ARCH Venture Partners — 2026 Investments

Moleculent develops biological discovery and disease understanding tools for scientists.

AI & Machine LearningBiotechDeep TechSolna, SE

FRFredrik Roos(CTO & Co-founder)in

Co-investorsEIEIR Ventures

Ramona Optics builds parallelized multi-camera array microscope systems for imaging and analyzing small model organisms and cell cultures in multi-well plates.

BiotechDeep TechHardwareDurham, US

RHRoarke Horstmeyer(Director)inMark Harfouche(Executive Officer, Director)inRobert Horstmeyer(Director)Margaret Aery(Executive Officer)inGregor Horstmeyer(Executive Officer, Director)

Board seatSKSean KendallPWPatrick Weiss· per SEC Form D · $31M raise · filed Mar 2026

Co-investorsTHThe E14 Fund

SonoThera is developing a nonviral, non-invasive gene delivery technology that uses ultrasound and microbubbles (ultrasound-mediated delivery) to deliver genetic payloads to targeted sites in a redosable way.

BiotechDeep TechDigital HealthHealthtechSouth San Francisco, US

KGKenneth Greenberg(Co-Founder, President & CEO)in

Board seatSteven Gillis· per SEC Form D

Co-investorsVIVida VenturesLELeaps by BayerFOFoothill VenturesILIllumina VenturesMEMedical Excellence CapitalVIVivo Capital+8 more

Countable Labs (formerly Enumerix) develops Countable PCR, a DNA quantification technology that provides absolute target counts at single-molecule resolution as an alternative to qPCR, digital PCR, and NGS.

BiotechDeep TechHealthtechMedical DevicesPalo Alto, US

SFStephen Fodor(Co-Founder & Board Director)ACAri Chaney(Co-Founder & Board Director)inCFChristina Fan(Co-founder + CTO)inGPGiovanna Prout(Chief Executive Officer)in

Co-investorsF-F-Prime CapitalPRPrimer Ventures

Lightcast develops a single-cell functional analysis platform that uses droplet-based technology to profile cell function, biomolecule secretion, cell-cell interactions, and targeted cell killing at scale.

BiotechDeep TechHealthtech

Co-investors+N+ND CapitalILIllumina VenturesLOLongwall Venture Partners LLPM M VenturesOMOMX Ventures

Lightcast provides a next-generation single-cell functional analysis platform called Envisia that enables massively parallel profiling of cell-cell interactions and biomolecule secretion at scale.

BiotechDeep TechMedical DevicesCambridge, GB

Co-investorsILIllumina VenturesPEPerscitus LLP+N+ND CapitalM M VenturesOMOMX Ventures

Maze is a security company, founded in 2024, that uses AI to help defenders identify and address vulnerabilities in code and cloud environments.

AI & Machine LearningCloud ComputingCybersecurityDeveloper Tools

Adrian Jozwik(Founder)Alexandre Sieira(Founder)Harry Wetherald(Founder)Jonathan Widawski(Founder)Santiago Castineira(Founder)Thomas Mary(Founder)

Co-investorsTATapestry VCTHTheory VenturesAMAmplify PartnersCHCherry VenturesEMEmergence Capital PartnersGEGeneral Catalyst+2 more

Mirador provides digital lending platform software for financial institutions, credit unions, and banks to streamline online loan applications.

Cloud ComputingEnterprise SoftwareFintechSaaS

Co-investorsCOCore Venture CapitalNYNycaNYNyca PartnersFIFidelity InvestmentsINInvusOROrbiMed+3 more

CREATE Medicines develops in vivo CAR immunotherapy using proprietary mRNA-LNP technology to program T cells, NK cells, and myeloid cells directly within the body for cancer, autoimmunity, and fibrosis.

AI & Machine LearningBiotechHealthtechMedical DevicesCambridge, US

DGDaniel Getts, Ph.D.(Chief Executive Officer, Cofounder, Board Director)

Co-investors8V8VCALAlexandriaHAHatteras Venture PartnersNENewpath Partners

Oratomic builds fault-tolerant quantum computers using ultra-efficient error correction with light and atoms.

AI & Machine LearningDeep TechQuantum Computing

Dolev Bluvstein(Founder)inMadelyn CaininManuel Endres(Founder)

BoardJohn Preskill

Co-investorsBABain Capital VenturesGEGeneral CatalystINIndex VenturesKHKhosla VenturesSPSpark CapitalBEBezos Expeditions+3 more

Prometheus Fuels develops systems that convert intermittent renewable energy into liquid fuels for remote electrification.

Advanced ManufacturingCleantechClimate TechDeep TechEnergySanta Cruz, US

RMRob McGinnis(CEO)inDr. Rob McGinnis(Founder)Seonah Jin(Senior Director of Engineering)

Co-investorsBMBMW i VenturesEMEmles Venture PartnersEXExpaMAMaersk GrowthMEMetaplanetY Y Combinator+12 more

Syndex develops mcPCR (methyl copying PCR), a proprietary platform technology that amplifies DNA while preserving methylation patterns, addressing the challenge of low DNA levels in clinical samples.

BiotechDeep TechMedical DevicesSanta Monica, US

GSGeoff Smith(Founder & CEO)inJBJason Betley(Chief Product Officer)in

Co-investorsOMOMX Ventures+N+ND Capital

Transcripta Bio develops medicines for patients with serious diseases by mapping how molecules affect human cells at single-cell resolution.

AI & Machine LearningBiotechDeep Tech

Co-investorsBLBlueYard CapitalJAJAZZ Venture PartnersDCDCVC BioINInsight PartnersMAMayo Clinic Ventures

Trase builds AI systems with built-in governance and auditability for organizations in high-stakes domains such as defense, healthcare, and critical infrastructure.

AI & Machine LearningDeep TechDefense TechEnterprise Software

JLJoe Laws(Co-Founder and Chief Architect)inGVGrant Verstandig(Co-Founder and CEO)in