Jonathan Hirsch
InvestorPartner at Rebel Fund · Seed Investing at Kleiner Perkins
San Francisco Bay Area
Writes $100K – $5M checks · typically $1.5M
Find your path to Jonathan
996 people in our graph share verified history with Jonathan — schools, employers, funds. One of them is your warm intro.
Paul KwanunlockedJonathan: together at Stanford University (2007–2008)
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×2Jonathan: together at Stanford University
×2Jonathan: together at UCSF
×4Jonathan: together at Kleiner Perkins
About
Jonathan Hirsch is the founder and president of Syapse, a precision medicine company he started in 2008 that works with healthcare providers, life sciences companies, molecular diagnostics labs, and government agencies, contributing to the development of the precision medicine and oncology real-world evidence categories. He previously worked in neuroscience commercial development at Abbott Laboratories (now AbbVie), and holds an MSci in Neuroscience from Stanford University and an AB in Biology and Political Philosophy from the University of Chicago. He angel invests alongside his operating role and is affiliated with several funds, including the KPCB Seed fund.
Invests in
HealthtechMedical Devices
Experience
- ParadigmChief Strategy and Growth Officercurrent2022 — present
- Converge BioAdvisorcurrent2026 — present
- Rebel FundPartnercurrent2020 — present
- ProtegeSeed Investorcurrent2024 — present
- SleuthAdvisorcurrent2023 — present
- VitalizeSeed Investorcurrent2023 — present
- Empirical HealthSeed Investorcurrent2023 — present
- Synapticure Inc.Co-Founder, Investor, and Chair of the Advisory Boardcurrent2022 — present
- Arbital HealthInvestorcurrent2024 — present
- Solstice HealthSeed Investorcurrent2023 — present
- Oath SurgicalSeed Investorcurrent2023 — present
- FrameInvestorcurrent2021 — present
- Thyme CareInvestor and Advisory Boardcurrent2021 — present
- FortaInvestorcurrent2022 — present
- Viz.aiAdvisorcurrent2021 — present
- OsmindStrategic Advisor and Investorcurrent2020 — present
- FreenomeAdvisor, Real World Evidence & Data Platformcurrent2020 — present
- Rubicon FoundersSenior Advisorcurrent2021 — present
- VerifiableInvestorcurrent2020 — present
- Kleiner PerkinsSeed Investingcurrent2020 — present
- GBM AGILEChair, Data Committeecurrent2015 — present
- UCSFMember, Precision Medicine, Technology Advisory Groupcurrent2013 — present
- UCSFMentor, Digital Health, UCSF Lean Launchpad for Life Sciences and Healthcare2013 — 2015
- PaigeAdvisory Board2021 — 2023
- SyapseFounder and President2008 — 2021
- SXSWAdvisor Board Member, SXSW Interactive Accelerator2012 — 2017
- Free The DataSteering Committee Member2013 — 2016
- L.E.K. ConsultingAssociate2008
- Abbott LaboratoriesNeuroscience Commercial Development2007
- Avocet Polymer TechnologiesBusiness Development Manager2006
- University of Chicago Office of Technology and Intellectual PropertyIP Marketing Associate2005
- University of Chicago Medical CenterResearch Associate, Sangram Sisodia Laboratory, Department of Neurobiology2004
- Boston University School of MedicineResearcher, David Farb Laboratory, Department of Pharmacology & Experimental Therapeutics2001
Skills & more
Lifesciences43Biotechnology99Genomics67Molecular Biology43Bioinformatics32Entrepreneurship39Genetics28Semantic Technologies3Drug Discovery8Cell Biology9Cell Culture5Immunology2
+12 more
CancerBiochemistryOntologiesCommercializationDrug DevelopmentLaboratoryVenture CapitalBiomedical EngineeringEnterprise SoftwareOmicsPharmaceutical IndustryStrategyFrom Jonathan's professional profile.
Investments
Investor
Axle HealthDaybreak HealthOccamzRazorOsmindVerifiable
Per curated public sources.
Colleagues at Rebel Fund
Alexandra Espinal
Portfolio Development at Rebel Fund
Dan Siroker
Investor at Rebel Fund
Daniel Kan
Investor at Rebel Fund
Jared Heyman
Managing Partner at Rebel Fund
Justin Hilliard
Principal at Rebel Fund
Leslie Goldman Tepper
Founding Partner at The Artemis Fund
Luis Fortuño
Managing Director at Rebel Fund
Max Mullen
Investor at Rebel Fund
Network3
Adam BesvinickScout
Venture capital investor writing on early stage investing
Andrew MitchellScout
General Partner at Brand Foundry Ventures
Austin OgilvieScout
Angel investor
Investors connected to Jonathan in public investor directories — a warm-intro map.
Frequently asked questions
- Who is Jonathan Hirsch?
- Jonathan Hirsch is the founder and president of Syapse, a precision medicine company he started in 2008 that works with healthcare providers, life sciences companies, molecular diagnostics labs, and government agencies, contributing to the development of the precision medicine and oncology real-world evidence categories. He previously worked in neuroscience commercial development at Abbott Laboratories (now AbbVie), and holds an MSci in Neuroscience from Stanford University and an AB in Biology and Political Philosophy from the University of Chicago. He angel invests alongside his operating role and is affiliated with several funds, including the KPCB Seed fund.
- Where does Jonathan Hirsch work?
- Jonathan Hirsch is Partner at Rebel Fund.
- What does Jonathan Hirsch invest in?
- Jonathan Hirsch invests in Healthtech, Medical Devices.
- What check size does Jonathan Hirsch write?
- Jonathan Hirsch typically writes checks of $100K – $5M.
- What companies has Jonathan Hirsch invested in?
- Investments tracked here include Axle Health, Daybreak Health, OccamzRazor, Osmind, Verifiable.
- Where did Jonathan Hirsch go to school?
- Jonathan Hirsch studied at Stanford University (M.Sci., Biological Sciences); University of Chicago (A.B., Biology); Choate Rosemary Hall.
Founder mafias
Y Combinator mafia10,230
Also came through, then founded or led a company.
Sam AltmanPresidentFounded Tools for Humanity +3Garry TanPresident & CEOFounded Y Combinator +1Jessica LivingstonCo-founderFounded Y CombinatorAlexis OhanianPartnerFounded RedditFred EhrsamYC Summer 2012Founded Nudge +1Matt HuangYC Winter 2011Founded Paradigm +1
+ 10,223 more
Stanford University mafia1,932
Also came through, then founded or led a company.
Peter ThielJ.D.Founded PayPal +1Reid HoffmanB.S.Founded LinkedIn +2David SacksB.A.Founded YammerKeith RaboisB.A.Founded OpendoorGarry TanBSFounded Y Combinator +1Joe LonsdaleBSFounded Opto +5
+ 1,925 more
University of Chicago mafia191
Also came through, then founded or led a company.
Alexis BorisyBachelor's degreeFounded Foundation Medicine +2Bobby PittmanMaster's degreeFounded Oathafrica +2Sean HarperABFounded TransFS +2Bharat KilaruBachelor of Arts (BA)Founded Verano Health +2James Peyer, PhDBachelor of Arts (B.A.)Founded Rapalogix Health +2Matt KrisiloffFounded Preventive +1
+ 184 more
Kleiner Perkins mafia67
Also came through, then founded or led a company.
Eric RiesVenture AdvisorFounded LTSE Group +2Brook ByersFounderFounded Insite Vision +1Jonah GreenbergerEarly(ish)-stage investor / Kleiner-Perkins scoutFounded Bright Exchange +1Raphael RouvinovEngineering FellowFounded Luminopia +1Rebecca LeeKleiner Perkins FellowFounded Elayne +1Jesse HuEngineering FellowFounded Abundant +1
+ 60 more
SXSW mafia18
Also came through, then founded or led a company.
Malcolm OngPanel Liaison & Speaker & MentorFounded Terminal3 +1Joah SpearmanFounder & Executive Producer of Style XFounded Tenyour +1Keith KirklandPitch Advisory BoardFounded Wear +1Florin MihocAdvisory Board- (Pitch Competition)Founded Freight FarmsAngel GambinoSXSW Interactive Accelerator Advisory BoardFounded AngelgambinoRohun VoraWriter/DirectorFounded Duffl
+ 11 more
Same school
Also attended Stanford University2,000
Peter ThielCo-founder & Partner at Founders FundReid HoffmanCo-founder of LinkedIn; Partner at GreylockDavid SacksCo-founder & General Partner at Craft Ventures; former White House AI & Crypto CzarKeith RaboisManaging Director at Khosla VenturesGarry TanPresident & CEO of Y CombinatorAlfred LinPartner at Sequoia Capital
+ 1,994 more
Also attended University of Chicago529
Mark SusterManaging Partner at Upfront VenturesShardul ShahInvestor at Index VenturesSam BlackmanEntrepreneur in Residence at GV (Google Ventures)Clay FisherInvestor at Spark CapitalRolanda FuInvestor at Madrona Venture GroupJonas CiplickasPrincipal at Scale Venture Partners
+ 523 more
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