strength composites, additive manufacturing, and edge machine learning.

AI & Machine LearningNew MaterialsRoboticsSanta Barbara, US

ADVANCED SCIENTIFIC CONCEPTS, LLCasc3d.comin

ASC develops global shutter flash LIDAR (gsf-LIDAR), a solid-state, non-scanning time-of-flight 3D imaging and ranging camera that produces distortion-free point clouds for optical navigation, mapping, and situational awareness.

AI & Machine LearningDeep TechHardware

Advanced Targeting Systemsatsbio.comin

Advanced Targeting Systems develops research reagents including saporin-based targeted toxins, pHast Conjugates for internalization assays, ZAP kits, and secondary antibodies.

BiotechHealthtech

AEON IMAGING LLCaeonimaging.comSep 2017 · $99.5K

Aeon Imaging develops medical and scientific imaging technology, using confocal imaging based on the electronic aperture of CMOS sensors.

HardwareHealthtechMedical DevicesBloomington, US

Ann Elsner(Founder)

AERODYNE RESEARCH INCaerodyne.com

Aerodyne Research develops research-grade scientific instrumentation and provides measurement and R&D services focused on environmental and energy challenges.

Climate TechDeep TechHardware

AEROSOL DYNAMICS INCaerosol.us
ALAMEDA APPLIED SCIENCES CORPORATIONaasc.space

AASC develops electric propulsion systems for satellites that generate thrust by ionizing solid metallic puck fuel (its Metal Pulsed Thruster), avoiding fluids, tanks and heaters.

Deep TechHardwareSpace Tech

Alchemiealchem.ie

Co-investorsID VenturesInvest Michigan

ALTEC, INCaltecresearch.com

Altec develops human sensing and measurement technologies for applications in health science, operational security, and human performance.

Deep TechHardwareHealthtech

Carlo De Luca

Ambergenambergen.cominApr 2022 · $2M

BiotechWatertown, US

Kenneth Rothschild(Executive Officer, Director)Michael Easterling(Director)John Gillespie(Executive Officer, Director)Peter Finn(Executive Officer)Brian Rothschild(Director)

ANALATOM INCORPORATEDanalatom.com

Analatom builds hardware and software for automated inspection and condition monitoring of high-value assets such as aircraft, bridges, vehicles, pipelines, ships, and wind turbines.

AI & Machine LearningHardwareIoT

Analytical Instrument Systems Incaishome.com

Analytical Instrument Systems (AIS, Inc.) designs and supplies voltammetric electrochemical instruments for analyzing environmental conditions in extreme settings, from deep oceans to polar regions.

CleantechClimate TechHardware

ANASPHERE, INCanasphere.com

Anasphere, Inc. manufactures aerospace systems, including atmospheric sensors and inflation gas generators used in aviation testing, atmospheric research, and gas inflation applications.

Advanced ManufacturingHardwareLogan, US

Applied Biomathematics Incramas.com

RAMAS by Applied Biomathematics develops ecological risk software and offers consulting in risk analysis, predictive analytics, and specialized analytical methods for environmental and ecological problems.

AI & Machine LearningCleantechClimate Tech

Aradigm Corporationaradigm.com
Ashwin-Ushas Corporationashwin-ushas.com

Ashwin-Ushas develops advanced materials and devices including IR-electrochromic variable-emittance skins for spacecraft thermal control and dynamic camouflage, wide-temperature ionic-liquid Li-ion batteries, electrochemical sensors for chemical agents and hazardous compounds, microwave-based medical waste remediation, and electrochromic eyewear.

Deep TechNew MaterialsSpace Tech

ASSISTECH SYSTEMS LLCcognitopia.comin𝕏

Cognitopia offers web-based self-management and executive functioning software used to set goals, track assignments and progress, and maintain communication for individuals in special education, independent living, and employment settings.

Digital HealthEdTechSaaS

Tom Keating(CEO & Founder)

Athena Environmental Sciences Incathenaes.com

Athena Enzyme Systems, a business unit of Athena Environmental Sciences, develops and manufactures tools and products to improve the production and recovery of proteins.

BiotechDeep Tech

ATS-MER, LLCatsmer.com
ATTAINMENT CO., INC.attainmentcompany.com
AUTOIMMUNE TECHNOLOGIES, LLCautoimmune.com

Autoimmune Technologies is a biomedical company that licenses and develops diagnostic and therapeutic technologies from Tulane University's School of Medicine.

BiotechHealthtechMedical DevicesNew Orleans, US

AUTOMATED PRECISION, INC.apisensor.com
BEHAVIORAL TECHNOLOGIES CONSULTING ORGANIZATION, INCbehavioralconsult.comSep 2015 · $1M

Behavioral Technologies Consulting Organization (BTCO) provides organizational and behavior management consultation, supervision, and training in applied behavior analysis (ABA) for ABA therapy providers, school districts, and supervisees pursuing Board Certified Behavior Analyst credentials.

Digital HealthHealthtechMental HealthBasehor, US

Dr. Linda Heitzman-Powell(Founder)Kimberly Becker(COO (Chief Operating Officer))Christopher Powell(Financial Officer)

BERTEC CORPbertec.com
BFE Acquisition Sub II, LLCbfe.com
BIO-ANALYTICS, INC.biomedware.com
BIOMEDICAL DEVELOPMENT CORPbiodevcorp.comin𝕏

BioDev Corp develops consumer health and skincare products, including Skincerity, an overnight breathable masque based on a patented technology, and iClean, an iodine-based mouth rinse.

BiotechConsumerDigital Health

Biomedical Research Models, Inc.brmcro.com
BOLDER BIOTECHNOLOGY INCbolderbio.com

Bolder BioTechnology develops long-acting protein therapeutics for hematological and endocrine disorders, cancer, infectious diseases, and acute radiation syndrome.

BiotechHealthtechMedical DevicesBoulder, US

Joe Cox(President)

BRIMROSE CORPORATION OF AMERICAbrimrose.comin

Brimrose designs and manufactures Acousto-Optic Tunable Filter (AOTF) components, NIR spectrometers, and hyperspectral imagers, offering custom optical solutions.

Deep TechHardwareSpace Tech

C-MOTION, INC.c-motion.com
Caelum Research Corporationcaelum.com
Cathbuddycathbuddy.comSep 2020 · $675K

CathBuddy develops a reusable intermittent catheter system for people with spinal cord injuries and other catheter users, aiming to reduce single-use catheter waste and support patient independence.

HardwareHealthtechMedical DevicesWoodbury, US

Souvik Paul(CEO)Daniel Wollin(Director)John Neamonitis(Director)

Co-investorsHealth Wildcatters

CBT4CBT LLCcbt4cbt.com

CBT4CBT is a self-guided, web-based program that uses videos and interactive exercises to teach cognitive and behavioral skills for people managing drug or alcohol use disorders.

Digital HealthMental HealthWellness & Fitness

Kathleen Carroll(Lead Developer)

CERANOVA CORPceranova.com

CeraNova Corporation develops advanced ceramic components and high-strength and optical materials, offering engineering expertise and process and product development for demanding, high-specification applications.

Advanced ManufacturingDeep TechNew Materials

CFD RESEARCH CORPORATIONcfd-research.comin

CFD Research is a private company recognized on the Inc. 5000 list of America's fastest-growing private companies.

Deep Tech

CHARMTECH LABS LLCcaptivoice.cominSep 2015 · $1.3M

Capti ReadBasix is a diagnostic reading assessment for secondary students (grades 3-12) that identifies the root causes of reading difficulties through six individual subtests, benchmark reporting, Lexile measures, and dyslexia risk screening.

EdTechSaaS

Chemica Technologies, Incchemica.com
CHI SYSTEMS INCchisystems.com
CIENCIA INCciencia.com

Ciencia Inc. develops the Centinela diagnostic platform, which performs dozens of point-of-care medical tests from fingerstick or venous samples with results in under 30 minutes.

BiotechDigital HealthMedical Devices

CLEVELAND MEDICAL DEVICES, INC.clevemed.comin𝕏

CleveMed develops portable devices and fulfillment services for home sleep disorder testing, including monitors for home sleep apnea testing.

Digital HealthHealthtechMedical Devices

Closed Caption Latina, Corporationdicapta.comin𝕏

Dicapta produces media accessibility assets such as captions, dubbing, and video description in English, Spanish, French, and Portuguese, and develops accessibility technologies.

Impact & Social GoodMedia & Entertainment

COMBUSTION SCIENCE & ENGINEERING, INC.csefire.com

Combustion Science & Engineering, Inc.

CleantechDeep TechEnergy

Compact Membrane Systemscompactmembrane.cominNov 2025 · $3.3M

New Castle, US

Erica Nemser(Executive Officer, Director)inBill Charlton(Executive Officer)Bennett Nemser(Director)

BoardGuido Radaelli(Director)Chris Erickson(Director)Tony Sun(Director)

Co-investorsChevron Technology VenturesPangaea Ventures

CONTINUUM DYNAMICS INCcontinuum-dynamics.comin

Continuum Dynamics Inc is a research and development firm serving government and industry, providing analysis, software R&D, and testing across fields such as rotorcraft, flight simulation, nuclear engineering, and numerical methods.

Deep TechDefense TechEnergy

CorTechs Labscortechslabs.comMay 2020 · $1M

San Diego, US

Anders Dale(Director)Chris Airriess(Executive Officer, Director)Guri Stark(Executive Officer, Director)Nathan White(Executive Officer, Director)Thomas Barich(Executive Officer)Paul Mirabella(Director)

CREARE LLCcreare.cominAug 1997 · $7.3M

Creare is an engineering research and development firm that solves complex technical problems and develops new technologies for industry and government customers.

Deep TechHardwareSpace Tech

Dr. Jay Rozzi(Senior Staff)Jeff Breedlove(Senior Staff)Dr. Odile Clavier(Senior Staff)Dr. Patrick Magari(Senior Staff)

Creative Action LLCcreativeactionllc.com
CREATV MICROTECH INCcreatvmicrotech.com

Creatv is a company with three divisions: a microfabrication and electroplating services unit, a cancer diagnostics research division (Creatv Bio) that uses CellSieve microfilters to isolate and image cancer-associated cells from blood, and LifeTracDx, which offers diagnostic blood testing through a CLIA-certified laboratory.

BiotechHardwareMedical Devices

CRYOMAGNETICS INCcryomagnetics.comin𝕏

Cryomagnetics designs and manufactures superconducting magnets, cryostats, cryogenic accessories, and related electronic instrumentation in-house.

Advanced ManufacturingDeep TechHardware

CYBERNET SYSTEMS CORPORATIONcybernet.com

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4 more tracked companies

VORTANT TECHNOLOGIES LLCWESTEST ENGINEERING CORPXIA LLCZyrobotics

Exits · 1

IPOs and acquisitions across the tracked portfolio

CEL SCINYSE: CVM

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