How many investments has Northern Gritstone made?

Northern Gritstone has 37 tracked investments, 1 of which have exited, including 9 dated in the last 24 months.

What stage does Northern Gritstone invest at?

Northern Gritstone invests at the Pre-Seed, Seed, Series A, Series B, Series C, Growth stages.

Where is Northern Gritstone located?

Northern Gritstone is headquartered in Manchester, GB.

Does Northern Gritstone lead rounds?

Northern Gritstone typically participates in rounds rather than leading them.

Who does Northern Gritstone co-invest with?

Northern Gritstone most often shares deals with Future Planet Capital, IQ Capital, Octopus Ventures, among 28 tracked co-investors.

Northern Gritstone

Venture capital

Manchester · Pre-Seed–Growth · 41 people tracked

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1,937 people in our graph share verified history with the Northern Gritstone team — schools, employers, funds. One of them is your warm intro.

Stephan Dolezalekunlockedknows Gareth Llewellyn · together at Wheatsheaf Group Limited (overlapped)

knows the team · via AMEC

×2knows the team · via IP Group Plc

knows the team · via Newton Venture Program 2022

×4knows the team · via Northern Trust Corporation

×2knows the team · via University of Leeds

✨ Fox Verdict

Investment thesis

Northern Gritstone invests in science and technology companies emerging from the North of England, particularly university spinouts from the Northern Arc universities of Leeds, Manchester, Sheffield and Liverpool, as well as other early-stage regional businesses. It targets deep technology and life sciences companies with strong intellectual property and global ambitions, assessing opportunities on the strength of their teams, technology, market potential, and business models that deliver both profit and purpose. The firm positions itself as a patient, long-term partner able to support companies from early stages through to later growth, and provides wraparound support to build a regional innovation ecosystem. It operates under a core philosophy of 'profit with purpose.'

Invests inAI & Machine Learning Biotech Cleantech Deep Tech Energy Hardware Healthtech Impact & Social Good Longevity Medical Devices New Materials SaaS Semiconductors Europe Manchester United Kingdom

Source: firm website, verified Sep 27, 2026.

Stage

Pre-Seed–Growth

Manchester, GB

Leads rounds

Follows

Instruments

Equity

Founded

2020

Last 12 months

4 investments

Tracked investments

Acquisitions

Team · 41 people

from the firm's website & curated & public directories

Duncan Johnson· Chief Executive Officer· London, England, United Kingdomin

Chief Executive Officer who previously headed Caledonia Private Capital and was a founding partner at RJD Partners. Trained as a chartered accountant at PwC.

Simon Braham· Chief Investment Officerin

Chief Investment Officer and experienced private equity, growth and impact investor who joined from Bridges, with prior roles at LDC, JP Morgan Cazenove, Lloyds Banking Group and KPMG.

Narjeet Singh· Investment Manager

Investment Manager who joined from Lincoln International's Technology M&A team, with earlier valuations and M&A work at KPMG. ACA qualified with a First Class BSc in Economics from the University of Manchester.

Tom Kaye· Investment Manager

Investment Manager who joined from Anticus Partners, analysing early-stage technology companies via Finance Yorkshire funds. Holds the CFA IMC and is working toward ACCA.

Alison Maughan· Investment Manager· United Kingdomin

Investment Manager with corporate VC and life sciences experience, previously at Deepbridge Capital. Holds a BA in Biological Sciences from the University of Oxford.

Cassie Doherty· Investment Director· United Kingdomin

Investment Director specialising in life sciences spinouts, joined from Parkwalk Advisors with over two decades in university spinout ventures. Holds a PhD in Biochemistry from the University of Leeds.

Gareth Llewellyn· Investment Director· Sale, England, United Kingdomin

Investment Director and University of Sheffield engineering graduate who moved into early-stage tech investing with Grosvenor Food & AgTech and has held operational roles at portfolio companies.

James Gibbons· Investment Director· United Kingdomin

Investment Director with a background building and investing in deeptech startups and university spinouts, joined from Old College Capital. Previously led IP Licensing at the University of Leeds.

Khadija Ashfaq· Investment Director· Leeds, England, United Kingdomin

Investment Director who joined from Northstar Ventures, where she managed early-stage investments in AI, life sciences and technology across North-East England. Holds a BSc in Economics from the University of York and the CFA IMC.

Alex Macpherson· Independent Non-Executive Director

Independent Non-Executive Director and venture capitalist with over 25 years' experience, a venture partner at Isomer Capital and co-founder of the business that became Octopus Ventures.

Andrew Graham· Independent Non-Executive Directorin

Independent Non-Executive Director with over 30 years in financial services and technology, previously COO of Blippar and chairperson/NED of several fast-growing companies.

Andrew Naylor· Head of Origination

Head of Origination, previously CEO of Nottingham Technology Ventures, with over 17 years growing technology businesses. Holds a PhD in Physics from the University of Nottingham.

Ashleigh Barker· Personal Assistant

Personal Assistant who began her career at a boutique consultancy before joining Acuity Advisors as a Team PA.

Bill Cann· Associate, NG Innovation Servicesin

Associate in NG Innovation Services who joined after an MSc in Business Analysis and Strategic Management from the University of Manchester, with prior strategic consulting and tech startup experience.

Catherine Clarke· Consultant (Legal)in

Legal consultant and corporate lawyer with over three decades of experience, most recently as General Counsel at BGF, with earlier roles at 3i Group and Gowling WLG.

Claire Blackburn· Company Secretary and Compliance Officerin

Governance professional responsible for compliance procedures and policies, previously at Eversheds Sutherland, KPMG and Indigo Independent Governance. A Fellow of the Chartered Governance Institute.

Darran Ward· Independent Member of the Purpose and Impact Committee

Independent Purpose and Impact Committee member and Head of Alternatives at the West Yorkshire Pension Fund, overseeing a £1bn multi-asset platform. A CFA charterholder.

Ella Johnson· Personal Assistant, NG Innovation Services

Personal Assistant in NG Innovation Services with a background in healthcare and criminal justice, previously a Support Worker at Victim Support.

Eve Howarth· Co-Investor and Capital Manager

Co-Investor and Capital Manager overseeing relationships with the firm's co-investors, previously at Lazard and Deloitte. Holds a First Class BA in Economics from the University of Durham.

Fiona Marston OBE· Independent Member of the Investment Committeein

Independent Investment Committee member and biotechnology entrepreneur, currently Royal Society Entrepreneur in Residence at the University of Reading and CEO of Erebagen Limited.

Frances Garside· Executive Assistantin

Executive Assistant who joined from New Street Consulting and previously supported the CEO of Pure Gym. A University of Durham graduate and co-founder of a Yorkshire theatre company.

Gordon McAlpine· Growth Director, NG Innovation Servicesin

Growth Director in NG Innovation Services with over 30 years of entrepreneurial experience, co-founder of legal tech company BigHand and a bestselling author on scaling businesses.

Ieva Ruzgyte· Reporting Analystin

Reporting Analyst with finance experience, previously a Senior Finance Operations Analyst at Booking.com and analyst roles at Together.

James Bellis· Portfolio Director

Portfolio Director focused on value creation, with over 10 years advising companies through transactions, turnarounds and restructurings. Previously at Teneo, Interpath and KPMG; a Chartered Accountant with the ICAEW.

James Hadley· Chief Financial Officer

Chief Financial Officer and ICAEW Fellow with around 20 years in financial services, previously CFO/COO at Savannah, a tech-focused VC fund manager.

Jane Madeley· University Appointed Non-Executive Director

University-appointed Non-Executive Director and CFO of the University of Leeds, with earlier senior finance roles at ASDA Walmart, Campbell Soup Company and PPR.

Jessica Zoutsos· Investment Advisor

Investment Advisor and founder/CEO of Capitalex, a fundraising platform for UK businesses. A Goldman Sachs alumna and early BGF investment team member.

Joanne Hosker· Head of NG Innovation Servicesin

Head of NG Innovation Services and talent professional connecting early-stage businesses with entrepreneurs and operating partners, previously with BGF's Talent Network Team.

John Holden· University Appointed Non-Executive Director

University-appointed Non-Executive Director who has led major strategic innovation initiatives at the University of Manchester, including Unit M and the Cambridge x Manchester Innovation Partnership.

Juliet Livadiotis· Investment Advisor

Investment Advisor focused on seed/Series A biotechnology, previously involved with CMS Ventures and Oxford Biotherapeutics, and co-founder of Cambridge Gene Therapy.

Kate Spencer· Head of Communications & Marketingin

Head of Communications & Marketing with a background in financial services and climate technology, previously at BNP Paribas, Turntide Technologies and JP Morgan.

Keith Breslauer· Independent Member of the Purpose & Impact Committee

Managing Director of Patron Capital, which he founded in 1999 and which manages roughly €5 billion in European property investments. An active charity supporter.

Lord Jim O'Neill· Chairperson

Chairperson and cross-bench peer in the House of Lords, chair of the Northern Powerhouse Partnership, and former Goldman Sachs chief economist who coined the term BRIC.

Magda Wynne· Management Accountant

Management Accountant who joined from FOD Mobility Group, with an accountancy and finance background and the CIMA Diploma in Management Accounting.

Maire McKay· Talent Manager, NG Innovation Services

Talent Manager in NG Innovation Services working with leadership teams of early-stage tech companies, previously at BGF's Value Creation team and in executive search.

Niranjan Sirdeshpande· Non-Executive Director

Non-Executive Director and Global Head of M&G's Catalyst team, with experience originating early-stage equity and private debt transactions across biotech, fintech and clean energy.

Paddy Dowdall· Non Executive Director

Non-Executive Director and Assistant Director at Greater Manchester Pension Fund, with broad experience across listed securities, infrastructure, private equity and property.

Phoebe Bunton· Company Secretarial Assistant

Company Secretarial Assistant with a compliance background as an AML/KYC analyst at an offshore law firm. Holds a First-Class law degree and a master's in International Corporate Law from the University of Leeds.

Rosie Setchell-Hynes· Relationship Manager, NG Innovation Servicesin

Relationship Manager in NG Innovation Services with a professional services background, previously Business Development Executive at CMSPI.

Sallie Trenell· Personal Assistant

Personal Assistant who joined from Palatine Private Equity, an award-winning support professional recognised at the 2022 Manchester PA Awards.

Sue Hartley· University Appointed Non-Executive Director

University-appointed Non-Executive Director and Vice-President for Research at the University of Sheffield, overseeing research, innovation and commercialisation activities.

What they invest in

from 30 of 37 portfolio companies

Deep Tech ×19Hardware ×9AI & Machine Learning ×7Enterprise Software ×7Healthtech ×7Biotech ×6Cleantech ×6New Materials ×6

HQs:United Kingdom×22Singapore×1

Who they back

founder profiles across 11 portfolio companies

36%

solo founders

4 of 11 mapped founding teams

29%

repeat founders

of 14 founders with career history

Founding team size:solo founder×42 founders×43 founders×24+ founders×1

Where their founders studiedfrom 13 founders with education data

The University of Sheffield ×2University of Cambridge ×2

What their founders studiedfrom 14 founders with field-of-study data

Engineering ×7Computer Science ×3Physics ×2

Where their founders worked beforefrom 14 founders with career history

University of Leeds ×3Curvalux ×2Deeptech Labs ×2

Investments · 37 tracked

founders shown can be your intro path

By year:2026 · 3 2025 · 3 2024 · 5 2023 · 314 dated

Cavero Quantumcaveroquantum.com in✓ verified

Cavero Quantum develops software-based quantum-safe cryptographic solutions for cybersecurity.

CybersecurityIoTQuantum Computing

Frey Wilson(Co-Founder and CTO)in Ben Varcoe(Co-Founder, director and advisor)in

BoardJeremy Lewis(Chair)

Co-investorsForesight

Crucible Therapeuticscrucible-tx.com in✓ verified

Crucible develops RNA-based therapies targeting neurodegenerative diseases, leveraging research from the University of Sheffield's translational neuroscience institutes.

BiotechDeep TechHealthtechSheffield, GB

Cliff Holloway(Chief Executive Officer)in

Adsilicoadsilico.ukFeb 2024

adsilico builds generative AI technology that creates diverse virtual patient populations—digital models of human anatomy, physiology, and pathology—to run in silico trials that assess medical device safety and performance before human testing.

AI & Machine LearningHealthtechMedical Devices

Dr Nishant Ravikumar inDr Zeike TaylorinProf Alejandro FrangiSheena Macphersonin

Co-investorsParkwalk Advisors

Amplisiamplisi.com inMar 2026

AmpliSi develops porous silicon battery anode material using a proprietary silane-free, low-temperature magnesiothermic process that converts silica into high-energy silicon anodes to replace graphite in lithium-ion batteries.

CleantechEnergyNew Materials

Ruth Sayers(CEO)in

Co-investorsClean Growth Fund

Asset Coolassetcool.com in

AssetCool builds robotic systems, including its Capacity-1 line robots, that apply capacity-enhancing coatings to existing overhead power lines to increase grid capacity without lengthy outages or reconductoring.

CleantechEnergyNew MaterialsRobotics

Jasmin Stewart(Head of People)in Winter Wilson(Head of Marketing)inNiall Coogan(CEO)in

Co-investorsCarbon Elewit Energy Impact Partners Kero Development Partners Mercia Ventures Extantia Capital

Auxetecauxetec.co.uk in

Auxetec develops patented liquid crystal elastomers with auxetic properties that resist impact, aimed at improving the durability and longevity of products in demanding applications.

Advanced ManufacturingDeep TechNew Materials

BOWusebow.com in

OLO Robotics builds products designed to simplify robotics development, aiming to make robotics accessible to users regardless of their level of expertise.

Developer ToolsEnterprise SoftwareRoboticsSaaSSheffield, GB

Co-investorsSyndicateRoom

Cytotrait Managed by: Hassan Mahmudulcytotrait.com in

Cytotrait develops genetic technologies for crop improvement through chloroplast engineering.

AgTechBiotechManchester, GB

Junwei Ji(Co-Founder & Executive Director)inAnil Day(Co-founder & Scientific Advisor)Tim Brears(Executive Chair)in

Co-investorsUK Innovation & Science Seed Fund

Exciting Instrumentsexcitinginstruments.com in 𝕏Nov 2024

Exciting Instruments builds the EI-FLEX benchtop platform, a single-molecule fluorescence instrument combining smFRET, FCS and FCCS to measure biomolecular interactions and dynamics directly in solution.

BiotechDeep TechHardware

Timothy Craggs(Founder and CEO)

Co-investorsCambridge Innovation Capital Empirical Ventures Praetura Ventures

Floreonfloreon.com inNov 2023

Floreon develops a patented bioplastic material designed to reduce carbon footprint and replace traditional oil-based plastics in manufacturing processes.

Circular EconomyCleantechNew MaterialsSheffield, GB

Shaun Chatterton(Founder and Chairman)in

Iceotopeiceotope.com in

Iceotope develops precision liquid cooling technology for data centers, AI infrastructure, and edge computing systems.

AI & Machine LearningCleantechDeep TechHardwareSheffield, GB

Co-investorsAster Capital Ombu Group Salica Investments

Literal Labsliteral-labs.ai in 𝕏Jun 2025

Literal Labs develops logic-driven AI technology, positioning its work as an alternative approach to machine learning.

AI & Machine LearningDeep TechIoT

Noel Hurley in Leon Fedden inProfessor Alex YakovlevProfessor Rishad Shafik

Co-investorsGMG Ventures Mercuri.vc Sure Valley Ventures

Microlubmicrolub.com inOct 2024

MicroLub is a UK-based deep-tech ingredient company that develops protein-based biolubricant molecules — protein microgels coated with polysaccharides — that reduce molecular friction to replace fats and oils in food and personal care products while retaining their mouthfeel and texture.

BiotechDeep TechFoodTechLeeds, GB

Anwesha Sarkar(Founder)in

Co-investorsLIFTT Praetura Ventures

MicroLubmicrolub.co.uk in

MicroLub is a deep-tech ingredient company that develops protein-based biolubricant molecules which reduce molecular friction to replace fats and oils in food and personal care products while retaining fat-like mouthfeel and texture.

Deep TechFoodTechNew MaterialsLeeds, GB

Mimetrikmimetrik.tech inAug 2023

Mimetrik is a dental technology spinout from the University of Leeds founded by practicing dentists, developing digital solutions for the clinical dental pathway.

Deep TechHardwareHealthtechMedical DevicesLeeds, GB

Optalysysoptalysys.com in 𝕏Jan 2026

Optalysys is a photonic computing company using silicon photonics to turn the optical layer into an arithmetic engine for high-performance computing.

Deep TechHardwareSemiconductorsLeeds, GB

Co-investorsAnglia Capital Group imec.xpand Verve Ventures

Opteranopteran.com

Opteran develops autonomy software for robots and machines by reverse-engineering neural algorithms from insect brains, using computational neuroscience rather than deep learning.

AI & Machine LearningDeep TechRoboticsLondon, GB

James Marshall(Founder & Science Officer)Alex Cope(Co-founder & CTO)inDavid Rajan(CEO & Co-founder)

Co-investorsEpisode1 IQ Capital

Partfulpartful.io in 𝕏Dec 2024

Partful builds a 3D interactive parts catalog platform that gives equipment operators and aftermarket end-users a real-time, immersive view of parts and repair instructions connected to the manufacturer.

Advanced ManufacturingEnterprise SoftwareLogistics & Supply ChainSaaS

Co-investorsBlumberg Capital

Penciltrypencil.com in 𝕏Sep 2023Acquired

Pencil is an AI operating system for marketing that aggregates multiple AI models (from OpenAI, Google, Adobe, Runway, and Bria) into one orchestration layer with enterprise governance controls.

AI & Machine LearningEnterprise SoftwareMarketing TechSingapore, SG

Will Hanschell(CEO)in Sumukh Avadhani(CTO)in

Co-investorsEntrepreneur First Wavemaker Partners Artesian Catapult Ventures Martlet Capital Mumbai Angels +5 more

Pencil Biosciences - companypencilbiosciences.com in

Pencil Biosciences develops a fully synthetic, modular, non-CRISPR gene editing platform that edits DNA without causing a break or nick.

BiotechDeep TechHealthtech

Co-investorsEMV Capital Future Planet Capital Martlet Capital Octopus Ventures UK Innovation & Science Seed Fund

Phagenesisphagenesis.com in 𝕏Mar 2024

Phagenesis develops targeted pharyngeal electrical stimulation technology to treat neurogenic dysphagia by restoring neural pathways for safe swallowing.

Deep TechDigital HealthHealthtechMedical Devices

Co-investorsAphelion Capital Innvotec Ltd.EQT Life Sciences Sectoral Asset Management

Phluxphluxtechnology.com in

Phlux Technology develops Noiseless InGaAs avalanche photodiode (APD) infrared sensors operating at 1550 nm that serve as drop-in replacements for traditional APDs.

Deep TechHardwareSemiconductors

Ben White(CEO)in

Co-investorsOctopus Ventures

Phovirphovir.com in

PhovIR develops handheld near-infrared (NIR) spectroscopy technology based on a MEMS-enabled Michelson interferometer, packaging FTIR-grade material analysis into a small, low-cost, mass-manufacturable device.

Deep TechHardwareNew MaterialsManchester, GB

Tim Echtermeyer(Founder)in

Pixelpixel.xyzJul 2026

A crypto platform gamifying the casino experience with blockchain technology.

Co-investorsHack VC HTGF SCVC LP

Plasma Freshplasma-fresh.comJul 2025

Conveyor belt technology to reduce cross-contamination risks in the food industry.

Co-investorsDeepbridge Capital

PragmatIC Semiconductorpragmaticsemi.com in 𝕏

Pragmatic is a European semiconductor company developing clean chips designed to reduce carbon emissions and waste compared to silicon alternatives.

CleantechDeep TechHardwareSemiconductorsCambridge, GB

Scott White in Richard Price in

Co-investorsCambridge Innovation Capital In-Q-Tel Prosperity7 Ventures ARM British Patient Capital Catalyst +4 more

Qvbio.Coqvbio.co.uk in 𝕏

QV Bioelectronics develops GRACE, an implantable electric field delivery platform designed to treat aggressive cancers by delivering continuous therapeutic electric fields directly to tumor sites.

BiotechDeep TechHealthtechMedical Devices

Dr Chris Bullock(CTO & Co-Founder)Dr Richard Fu(Clinical Director & Co-Founder)

Recourse Airecourseai.com in

Re:course develops natural language processing technology to enable machines to understand and communicate with humans in healthcare settings.

AI & Machine LearningDigital HealthEdTechEnterprise SoftwareHealthtechSaaS

Co-investorsOnstage

Silveray Seedsilveray.co.uk in

Silveray develops flexible X-ray detectors using patented semiconductor ink technology for non-destructive testing in industrial applications including oil and gas, nuclear energy, aerospace, and shipbuilding.

Advanced ManufacturingDeep TechHardwareStockport, GB

Co-investorsCambridge Angels group Future Planet Capital UK Innovation & Science Seed Fund ACF Investors

Simanalyticasimanalytica.com in

Locus is a place-based analysis platform that integrates climate risk assessment, regional decarbonization planning, energy network analysis, and spatial planning tools for local authorities, utilities, and developers.

AI & Machine LearningCleantechClimate TechData & InfrastructureEnergyEnterprise SoftwareGovTechPropTech

Rob(CEO)

Sitehopsitehop.comOct 2025

Sitehop provides encryption technology designed for real-time data protection that prioritizes speed and quantum-readiness.

CybersecurityDeep TechEnterprise SoftwareHardwareQuantum Computing

Melissa Chambers(Co-Founder and CEO)inBen Harper(Co-Founder and CTO)in

Co-investorsAmadeus Capital Partners Manta Ray Ventures Osney Capital Mercia Ventures

Uominnovationfactoryuominnovationfactory.com in 𝕏

The University of Manchester's technology transfer office that commercializes academic research and intellectual property through spinout creation and licensing arrangements.

Deep TechEnterprise SoftwareImpact & Social GoodManchester, GB

Other

Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.

Apini TherapeuticsImperagenMimetrik.CoOLO RoboticsQV Bioelectronics

Portfolio news

latest coverage across their companies

MicroLub raises $10m to scale protein-based technology for lower-fat, higher-protein foods - Microlub

MicroLub · microlub.com · Sep 24, 2026

Optalysys secures £23m to advance photonic computing and US expansion

Optalysys · optalysys.com · Jan 22, 2026

Sitehop Raises £7.5m to Future-Proof Networks Against Quantum Threats | Sitehop

Sitehop · sitehop.com · Oct 9, 2025

PhovIR secures £4 million to bring breakthrough optical sensor technology to market - Phovir Technologies Ltd

Phovir · phovir.com · Aug 27, 2025

Principals & officers · per Companies House

what is this? ⓘ

Claire Helen Blackburn

Secretary · since 2023

Andrew Mcculloch Graham

Director · British · since 2020

James Marshall Hadley

Director · British · since 2022

Susan Elaine Hartley

Director · British · since 2022

Anthony John Professor Holden

Director · British · since 2026

Duncan Edward Johnson

Director · British · since 2021

Alexander Ian Macpherson

Director · British · since 2021

Jane Elisabeth Madeley

Director · British · since 2021

Terence James O'neill

Director · British · since 2021

Niranjan Srihari Sirdeshpande

Director · British · since 2022

Fund performance · per public LP disclosures

as of Sep 2025

Fund	Vintage	Committed	Net IRR	TVPI	DPI
Northern Gritstone LimitedLPs: West Yorkshire Pension Fund	—	—	—	0.95x	0.00x

Source: public limited-partner disclosures (CalPERS, CalSTRS). Net IRR / TVPI / DPI as reported by the limited partner; a fund's early-year IRR is an interim estimate (J-curve).

Frequently asked questions

How many investments has Northern Gritstone made?: Northern Gritstone has 37 tracked investments, 1 of which have exited, including 9 dated in the last 24 months.
What stage does Northern Gritstone invest at?: Northern Gritstone invests at the Pre-Seed, Seed, Series A, Series B, Series C, Growth stages.
What sectors does Northern Gritstone focus on?: Northern Gritstone focuses on AI & Machine Learning, Biotech, Cleantech, Deep Tech, Energy, Hardware, Healthtech, Impact & Social Good, Longevity, Medical Devices, New Materials, SaaS, Semiconductors.
Where is Northern Gritstone located?: Northern Gritstone is headquartered in Manchester, GB.
Does Northern Gritstone lead rounds?: Northern Gritstone typically participates in rounds rather than leading them.
Who does Northern Gritstone co-invest with?: Northern Gritstone most often shares deals with Future Planet Capital, IQ Capital, Octopus Ventures, among 28 tracked co-investors.

Images

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