Mental Health Startups

Insite Health provides behavioral health programs for K-12 school communities, coordinating care among students, families, schools, and providers through expert teams, staff and parent workshops, training, and technology. The company combines clinical care, care coordination, and data analytics to improve mental health outcomes for students across the US.

6 investors

Kintsugi develops voice biomarker AI that analyzes short speech samples to detect and measure the severity of behavioral health conditions, integrating into clinical workflows and call centers for health systems and insurers. It also connects individuals to mental health resources and offers a consumer voice-journaling app for self-tracking.

6 investors

Little Otter provides whole-family mental health care, offering online therapy, psychiatry, and parent coaching for children and parents delivered by licensed clinicians via video and phone. It uses a family mental health assessment to tailor care plans, serves families across the US, and accepts insurance as well as out-of-pocket payment.

6 investors

MD Hub develops AI-powered tools for clinical workflows designed to earn clinician trust through technical rigor and practical integration into healthcare delivery processes. The company focuses on reducing clinical burden while maintaining care quality.

6 investors

Mightier develops technology to help children build emotional regulation and resilience skills. The company serves children and families through digital tools designed to improve emotional health and wellbeing.

6 investors

OncoHealth develops software and services to help health plans, employers, and oncologists manage cancer care and reduce treatment complexity. The platform combines oncology management tools with nursing, mental health, nutrition, and navigation services for patients and health systems.

6 investors

Ophelia provides telemedicine-based treatment for opioid addiction, offering online doctor's visits, withdrawal medication prescriptions, and long-term recovery support in place of in-person rehab. It uses medication-assisted treatment (MAT) to serve people recovering from opioid use disorder in the United States.

6 investors

Quartet Health provides a value-based behavioral healthcare solution that identifies, engages, and cares for patients with behavioral health needs, including serious mental illness. It serves health plans, health systems, and community mental health centers across 39 U.S. states and is now owned by NeuroFlow.

6 investors

Reframe is a digital habit-change program that helps users reduce or eliminate alcohol consumption through science-based methods. The app provides personalized information and tools for individuals seeking to change their relationship with alcohol.

6 investors

Luka is a software development company that builds AI-powered chatbot apps, including a messenger assistant and Replika, an AI companion app designed to help people cope with loneliness. The company uses its own deep learning architecture to power conversational AI friends.

6 investors

Seaport Therapeutics develops therapeutics and medicines. The company is led by a founder with extensive experience building biotech platforms and advancing novel drug development programs.

6 investors

Yana is a mobile app offering a supportive companion for emotional wellbeing and self-reflection, used by consumers seeking emotional support. It is positioned as a complement to, not a substitute for, professional mental health care.

6 investors

YourPath provides mental health counseling, substance use disorder treatment, peer support, and telehealth services, including on-demand assessments, individual therapy, and group sessions. It serves individuals dealing with stress, anxiety, depression, and substance use, with services available in Kentucky.

6 investors

Alli Connect provides customized mental health technology solutions designed for first responders to reduce stigma and enhance psychological resilience. The company offers programs, AI-driven therapist matching, and peer connection tools specifically for law enforcement and public safety personnel.

5 investors

Behavidence Enterprise is a clinical decision support platform that uses digital biomarkers to help healthcare professionals make diagnostic and treatment decisions.

5 investors

Colla Health provides a behavioral health program for cancer patients, staffing clinicians with psycho-oncology training who deliver evidence-based therapies such as CBT and ACT. It serves community oncology practices and cancer centers across the United States.

5 investors

Feel Therapeutics develops digital biomarkers and digital health solutions for mental health treatment, designed to function as standalone programs or alongside medications. The company operates within the digital precision medicine space and partners with pharmaceutical and biotech firms on clinical development and commercialization.

5 investors

Flow develops technology-based mental health solutions to address depression symptoms and wellness. The company serves individuals seeking mental health treatment through science-backed approaches.

5 investors

Genoa Healthcare operates full-service pharmacies located inside mental health and community clinics, offering medication management for people with complex needs. It serves consumers with mental health conditions, assisted living residents, and those treating or preventing HIV/AIDS across pharmacies in 48 U.S. states and D.C.

5 investors

Kanjo is a mental health platform that matches families with personalized care options, specialists, and clinicians through an AI-driven assessment system. The service helps parents and clinicians understand children's mental health and provides tools like affordability calculators and appointment scheduling.

5 investors

KeyWise AI develops Skye, an iPhone keyboard app that analyzes typing patterns using AI to generate a Clarity Score measuring cognitive function aspects like attention and processing speed. The product serves individuals seeking to track and understand their brain health and cognitive performance over time.

5 investors

Koa Health develops a unified digital mental health platform that delivers evidence-based treatment programs and clinical interventions. The company serves healthcare organizations, medical institutions, and patients seeking comprehensive mental health care validated through randomized controlled trials and clinical research.

5 investors

MDLIVE is a telehealth service offering 24/7 virtual medical appointments by phone or video with a national network of board-certified doctors, dermatologists, psychiatrists, and therapists. It provides urgent care, primary care, mental health, and dermatology services to patients across the United States and Puerto Rico.

5 investors

Meditopia provides holistic wellbeing programs that combine psychology, technology, and wellness to support mental, emotional, and physical health. It serves individual users as well as companies through customized wellbeing and Employee Assistance Program (EAP) offerings, operating across 60 countries.

5 investors