Overwater Ventures Llc — Full Portfolio

Adaptyx develops a minimally-invasive wearable dermal patch that continuously measures biomarkers in interstitial fluid using an array of programmable molecular switches.

BiotechDigital HealthMedical Devices

VSVijit Sabnis(Co-Founder & CEO)inAYAlex Yoshikawa(Co-Founder & Chief Science Officer)inPKPawan Kapur(Co-Founder & Chief Technology Officer)inHTH. Tom Soh(Co-Founder & Scientific Advisor)JMJoseph M. DeSimone(Co-Founder & Scientific Advisor)DGDaniel Grossman(Chief Medical & Business Officer)in

Co-investorsAIAIN VenturesHUHumba VenturesNENext VenturesSTStartXCHChemistryCRCraft Ventures+1 more

Apaluma builds a data platform for government regulatory agencies that ingests decades of scanned permits, filings, violations, and monitoring feeds and turns them into searchable, structured intelligence mapped to physical locations.

AI & Machine LearningGovTechSaaS

AJAlicia J. Keyes(Founder)in

Co-investorsCRCrosslink CapitalKIKickstartGRGrishin Robotics

BeSound provides radiation-free breast ultrasound imaging with AI-powered detection, aimed at women — particularly those with dense breast tissue — who may be underserved by mammography.

Digital HealthFemTechMedical DevicesLos Angeles, US

BRBailey Renger(Founder)

Co-investorsCOCorazon CapitalHYHyperplane Venture CapitalKIKindred VenturesMUMuse CapitalPAPave Health VenturesSSSSC Venture Partners+3 more

Certuma builds autonomous clinical infrastructure that combines LLM reasoning with deterministic verification to deliver physician-reviewed clinical decisions at scale, addressing the global physician shortage by validating clinical workflows as infrastructure for remote patient care.

AI & Machine LearningDigital HealthHealthtech

MVMartin Varsavsky(Chief Executive Officer)inACArmando Cuesta(Chief Medical Officer)JSJoe Scanlin(Chief Technology Officer)inJMJesus Mejia(Chief Legal Officer)inBMBruno Marino(Head of Digital Products)in

Co-investorsCHChemistryCRCraft VenturesPAPace Capital

Conceive offers a membership-based fertility support service that connects members with nurses and coaches available 24/7 via text for personalized coaching, help interpreting fertility testing, and guidance through trying to conceive, IVF, treatment, and pregnancy.

Digital HealthFemTechWellness & FitnessNew York, US

LBLauren Berson(Founder)in

Co-investorsEVEverywhere VenturesFOFounder CollectiveGRGreat Oaks Venture CapitalKIKindred VenturesMYMyelin VCCHChemistry+2 more

Feanix Autopilot is an AI-powered platform that combines whole-genome sequencing, farm performance data, and economics to provide herd-level breeding and culling recommendations for dairy farmers.

Advanced ManufacturingAgTechAI & Machine LearningAsheville, US

MAMitchell Angove(Founder)inTBTom Bishop(Founder)inMeia AlsupRuthy Anderson(Chief of Staff)

Co-investorsCOCollaborative FundINInitialized CapitalNONorth South VenturesY Y CombinatorANAndreessen HorowitzGEGeneral Catalyst+1 more

Fellow operates a CLIA-certified diagnostics lab offering mail-in semen analysis for vasectomy and fertility testing, delivering clinically valid results without an in-person lab visit.

Digital HealthHealthtechMedical Devices

Co-investorsGEGenoa VenturesGRGreat Oaks Venture CapitalHUHuman CapitalJOJovonoMAMantis CapitalMYMyelin VC+5 more

Hyfé operates a refining process that extracts specialty ingredients and chemical building blocks from food-processing waste and biomass.

Circular EconomyFoodTechNew MaterialsChicago, US

MRMichelle Ruiz(Executive Officer, Director)inAndrea Schoen(Executive Officer)

Co-investorsSYSynthesis CapitalCHChemistryCRCraft VenturesPAPace CapitalTHThe Engine Ventures

Olio Labs develops drug combination therapies using machine learning to identify treatments that target multiple interacting proteins simultaneously, with initial candidates focused on obesity treatment.

BiotechHealthtech

DTDavid Tingley(Founder)inTRTom Roseberry(Founder)inTim Krausz(Lead Research Engineer)

Co-investorsPIPioneerSCSciFoundersSCScrum VenturesY Y CombinatorZAZAKA VCBOBoom Capital

20tree.ai (operating as Overstory) provides AI-powered vegetation intelligence for electric utilities, combining satellite and aerial imagery with local asset data to optimize vegetation management programs.

AI & Machine LearningCleantechClimate TechEnergyEnterprise SoftwareInsurTechAmsterdam, NL

IDIndra den Bakker(Co-founder)inDPDoug Perrygo(CFO)inTMTamara Mendelsohn(COO)inBLBrian Lafayette(VP of Product & Strategy)inPDPeternille Dekker(Head of People)inFSFiona Spruill(CEO)in

Co-investorsB B Capital GroupB4B4 CapitalBEBentley iTwin VenturesCACapitalTCECerity Partners VenturesCOConvective Capital+18 more

Overture develops automation and technology to improve fertility treatment, aiming to lower costs and increase success rates.

BiotechFemTechHealthtechNew York, US

Santiago Munn?(Executive Officer, Director)MVMart?n Varsavsky(Executive Officer, Director)inSMSantiago Munnein

BoardVSVijit Sabnis(Director)in

Co-investorsEVEvolution VenturesGAGaingelsJAJazzya InvestmentsKHKhosla VenturesMAMana VenturesMYMyelin VC+2 more

Penguin is a Thai travel company whose booking app brings airfares held by local Southeast Asian travel agencies onto an online channel.

Travel & Hospitality

Kittikorn KunnalekhaTaxsa BunnagVachara AemavatZhaocheng(muyi) Fan(Founder)in

Co-investors50500 GlobalGRGreycroftHUHudson Structured Capital ManagementSNSnowflake VenturesSTStone PointWAWatershed Growth Ventures

Penguin Ai is an AI operating system for healthcare administration that deploys purpose-built "AI Workers" to handle tasks like prior authorization, eligibility checks, claims review, and medical coding while keeping humans in the loop.

AI & Machine LearningDigital HealthHealthtech

FBFawad Butt(Founder)in

Co-investorsGRGreycroftINInvariantes FundMAManchesterStory Group, LLCPLPlug and Play VenturesSESemperVirens Venture CapitalSNSnowflake Ventures

Platform.sh (Upsun) provides a cloud hosting platform for development teams that supports multiple runtime languages and frameworks with centralized control over security, compliance, and spend management.

Cloud ComputingDeveloper ToolsEnterprise Software

FPFred PLAIS(Founder)in

Co-investorsBGBGVISIsaiISISAI GestionOPOpenOceanYTYttriumCRCrosslink Capital+8 more

Reimagining how we source, produce and experience food

Dylan Nugent(Founder)in

Co-investorsJUJuniperNENext VenturesSTStartXSUSustainable Food Ventures

Quorum Bio develops genetic engineering tools for precision fermentation, enabling the production of complex natural products using engineered non-model microbes.

AgTechBiotechFoodTech

Sudharsan Dwarknath, Ph.D(Co-Founder & CEO)YYYasuo Yoshikuni, Ph.D(Co-Founder & Advisor)SDSudharsan Dwaraknath(Founder)in

Co-investorsAGAg Ventures AllianceCOCollaborative FundFTFTW VenturesJUJuniperCHChemistryCRCraft Ventures+1 more

RTHM combines artificial intelligence with clinical expertise to help patients with complex and unexplained illnesses find faster paths to diagnosis and treatment.

AI & Machine LearningDigital HealthHealthtechSan Francisco, US

RKRyan Kellogg(Founder)inJCJennifer Curtin(Founder)inMSMichael Snyder(Scientific Cofounder)inEBEduardo Bohrer(COO/CFO and Cofounder)in

Co-investorsY Y CombinatorKHKhosla Ventures

Scale Management operates an e-procurement platform that connects buyers with vetted suppliers, helping organizations across Africa digitize and automate their procurement workflows.

B2B MarketplacesEnterprise SoftwareFintechSaaSNairobi, KE

MTMarvin Tumbo(Co-Founder / CEO)inBMBrian Mung'ei(Co-Founder / COO)inCMComark Maloba(Co-Founder / CTO)

Co-investorsTETechstarsRERenew CapitalNANairobi Business Angel NetworkCACastrum CapitalCRCrosslink CapitalHAHAVEN VENTURES+7 more

tendercare is a free platform for family caregivers that organizes information, coordinates care, and connects users to vetted professional services for elder and adult care.

HealthtechImpact & Social GoodWellness & Fitness

SSShauna Sweeney(Founder & CEO)in

Co-investors181843 CapitalHAHannah Grey VenturesLOLowercarbon CapitalFUFullCircle

Tiny Health offers at-home gut and vaginal microbiome test kits with age-specific, evidence-based reports that recommend diet, supplement, and lifestyle changes.

Digital HealthHealthtechWellness & Fitness

CSCheryl Sew Hoy(Founder)in

Co-investorsALAlumni VenturesB B Capital GroupB4B4 CapitalCACartan CapitalDEDenver VenturesMOModi Ventures+12 more

Trial Library operates an AI-native platform that integrates clinical trials into routine care, activating providers, identifying eligible patients, and guiding them through the trial lifecycle.

AI & Machine LearningDigital HealthHealthtech

Co-investorsGAGaingelsHOHow Women InvestLULux CapitalNENext VenturesPLPlug and Play VenturesSASanofi Ventures+3 more

Zero Acre Farms produces cooking oils optimized for chefs and restaurants, using organic fera fruit oil as an alternative to seed oils with superior heat stability, cleaner taste, and healthier fat profiles.

AgTechConsumerFoodTechImpact & Social GoodSan Francisco, US

Jeff Nobbs(Founder)inAnthony Gustin(Founder)Steve Del Cardayre(Founder)

Co-investorsBOBoxGroupCOCollaborative FundCOCornucopian Capital ManagementDEDesigner FundFIFifty YearsFOFootPrint Coalition+11 more