Mental Health Startups

Unmind provides a mental health care platform for organizations, combining therapy, coaching, manager training, and learning tools to support employee wellbeing and prevent mental health crises. The platform serves corporate clients seeking to integrate mental health support into their workplace operations.

6 investors

Woebot is a chat-based mental health support app for adolescents that uses conversational AI informed by cognitive behavioral therapy and other evidence-based approaches. It provides on-demand access to mood tracking, journaling, mindfulness tools, and supportive techniques between clinical visits.

6 investors

AbleTo provides in-person and virtual mental health care, including therapy, psychiatry, and medication management for adults, children, and teens dealing with concerns such as anxiety, depression, ADHD, and substance use. It operates 150+ locations across the United States with over 1,200 therapists and psychiatrists, and accepts most insurance plans.

5 investors

Affect Therapeutics operates an app-based digital treatment provider offering care for substance use disorders (alcohol, cannabis, opioid) and mental health conditions like depression and anxiety, using methods such as contingency management, CBT, medication-assisted treatment, and peer support. It serves members across the U.S. including those covered by Medicaid, and works with providers, courts, employers, and health systems.

5 investors

Anise Health provides culturally responsive therapy and coaching for the Asian American and broader BIPOC community, using an evidence-based clinical care model. It works with a network of providers and commercial insurance partners to deliver mental health care tailored to underserved communities in the US.

5 investors

Hello Backpack provides mental health therapy and coaching services for children, teens, and young adults. The company offers play-based therapy for younger children, supportive counseling for adolescents, and care focused on self-discovery for young adults.

5 investors

Behavidence offers a patented mobile app that uses digital phenotyping and machine learning to passively track phone behavior and generate a daily Mental Health Similarity Score reflecting mood, focus, worry, and stress. It serves healthcare providers, clinical trials, insurance companies, and individuals, and administers validated questionnaires such as PHQ-9, GAD-7, and ASRS.

5 investors

Birches Health provides confidential virtual treatment for people struggling with gambling, sports betting, or trading addictions. Its clinical program was designed by specialists in gambling-specific care and delivers personalized treatment remotely.

5 investors

Blue Fever is a social platform designed for young people to express themselves and find mental health support through private AI conversations, group journaling, and peer support communities. The app helps teens navigate mental health challenges by creating a safe, moderated space that prioritizes emotional relevance and positive peer connection.

5 investors

Breathwrk is a mobile health and wellness app offering over 50 guided breathing exercises and coach-led classes designed to help users manage stress, focus, improve sleep, and boost athletic performance. It serves individual consumers across use cases such as calming, energizing, sleep, and performance.

5 investors

Feel Therapeutics develops digital biomarkers and digital health solutions for mental health treatment, designed to function as standalone programs or alongside medications. The company operates within the digital precision medicine space and partners with pharmaceutical and biotech firms on clinical development and commercialization.

5 investors

Finni matches families and children with autism spectrum disorder with ABA (Applied Behavior Analysis) therapy providers in their local area. The platform serves as a marketplace connecting patients with licensed care providers and works with insurance to make therapy accessible.

5 investors

Genoa Healthcare operates full-service pharmacies located inside mental health and community clinics, offering medication management for people with complex needs. It serves consumers with mental health conditions, assisted living residents, and those treating or preventing HIV/AIDS across pharmacies in 48 U.S. states and D.C.

5 investors

Sensate is a non-electrical wellness device and companion app that uses low-frequency vibration ("Somacoustics") and synchronized soundscapes placed on the chest to stimulate the vagus nerve and reduce stress, anxiety, and improve sleep. It is a consumer wellness product for people seeking relaxation and better sleep without medication or meditation technique.

5 investors

Inner Cosmos develops a minimally invasive brain-computer interface, described as a "digital pill," aimed at treating depression. The company has run an FDA-approved clinical trial for depression and publishes research on its neurotechnology.

5 investors

Intellect provides mental health support solutions for workplaces and individuals, offering employee assistance programs combined with self-care platforms and coaching/therapy sessions. The company serves corporate employers and individuals seeking mental wellbeing support.

5 investors

Journey is an Employee Assistance Program (EAP) that combines predictive analytics, personalized outreach, and a clinical network — powered by its Journey Signal AI engine — to detect employee mental health risk early and provide proactive care. It serves organizations seeking to support their workforce's mental health before issues escalate to crisis, operating globally.

5 investors

Lycos PBC develops investigational psychedelic-based therapeutics to treat mental health conditions, with an initial focus on post-traumatic stress disorder. The company applies decades of evidence-based research to create new therapeutic approaches for patients with unmet mental healthcare needs.

5 investors

Manatee provides a mental health platform designed for families, offering care that addresses the needs of both children and parents. The platform aims to improve family connection and child resilience through modern, accessible mental health services.

5 investors

Mightier develops technology to help children build emotional regulation and resilience skills. The company serves children and families through digital tools designed to improve emotional health and wellbeing.

5 investors

Mindbloom delivers guided ketamine therapy for depression and anxiety through a technology-enabled platform pairing clinicians with patients. The company serves individuals seeking science-backed mental health treatment in the United States.

5 investors

Motivo provides clinical supervision and support services for newly graduated therapists entering the mental health workforce, helping behavioral health organizations address the shortage of qualified mental health providers.

5 investors

NeuroFlow builds behavioral health integration platforms that identify population behavioral health risk, engage individuals with acuity-specific resources, and give care teams data to make decisions. It serves healthcare organizations and health systems aiming to improve outcomes and lower total cost of care.

5 investors

OurRitual offers personalized relationship support through live sessions with licensed therapists combined with digital tools including exercises, educational content, and AI-powered reflection features. The platform serves couples and individuals seeking to improve communication, repair disconnection, and build healthier relationships outside of traditional therapy settings.

5 investors