Department of Health and Human Services — Full Portfolio

3C Institute builds custom technology and digital health software for researchers, educators, program developers, and clinicians, supporting the development and delivery of research-based programs.

Digital HealthEdTechHealthtech

ADA Technologies is a Colorado-based manufacturing company with an R&D division that develops, manufactures, and delivers customized products for advanced market customers.

Advanced ManufacturingDeep TechHardware

Adaract develops ultra-compact fluid power components, including pumps, valves, and actuators, aimed at enabling mobility applications.

Deep TechHardwareMobility & Transportation

Adelphi Technology manufactures neutron generator products, including deuterium-tritium, deuterium-deuterium, and thermal (moderated) neutron sources with yields ranging from 10^7 to over 10^10 neutrons per second.

Advanced ManufacturingDeep TechHardware

ALT LLC engineers materials, structures, and on-device AI for robots, prosthetics, drones, and autonomous systems, combining synthetic tissues, high-strength composites, additive manufacturing, and edge machine learning.

AI & Machine LearningNew MaterialsRoboticsSanta Barbara, US

ASC develops global shutter flash LIDAR (gsf-LIDAR), a solid-state, non-scanning time-of-flight 3D imaging and ranging camera that produces distortion-free point clouds for optical navigation, mapping, and situational awareness.

AI & Machine LearningDeep TechHardware

Advanced Targeting Systems develops research reagents including saporin-based targeted toxins, pHast Conjugates for internalization assays, ZAP kits, and secondary antibodies.

BiotechHealthtech

Aeon Imaging develops medical and scientific imaging technology, using confocal imaging based on the electronic aperture of CMOS sensors.

HardwareHealthtechMedical DevicesBloomington, US

Ann Elsner(Founder)

Aerodyne Research develops research-grade scientific instrumentation and provides measurement and R&D services focused on environmental and energy challenges.

Climate TechDeep TechHardware

AASC develops electric propulsion systems for satellites that generate thrust by ionizing solid metallic puck fuel (its Metal Pulsed Thruster), avoiding fluids, tanks and heaters.

Deep TechHardwareSpace Tech

Altec develops human sensing and measurement technologies for applications in health science, operational security, and human performance.

Deep TechHardwareHealthtech

Carlo De Luca

BiotechWatertown, US

Michael Easterling(Director)Kenneth Rothschild(Executive Officer, Director)John Gillespie(Executive Officer, Director)Peter Finn(Executive Officer)Brian Rothschild(Director)

Analatom builds hardware and software for automated inspection and condition monitoring of high-value assets such as aircraft, bridges, vehicles, pipelines, ships, and wind turbines.

AI & Machine LearningHardwareIoT

Analytical Instrument Systems (AIS, Inc.) designs and supplies voltammetric electrochemical instruments for analyzing environmental conditions in extreme settings, from deep oceans to polar regions.

CleantechClimate TechHardware

Anasphere, Inc. manufactures aerospace systems, including atmospheric sensors and inflation gas generators used in aviation testing, atmospheric research, and gas inflation applications.

Advanced ManufacturingHardwareLogan, US

RAMAS by Applied Biomathematics develops ecological risk software and offers consulting in risk analysis, predictive analytics, and specialized analytical methods for environmental and ecological problems.

AI & Machine LearningCleantechClimate Tech

Ashwin-Ushas develops advanced materials and devices including IR-electrochromic variable-emittance skins for spacecraft thermal control and dynamic camouflage, wide-temperature ionic-liquid Li-ion batteries, electrochemical sensors for chemical agents and hazardous compounds, microwave-based medical waste remediation, and electrochromic eyewear.

Deep TechNew MaterialsSpace Tech

Cognitopia offers web-based self-management and executive functioning software used to set goals, track assignments and progress, and maintain communication for individuals in special education, independent living, and employment settings.

Digital HealthEdTechSaaS

Tom Keating(CEO & Founder)

Athena Enzyme Systems, a business unit of Athena Environmental Sciences, develops and manufactures tools and products to improve the production and recovery of proteins.

BiotechDeep Tech

Autoimmune Technologies is a biomedical company that licenses and develops diagnostic and therapeutic technologies from Tulane University's School of Medicine.

BiotechHealthtechMedical DevicesNew Orleans, US

Behavioral Technologies Consulting Organization (BTCO) provides organizational and behavior management consultation, supervision, and training in applied behavior analysis (ABA) for ABA therapy providers, school districts, and supervisees pursuing Board Certified Behavior Analyst credentials.

Digital HealthHealthtechMental HealthBasehor, US

Dr. Linda Heitzman-Powell(Founder)Kimberly Becker(COO (Chief Operating Officer))Christopher Powell(Financial Officer)

BioDev Corp develops consumer health and skincare products, including Skincerity, an overnight breathable masque based on a patented technology, and iClean, an iodine-based mouth rinse.

BiotechConsumerDigital Health

Bolder BioTechnology develops long-acting protein therapeutics for hematological and endocrine disorders, cancer, infectious diseases, and acute radiation syndrome.

BiotechHealthtechMedical DevicesBoulder, US

Joe Cox(President)

Brimrose designs and manufactures Acousto-Optic Tunable Filter (AOTF) components, NIR spectrometers, and hyperspectral imagers, offering custom optical solutions.

Deep TechHardwareSpace Tech

Aurie manufactures a reusable catheter system designed for individuals who require catheterization, featuring a no-touch catheter and personal disinfector.

HealthtechMedical DevicesWoodbury, US

Daniel Wollin(Director)Souvik Paul(Executive Officer, Director)John Neamonitis(Director)

CeraNova Corporation develops advanced ceramic components and high-strength and optical materials, offering engineering expertise and process and product development for demanding, high-specification applications.

Advanced ManufacturingDeep TechNew Materials

CFD Research is a private company recognized on the Inc. 5000 list of America's fastest-growing private companies.

Deep Tech

Capti ReadBasix is a diagnostic reading assessment for secondary students (grades 3-12) that identifies the root causes of reading difficulties through six individual subtests, benchmark reporting, Lexile measures, and dyslexia risk screening.

EdTechSaaS

Ciencia Inc. develops the Centinela diagnostic platform, which performs dozens of point-of-care medical tests from fingerstick or venous samples with results in under 30 minutes.

BiotechDigital HealthMedical Devices

Dicapta produces media accessibility assets such as captions, dubbing, and video description in English, Spanish, French, and Portuguese, and develops accessibility technologies.

Impact & Social GoodMedia & Entertainment

Combustion Science & Engineering, Inc.

CleantechDeep TechEnergy

New Castle, US

Erica Nemser(Executive Officer, Director)Bill Charlton(Executive Officer)Bennett Nemser(Director)

BoardGuido Radaelli(Director)Chris Erickson(Director)Tony Sun(Director)

Continuum Dynamics Inc is a research and development firm serving government and industry, providing analysis, software R&D, and testing across fields such as rotorcraft, flight simulation, nuclear engineering, and numerical methods.

Deep TechDefense TechEnergy

San Diego, US

Nathan White(Executive Officer, Director)Chris Airriess(Executive Officer, Director)Thomas Barich(Executive Officer)Paul Mirabella(Director)Kong Han Tan(Director)Anders Dale(Director)

Creare is an engineering research and development firm that solves complex technical problems and develops new technologies for industry and government customers.

Deep TechHardwareSpace Tech

Dr. Jay Rozzi(Senior Staff)Jeff Breedlove(Senior Staff)Dr. Odile Clavier(Senior Staff)Dr. Patrick Magari(Senior Staff)

Creatv is a company with three divisions: a microfabrication and electroplating services unit, a cancer diagnostics research division (Creatv Bio) that uses CellSieve microfilters to isolate and image cancer-associated cells from blood, and LifeTracDx, which offers diagnostic blood testing through a CLIA-certified laboratory.

BiotechHardwareMedical Devices

Cryomagnetics designs and manufactures superconducting magnets, cryostats, cryogenic accessories, and related electronic instrumentation in-house.

Advanced ManufacturingDeep TechHardware

Detroit R&D develops and sells life-science research products including ELISA kits, antibodies, and antibody/protein/glycan microarrays for drug metabolism, cancer biomarkers, oxidative stress, mitochondrial function, and air pollution exposure.

BiotechHardwareHealthtech

Online gambling platform offering casino slots, live casino, lottery (togel), sports betting, poker, and arcade games, presented in Indonesian.

Doty Scientific designs and manufactures NMR probes and MRI radiofrequency coils, including solid-state NMR probes, PFG/diffusion Z-gradient probes, and high-field MRI volume and surface coils.

Deep TechHardwareMedical Devices

Dynaflow, Inc. provides research and development services and products in fluid dynamics and material sciences, specializing in bubble dynamics, cavitation, fluid-structure interactions, and erosion testing.

Deep TechHardwareNew MaterialsAnnapolis Junction, US

ENIG conducts theoretical and applied research in plasma physics, fusion science, energetic materials, and related fields, developing patented technologies such as electromagnetic gun systems, ground-penetrating radar, and soldier armor.

Deep TechDefense TechSpace Tech

Fischer Imaging develops diagnostic imaging products, continuing a long-standing legacy in the medical imaging field.

HardwareHealthtechMedical Devices

Flint Rehab makes FDA-listed neurorehabilitation devices and apps — including the FitMi full-body rehab tool, MusicGlove hand therapy, the Flex AFO foot-drop brace, and a speech and cognitive therapy app — for people recovering at home from stroke, brain injury, cerebral palsy, and other neurological conditions.

Digital HealthHardwareMedical Devices

FTI Defense builds a mission data platform combining data analytics, modeling and simulation, and generative AI tools — including the WOPR wargaming platform and an AI Sidekick application — to support military and defense operations.

AI & Machine LearningCybersecurityDefense Tech

Guild Associates develops engineered systems and adsorptive, reactive, and catalytic materials for applications including decontamination, chemical defense, and demilitarization.

Deep TechDefense TechNew Materials

Comply makes memory foam replacement ear tips for wireless earbuds and in-ear monitors, designed to improve fit, comfort, and hearing protection across more than 2,000 compatible devices.

ConsumerDirect to ConsumerHardware

HYPRES designs and commercializes superconductor integrated circuits and systems, including its Advanced Digital-RF Receiver and the ICE-T cryogenic test-bed, for government and commercial applications.

Deep TechHardwareSemiconductors

ISS develops scientific instrumentation for fluorescence and biomedical technologies, focusing on highly sensitive measurement devices.

BiotechHardwareMedical Devices

IBC develops and manufactures high-purity macrocycles and chelating agents (the MacroLig product line) and Molecular Recognition Technology (MRT) systems for highly selective metal separations.

Circular EconomyCleantechNew Materials

IBT (I-Biomed) is a biomedical company established in 1997 with roots at Johns Hopkins that has served over 5,000 patients and holds multiple patents and peer-reviewed publications.

BiotechHealthtechMedical Devices

Innovative Design Labs (IDL) is a research and development company that develops technology from concept to manufacturing, including medical training simulators, manikins, and non-contact health monitoring systems.

EdTechHardwareMedical DevicesMinneapolis, US

Inovati develops Kinetic Metallization, a low-pressure cold spray additive manufacturing process that deposits metals, ceramics, and polymers onto surfaces without melting the feedstock or substrate.

Advanced ManufacturingHardwareNew Materials

ILS (Integrated Laboratory Systems), now an Inotiv company, provides integrated, multidisciplinary toxicology services supporting research and regulatory compliance needs for clients.

BiotechHealthtech

IonOptix designs and manufactures precision life science instrumentation for preclinical and cardiovascular researchers, focused on studying isolated cardiomyocytes, muscle tissue, blood vessels and tissue culture.

BiotechHardwareMedical Devices

Trifoia provides online training and educational media services, including scenario-based explainer videos, digital course development, accessibility compliance, LMS hosting, and evaluative research.

EdTechFuture of WorkMedia & Entertainment

Advanced ManufacturingCosta Mesa, US

John J Stuart, Jr.(Director)James W Justice(Executive Officer, Director)John C. Carson(Executive Officer, Director)

Kalogon makes smart seating products, including a smart cushion using patent-pending sensor technology that continually adapts to the user to reduce sitting-related stress and protect health.

HardwareHealthtechMedical DevicesMelbourne, US

Tim Balz(Founder & CEO)Marcin Kubiak(Director)Mark Bergren(Director)Jeff Ready(Director)Aaron Jones(Co-Founder & Account Manager)Carla Borsoi(VP of Marketing & Research)

KamTek provides biorepository operations and laboratory services, including cryopreservation, cold-chain storage, sample processing, molecular biology, microbiology, and cellular services for biospecimens.

BiotechHealthtechLogistics & Supply Chain

The site publishes content on medical device development, including rapid prototyping for wearable MedTech and running clinical studies.

HardwareHealthtechMedical Devices

Learning Q provides life skills training through short, 2-5 minute video-based "skill units" that break complex concepts into manageable microlessons, with badging and certifications.

EdTechSaaS

Liberating Technologies, Inc.

Deep TechHealthtechMedical DevicesHolliston, US

Live & Learn, Inc. is a consultancy that partners with nonprofits, governments, and universities on participatory action research, offering grant writing, program design, R&D, and evaluation services in public health and social policy.

Future of WorkHealthtechImpact & Social GoodSan Luis Obispo, US

MandalMed is a biotechnology company developing therapies based on fibrosis research for patients with unmet medical needs.

BiotechHealthtech

Meadowlark Optics designs and manufactures polarization systems and components, including liquid crystal devices spanning UV to MWIR, with products such as shutters, rotators, waveplates/retarders, spatial light modulators, tunable optical filters, polarizers and polarimeters.

Advanced ManufacturingDeep TechHardware

Tom Baur

MDLogix offers bhworks, a platform for schools and states that unifies six modules — behavioral and mental health, nursing, universal screening, attendance/truancy, Medicaid billing, and special education/IEP — under a single Multi-Tiered System of Supports framework.

Digital HealthEdTechMental Health

Metron builds data analytics, decision-support, autonomy, and sensor-processing software using probabilistic modeling, signal processing, AI, and data fusion.

AI & Machine LearningDeep TechDefense Tech

HealthtechDexter, US

Scott Merz(Executive Officer, Director)Rio Foster(Director)Catherine Schmidt(Executive Officer)Robert Bartlett(Director)Christopher Ball(Director)Robert Foster(Executive Officer, Director)

MO SCI develops and manufactures custom high-tech glass products, including glass microspheres, powders, ingots, and specialty glasses, for clients across industries ranging from aerospace to pharmaceuticals.

Advanced ManufacturingDeep TechNew Materials

Molecular Express provides formulation, protein production and purification, and analytical testing services for vaccine and therapeutic development, built around its Molecular GPS platform for targeted drug delivery, oncology, and vaccines.

BiotechDeep Tech

Molecular Targeting Technologies develops and sells specialty chemistry research products, including cell membrane labels, apoptosis labels, fluorescent dyes, click chemistry reagents, crosslinkers, and optical imaging agents.

BiotechDeep Tech

MTI Biotech develops research-backed products aimed at maintaining healthy, active lifestyles, with products tested at academic institutions.

BiotechWellness & Fitness

MTR (Membrane Technology and Research) designs modular membrane systems for industrial gas separation, including monomer and hydrogen recovery, LPG recovery, syngas upgrading, and CO2 removal from natural gas.

Advanced ManufacturingCleantechNew MaterialsNewark, US

NeuraLynx builds neural recording data acquisition and analysis systems, including its Digital Lynx multichannel recording and stimulation platform, telemetry systems, and portable acquisition tools.

Deep TechHardwareHealthtech

NeuroTechR3 makes R3THA, an AI-driven neurorehabilitation system that uses adaptive exergames and real-time biofeedback to improve gross and fine motor hand and arm function.

AI & Machine LearningDigital HealthMedical Devices

Nexceris develops custom catalysts and electrochemical materials for clean energy and advanced manufacturing applications, including sustainable aviation fuel pathways (Fischer-Tropsch, Methanol-to-Jet, Alcohol-to-Jet, and Power-to-Liquids).

CleantechEnergyNew Materials

NECi builds enzyme-based test kits for detecting nitrate, phosphate, and other contaminants in water quality, environmental monitoring, agriculture, and education settings, and also supplies custom recombinant enzymes in bulk.

AgTechBiotechCleantech

NorthWest Research Associates (NWRA) is a scientist-owned research organization conducting basic and applied research in the geophysical and space sciences.

Deep TechSpace Tech

ObjectiveEd builds digital learning tools for students who learn differently, including reading-fluency, life-skills, and blind/low-vision instruction apps used by families, schools, and community agencies.

AI & Machine LearningEdTech

Optra Edge is an integrated hardware and software platform for deploying edge AI applications, letting businesses run AI outside the cloud with remote provisioning, fleet monitoring, and chainable software "skills." It offers industry-tailored offerings for manufacturing, retail, transportation, and healthcare.

AI & Machine LearningHardwareIoT

Organix is a US-based contract research organization (CRO) specializing in organic and medicinal chemistry, offering custom synthesis, analytical services, and contract R&D with expertise in lipids, oligonucleotides, and polymer chemistry.

BiotechDeep TechNew Materials

Orthocare Innovations develops and commercializes prosthetic, orthotic, and rehabilitation technologies for people with physical disabilities and their care providers.

HealthtechMedical DevicesRobotics

Oxford Biomedical Research develops immunoassay kits, purified recombinant enzymes, and antibodies for measuring biomarkers such as cortisol, histamine, isoprostanes, and glutathione S-transferases.

BiotechDeep TechHealthtech

pathVu provides sidewalk mapping and assessment services that collect and analyze pathway condition data, producing GIS outputs to characterize walkability and accessibility.

Data & InfrastructureGovTechMobility & TransportationPittsburgh, US

Perceptronics builds artificial intelligence and machine learning systems designed to support human decision-making in uncertain or high-stress environments.

AI & Machine LearningDefense TechGovTech

Physical Sciences Inc.

Deep TechDefense TechNew Materials

Pison manufactures a wearable neural watch that measures cognitive and physiological performance by reading signals between the brain and muscles.

HardwareHealthtechWellness & FitnessBoston, US

Dexter Ang(Executive Officer, Director)John Croteau(Executive Officer, Director)Salil Patel(Director)

BoardJames Hunt(Director)David Cipoletta(Director)

Pressure Profile Systems (PPS) designs capacitive tactile pressure sensors and its Chameleon software, which converts raw pressure data into visualizations for mapping and measuring contact mechanics.

Deep TechHardwareIoT

Proportional Technologies (PTI) develops boron-coated straw detector technology as a replacement for Helium-3 in neutron detection.

Deep TechHardware

Q-Chem develops quantum chemistry simulation software for predicting the structure, reactivity, properties, and spectra of molecules and materials.

Deep TechNew MaterialsSaaS

Radiation Monitoring Devices (RMD) develops radiation detection, high-speed imaging, nuclear instrumentation, and non-destructive test equipment, including scintillator materials for gamma-ray and neutron detection.

Deep TechHardwareNew Materials

Results Group is a research organization that translates research into solutions and operates Motive Labs, working with university and government research collaborators including NIH, NIDILRR, DHA, CDMRP, MTEC, and the UK NHS-HRA.

Deep TechDefense TechHealthtech

RJ Lee Group is a scientific consulting firm and industrial forensics laboratory that provides materials and environmental testing, including petrographic analysis, chemical testing, and expert witness services.

CleantechDeep TechNew Materials

Scientific Systems develops AI-powered autonomy technology for defense applications, serving U.S. government, aerospace, and defense organizations.

AI & Machine LearningDefense TechRoboticsBurlington, US

Sendero Group developed accessible GPS software and navigation products for blind and visually impaired users, powering devices like BrailleNote and Braille Sense and turn-by-turn apps including Seeing Eye GPS and RNIB Navigator.

ConsumerHealthtechMobility & Transportation

Sensimetrics Corporation performs research, development, and consulting in human communication, focusing on speech, hearing, acoustics, and digital signal processing.

Deep TechHardwareHealthtech

Sequella is a clinical-stage pharmaceutical company developing antibiotics to treat drug-resistant bacterial, fungal, and parasitic infections, including tuberculosis, MDR-TB, XDR-TB, H. pylori, and C. difficile.

BiotechHealthtech

SINTX manufactures silicon nitride and other advanced ceramics, engineering medical- and industrial-grade materials for uses such as spinal implants, hip and knee joint prosthetics, and additive manufacturing.

BiotechMedical DevicesNew Materials

SpaceFactory (formerly AI SpaceFactory) builds robotic autonomous systems and 3D-printing technology that convert lunar regolith and other native feedstocks into stabilized, load-bearing surfaces and infrastructure for space and defense environments.

Construction TechRoboticsSpace Tech

Spectral Sciences, Inc.

Deep TechDefense Tech

SpringWear Technology develops a wearable, spring-powered hand exoskeleton for at-home stroke rehabilitation, aimed at restoring hand function.

Digital HealthHardwareMedical Devices

Stata is a statistical software suite used by analysts, researchers, and academics for reproducible statistical analysis, data visualization, data management, and automated reporting.

AI & Machine LearningData & InfrastructureSaaS

Stottler Henke builds artificial intelligence software systems and provides consulting for applications including education and training, planning and scheduling, decision support, knowledge management, and autonomous systems.

AI & Machine LearningEnterprise SoftwareGovTech

STI Aerospace provides flight controls, modeling, simulation, pilot assessment, and training solutions for government and industry partners in the aerospace sector, with a focus on incorporating human factors into system design and engineering.

Deep TechDefense TechHardware

TDA Research Inc. is a research and development company that develops commercial products and technologies across the defense/aerospace, medical, materials, and energy industries, bringing them to market through direct sales, distribution agreements, spin-off companies, and licensing.

Deep TechEnergyNew MaterialsGolden, US

TA&T develops and manufactures advanced ceramic materials, including transparent Spinel ceramic armor, electro-optical windows, ceramic composites, and coatings, for aerospace, defense, industrial, automotive, and medical applications.

Advanced ManufacturingDeep TechNew Materials

Provides secure processing technologies for mission-critical aerospace and defense systems, including FPGA-based cryptography, secure boot, and physical protection (BuiltSECURE) hardware and IP solutions.

CybersecurityDefense TechHardware

Thornton Tomasetti applies engineering and scientific principles to the design, construction and performance of buildings, offering services such as structural engineering, forensics, flood risk protection, building enclosure renewal, rigging engineering for live events, and sustainability/life-cycle material analysis.

Climate TechConstruction TechDeep TechNew York, US

Touch Graphics Inc designs products and exhibits that convey spatial information through the sense of touch, aimed at accessibility for people who are blind or visually impaired.

HardwareHealthtech

TPL, Inc. develops advanced dielectric materials, including ceramic nanopowders, ceramic capacitors, performance capacitor films, and nanocomposite dielectrics.

Deep TechHardwareNew MaterialsAlbuquerque, US

Tristan Technologies designs and fabricates custom and standard SQUID (superconducting quantum interference device) magnetometer systems for detecting weak magnetic signals, used in scientific laboratory research and medical biomagnetic imaging.

Deep TechHardwareMedical DevicesSan Diego, US

Ultramet develops and manufactures refractory metals, platinum group metals, and ceramics—including coatings, freestanding structures, open-cell foams, and ceramic matrix composites—for use in extreme, high-performance environments.

Advanced ManufacturingDeep TechNew Materials

United States Drug Testing Laboratories (USDTL) is a forensic drug testing laboratory offering standard and customized drug screening panels.

BiotechHealthtech

Valar Systems designs and manufactures WiFi, Thread, and Zigbee stepper motor controllers and related electronics devices, sold through an online shop.

HardwareIoT

Daniel(Founder)

Vcom3D develops mixed reality medical simulation and training systems that integrate physical manikins and part-task trainers with virtual patients, anatomical overlays, and virtual medical equipment.

EdTechHealthtechMedical Devices