Mental Health Startups

PYM sells amino acid and nutrient supplements formulated to help the brain manage stress and support mood by promoting serotonin, dopamine, and oxytocin. The products are marketed to consumers as a daily "mental hygiene" routine for stress and mental wellbeing.

5 investors

Replika is an AI companion app that engages users in conversations and provides emotional support through memory, personality customization, and features like voice calls and messaging. The platform serves individuals seeking connection, emotional processing, and personal growth through AI-powered conversations.

5 investors

Seaport Therapeutics develops therapeutics and medicines. The company is led by a founder with extensive experience building biotech platforms and advancing novel drug development programs.

5 investors

Talkspace is an online mental health care platform that provides research-backed therapy and psychiatric services covered by insurance, allowing users to connect with licensed therapists and psychiatrists through text, audio, or video.

5 investors

Tava Health provides a platform connecting patients to mental health therapists with scheduling and practice management tools for providers. The service targets patients, employers offering mental health benefits, and mental health providers seeking practice management solutions.

5 investors

TRIP designs functional beverage and supplement products formulated with botanical ingredients intended to help users manage stress, improve sleep, and support overall wellbeing. The company targets consumers seeking natural products for daily mental health and relaxation support.

5 investors

Yana is a mobile app offering a supportive companion for emotional wellbeing and self-reflection, used by consumers seeking emotional support. It is positioned as a complement to, not a substitute for, professional mental health care.

5 investors

YourPath provides person-centered care for substance use disorders, connecting patients to peer recovery specialists, nurse practitioners and counselors via text and a technology platform. It serves patients in Minnesota with medical, clinical, and recovery support services across their recovery journey.

5 investors

Amae Health operates in-person outpatient clinics providing integrated care for people with complex and serious mental health conditions, combining psychiatry, therapy (CBT/DBT), primary care, nutrition, and peer support. It partners with academic medical centers and health systems to apply precision medicine and data analysis to treatment of serious mental illness (SMI).

4 investors

Boulder provides medication-assisted treatment for addiction through licensed specialists who prescribe buprenorphine, supported by dedicated care teams offering medical care, peer recovery coaching, and care coordination accessible via a digital platform.

4 investors

Cartwheel delivers evidence-based mental health and clinical care services to students and families through partnerships with school districts. The company uses technology to support its mission of providing organized and professional mental health services within school communities.

4 investors

Colla Health provides a behavioral health program for cancer patients, staffing clinicians with psycho-oncology training who deliver evidence-based therapies such as CBT and ACT. It serves community oncology practices and cancer centers across the United States.

4 investors

DiveThru provides mental health support through in-person studios and an online platform, offering therapy and psychological assessments. The company serves individuals seeking mental health care with an emphasis on accessibility and personalized matching with clinicians.

4 investors

evolvedMD integrates behavioral health services into primary care settings to improve access to mental health treatment. The company serves primary care practices and their patients seeking integrated care for depression, anxiety, and other mental health conditions.

4 investors

Flow develops technology-based mental health solutions to address depression symptoms and wellness. The company serves individuals seeking mental health treatment through science-backed approaches.

4 investors

Flowly provides a virtual clinic platform using VR and guided sessions to help employees manage nonstructural pain and related conditions including anxiety, depression, and sleep disorders. The offering combines immersive relaxation training, breathwork, support groups, and educational workshops for workplace wellness.

4 investors

Healium is an immersive wellness platform that pairs VR with real-time biometric data such as EEG brainwaves and heart rate to give clinicians measurable, drug-free tools for managing patients' stress, anxiety, and pain. It serves therapists, hospitals, and VA programs in the mental healthcare field.

4 investors

HelloSelf creates a platform that connects therapists and members to facilitate mental healthcare relationships. The company partners with healthcare providers to improve access to mental health services.

4 investors

Mindler (previously ieso) provides one-to-one, therapist-delivered text-based cognitive behavioural therapy (CBT) delivered online to patients, using de-identified therapy data and analysis to inform treatment. It offers mental health treatment for conditions such as anxiety, depression and sleep problems, available free to many NHS patients across the UK.

4 investors

Intellispark provides a platform for K-12 schools that helps educators, administrators, clinicians, and families track and coordinate student support around academic performance, behavior, and mental health. It offers tools for polling staff and students, recognizing positive behavior, and initiating referrals to address issues before they become crises.

4 investors

Journey provides a proactive workplace mental health program designed to identify and address employee mental health risks earlier than traditional employee assistance programs, reducing costs and preventing escalation.

4 investors

Koa Health develops a unified digital mental health platform that delivers evidence-based treatment programs and clinical interventions. The company serves healthcare organizations, medical institutions, and patients seeking comprehensive mental health care validated through randomized controlled trials and clinical research.

4 investors

Komodo Wellbeing publishes content on fostering a growth mindset and building resilience in students within the school environment. It appears focused on student wellbeing and educational resources for schools.

4 investors

Lissun is a tech-enabled mental and emotional health company offering online counselling and therapy to individuals and corporate clients in India. It integrates mental health support into mainstream healthcare across multiple categories and serves clients in cities across the country.

4 investors