Cowtown Angels — Full Portfolio

CorInnova develops a minimally invasive, non-blood contacting cardiac assist device designed to treat acute heart failure patients who cannot use existing solutions.

Deep TechHealthtechMedical DevicesHouston, US

JCJohn Criscione(Director)inWAWilliam Altman(Executive Officer, Director)inDennis Robins(Director)Boris Leschinsky(Executive Officer)Clarice Motter(Executive Officer)Keith Svagerko(Executive Officer)

Co-investorsHOHouston Angel NetworkKEKeiretsu ForumTMTMC Venture FundHAHarvard Business School Alumni Angels of Greater New YorkWEWellcome TrustAGAggie Angel Network+2 more

Altis Biosystems builds RepliGut®, human intestinal tissue models grown from human intestinal stem cells that provide human-relevant preclinical data for drug absorption, metabolism, toxicity, and disease modeling.

BiotechDeep TechHealthtechMedical DevicesDurham, US

Christopher Sims(Executive Officer)inJimmy Smedley(Executive Officer)inSamuel Franklin(Director)Joseph McMahon(Director)Michael Biron(Executive Officer, Director)

BoardChristopher Perkins(Director)

Co-investorsATAtlanta Technology AngelsCECentral Texas Angel NetworkCHCheckmate Capital Group LLCHAHatteras Venture PartnersJOJohnson Venture PartnersNCNC IDEA+1 more

Arovia manufactures Splay, a portable display device that combines a collapsible screen with ultra-short-throw projection technology for productivity, presentations, and entertainment.

ConsumerDeep TechHardwareNew MaterialsHouston, US

AAlex(Co-founder, Optical Engineer)ADAlexander David Wesley(Executive Officer, Director)inGSGeorge Shengliang Zhu(Founder)inAWAlexander Wesley(Founder)inTaylor Yoke(Executive Officer, Director)Rahul Chandra(Executive Officer)

Co-investorsBOBoot64 VenturesGAGaingelsGOGOOSE CapitalHOHouston Angel NetworkTETexas HALO Fund

Ateios develops electrode manufacturing techniques designed to accelerate production speed, reduce carbon emissions, and decrease the physical footprint of battery manufacturing and gigafactories.

Advanced ManufacturingCleantechEnergyMedical DevicesNew MaterialsLa Jolla, US

Terry Taber(CTO)

Co-investorsCACarat Venture PartnersCHCharmides CapitalE8E8 AngelsELElevate VenturesGOGood Growth CapitalHGHG Ventures+7 more

Atticus Pharma develops immunodermatology therapeutics using patented sustained-release technology for enhanced delivery to the viable epidermis.

BiotechHealthtechMedical Devices

Co-investorsAEAEON FoundryVEVentureSouth

Austlen makes the Entourage, a convertible stroller that transforms between single, double, and sit-and-stand configurations for growing families.

ConsumerHardware

BMI OrganBank develops organ perfusion and preservation systems to improve transplantation outcomes and extend organ viability outside the body.

AI & Machine LearningBiotechDeep TechHealthtechMedical DevicesWinston-Salem, US

George Barr(Founder)inCDCarrie DiMarzio(CEO)in

Co-investorsBABand of AngelsNENew York Angels

CAGE Bio is a clinical-stage biotech developing localized topical treatments for dermatology, inflammation, and immunology conditions using its proprietary deep eutectic ionic liquid platform.

BiotechDeep TechDigital HealthSan Carlos, US

Nitin Joshi(Executive Officer, Director)Samir Mitragotri(Director)Ravi Srinivasan(Executive Officer, Director)

BoardJeff Keyser(Director)

Chromis Technologies engineers and manufactures custom amorphous fluoropolymers, marketed under the CyclAFlor brand, with tunable optical, chemical, and electrical properties for applications such as semiconductor pellicles, optical coatings, gas separation membranes, and fuel cell ionomers.

Advanced ManufacturingDeep TechNew MaterialsSemiconductorsWarren, US

Whitney White(Chief Technology Officer)inFJFrank J. Graziano(Chief Executive Officer)inMiri Park(Chief Operating Officer)in

BoardPeggy Wallace(Director)Boying Barry Zhang(Director)Bill Michaels(Director)

Co-investorsBOBoston Harbor AngelsNENew York Angels

Cognition Therapeutics is a clinical-stage biotechnology company developing zervimesine (CT1812), an investigational once-daily oral small-molecule therapy designed to protect brain synapses by blocking toxic protein oligomers.

BiotechHealthtechPittsburgh, US

SCSusan Catalano(Executive Officer, Director)inSusan Catalano, Ph.D.(Co-founder)LRLisa Ricciardi(Chief Executive Officer)inHarold Safferstein(Executive Officer, Director)

BoardNada Jain(Director)Franz Hefti(Director)

Co-investors3E3E Bioventures CapitalARArieal Southeast Angel PartnersATAtlanta Technology AngelsBIBios PartnersDODolby Family VenturesGOGolden Seeds+2 more

Cx Precision Medicine develops blood-based diagnostic tests for Alzheimer's and other neurodegenerative diseases, delivering precision medicine tools for early diagnosis and personalized treatment in primary care settings.

AI & Machine LearningBiotechDigital HealthMedical DevicesFort Worth, US

Sid O'Bryant(Scientific Founder, Executive Director of the Institute for Translational Research)FGFrank Gerome(Director, CEO and President)in

Eisana Health is an early-stage medical device company developing a patient-centered cooling system — including cooling gloves, booties, and a portable chiller — to prevent chemotherapy-induced peripheral neuropathy (CIPN) in cancer patients.

HardwareHealthtechMedical Devices

Carole Spangler Vaughn(Founder)

Encore Vision supplies eyewear frames and operates a full-service digital optical lab, offering combined frame-and-lens solutions to eyecare practices.

HealthtechRetail TechFort Worth, US

Evelyn Blake(Executive Officer)William R. Burns(Executive Officer, Director)in

BoardLes Kreis(Director)Robert Willard(Director)John Hunkeler(Director)Adrienne Graves(Director)

Co-investorsBIBios Partners

Evecxia Therapeutics develops 5-HTP-based drugs using proprietary drug delivery technologies designed to increase brain serotonin production as adjunctive treatments for depression and other mental disorders.

BiotechDigital HealthMental HealthResearch Triangle Park, US

MCMarc Caron(Executive Officer, Director)MCMarc Caron, PhD(Founder)Jacob Jacobsen, PhD(Co-Founder & Chief Executive Officer)JJJacob Jacobsen(Executive Officer, Director)inDavid Zaccardelli(Director)Roger Jeffs(Director)

Co-investorsEVEvolution VC PartnersAVAvAir Investments

Green Steel Environmental develops PSR™, a non-hazardous alternative to chemical treatments for removing phosphorus and sulfur from wastewater at treatment facilities.

Advanced ManufacturingCircular EconomyCleantechImpact & Social GoodNew MaterialsBoulder, US

Co-investorsCECentral Texas Angel NetworkRORockies Venture ClubSYSymbiotic Ventures

Digi International is a technology company that builds and manages connectivity hardware and IoT infrastructure for enterprises requiring secure, always-on systems.

Enterprise SoftwareHardwareIoT

Interplay Learning builds online skilled trades courses designed and delivered by industry experts and instructional designers, covering foundational technical knowledge and real-world applications for technicians.

EdTechEnterprise SoftwareFuture of WorkHR TechSaaSAustin, US

Douglas Donovan(Executive Officer, Director)

BoardICIan Chiu(Director)inCPCharlie Plauche(Director)inRichard Waitumbi(Director)Sam Decker(Director)Kimberly Caldbeck(Director)

Co-investorsCACathexis VenturesCECentral Texas Angel NetworkCECerity Partners VenturesGUgumi IncMAMasco VenturesOWOwl Ventures+8 more

Little Passports is a direct-to-consumer children's subscription brand that ships monthly activity kits with hands-on projects, stories, stickers, and activity books focused on geography, culture, science, and art.

ConsumerDirect to ConsumerEdTechSan Francisco, US

ANAmy Norman(Executive Officer, Director)inStella Ma(Executive Officer, Director)

BoardAldo Manzini(Director)inTyler Head(Director)JDJennifer Dulski(Director)inSheri Anderson(Director)

Co-investorsASAstiaGOGolden SeedsNENext Play Ventures

MOGL operates a marketplace and software platform for NIL (name, image, and likeness) deals in collegiate athletics, connecting student-athletes with donors and brands.

Marketing TechMarketplacesSaaSSports Tech

MHMatthew Himelstein(Chief Product & Technology Officer)inASAyden Syal(Co-founder & Chief Executive Officer)inBWBrandon Wimbush(Co-founder & Advisor)in

Co-investorsAPAperture Venture CapitalEVEvolution VC PartnersIRIrishAngelsLILitquidity VenturesSASand Hill AngelsCHChaos Ventures+3 more

OmniLife Health develops FlowHawk, a clinical workflow automation platform that helps care teams manage complex care pathways, with initial focus on organ transplant centers.

Digital HealthEnterprise SoftwareHealthtechBeaverton, US

Co-investorsBOBoston Harbor AngelsDADakota Venture GroupKEKeyhorse Capital

VistaApex Solutions is a dental healthcare company formed by uniting the VistaApex, PerioProtect, and PerioSciences brands, offering products such as antioxidant-based oral care, FDA-cleared non-invasive tray therapy for gum disease, and clinical endodontic and operatory materials.

ConsumerDirect to ConsumerHealthtechMedical DevicesWellness & Fitness

RMRussell Moon(Founder)in

Co-investorsGRGreen Park & Golf Ventures

Prosoria is an over-the-counter consumer healthcare company that develops pharmaceutical-grade products for chronic health conditions using scientifically-tested formulations.

ConsumerDirect to ConsumerHealthtechWellness & Fitness

Co-investorsHOHouston Angel NetworkNONorth Texas Angel Network

Seattle, US

RVRyan Vogel(CEO)in

Co-investorsDADakota Venture GroupRORobin Hood VenturesRORockies Venture ClubSWSWAN Impact Network

Renerva develops implantable medical devices to treat peripheral nerve injuries.

BiotechDeep TechHealthtechMedical DevicesPittsburgh, US

LSLorenzo Soletti(LLC Manager)inBryan N. Brown(Chief Technology Officer)inWAWilliam A Sekkel(LLC Manager)inPeter DeComo(LLC Manager)J. Christopher Flaherty(Executive Vice President for Intellectual Property)Paul A Gardner(Chief Medical Officer)

SageMedic is a California-licensed clinical laboratory providing cancer treatment testing and diagnostics through its SAGE Oncotest™ platform.

BiotechHealthtechMedical Devices

CAChris Apfel(Founder, CEO & Chair)inBrigitte Apfel(Co-Founder, Treasurer)

Co-investorsKEKeiretsu Forum

Decoy Therapeutics is a biotechnology company developing Designable Multi-Antivirals (D-MAVs), peptide conjugate antivirals built on its AI-enabled IMP³ACT platform to target viral mechanisms conserved across multiple viruses.

AI & Machine LearningBiotechHealthtech

Co-investorsCECentral Texas Angel NetworkDEDellin Investments

Strategic Thermal Labs develops liquid cooling technology for data centers, including a CDU-replacement solution that eliminates cooling distribution units and recovers power budget.

CleantechDeep TechHardware

Stream Biomedical is a clinical-stage biotechnology company developing LG3, a biologic derived from a natural repair protein intended to protect and restore the brain by activating its repair systems.

BiotechDeep TechHealthtechHouston, US

H. Davis Adkisson(Chief Scientific Officer)inChris Garabedian(Director)William Schwieterman(Board of Directors)Fred Callori(Director)

BoardADAmanda De La Garza(Director)in

Co-investorsBIBios Partners

True Made Foods makes condiments such as ketchup and barbecue sauce that use fruits and vegetables for sweetness instead of added sugar or high fructose corn syrup.

ConsumerDirect to ConsumerFoodTechAlexandria, US

AKAbraham Kamarck(Executive Officer, Director)inAbe Kamarck(Founder)Ed Mitchell(Co-founder, Legendary Pitmaster)Ryan Mitchell(Co-founder, Co-Pitmaster)

BoardRichard Scheiner(Director)

Co-investorsBLBlack Jays VenturesCECentral Texas Angel NetworkSISiddhi CapitalSOSOSV

Tympanogen develops Perf-Fix, a gel patch system for nonsurgical eardrum (tympanic membrane) repair that replaces traditional tympanoplasty with a clinic-based procedure.

BiotechHealthtechMedical DevicesRichmond, US

EHElaine Horn-Ranney(Executive Officer, Director)in

Co-investorsCICitrine AngelsVIVirginia Venture Partners

SelfWrap develops bioabsorbable wrap materials for vascular grafts that conform to individual patient anatomy and are designed to be absorbed by the body, unlike alloy-based alternatives.

BiotechDigital HealthHealthtechMedical DevicesHouston, US

TBTim Boire(Founder)inGLGeoffrey Lucks(Founder)in

BoardJWJoel Whitley(Director)inJim Monsor(Director)RCRobert Crutchfield(Director)in

Co-investorsALAlumni VenturesC3C3 VenturesCRCreative VenturesGOGood Growth CapitalHEHealth WildcattersKUKube VC+9 more

Vessl designs adaptive prosthetic technology that adjusts to the body's dynamic changes to provide consistent comfort and natural movement for amputees.

Advanced ManufacturingHardwareHealthtechMedical DevicesWellness & FitnessIlderton, CA

Co-investorsARArieal Southeast Angel PartnersRORobin Hood VenturesTETechstars

Zylö Therapeutics develops therapeutic delivery technology, focusing on product development in the biotech and drug-delivery space.

BiotechHealthtechGreenville, US

SRScott R. Pancoast(CEO & Founder)inCECharles E. Hinkle(Chief Financial Officer)inADAndrew Draganski(Vice President, Product Development)Thomas Patrick Murray(Executive Officer)Lance Michael White(Director)Gary J Atkinson(Director)

Co-investorsAEAEON FoundryARArieal Southeast Angel PartnersBOBoston Harbor AngelsHBHBS Angels of Boston