Mental Health Startups

Mental is a mobile app that helps men improve their mental well-being through action-oriented tools for managing stress, building discipline, and finding purpose. It offers evidence-based programs such as a Cold Shower Protocol and AI-based coaching developed with psychology PhDs.

4 investors

Mentavi Health provides clinician-reviewed online diagnostic evaluations that screen for up to 29 mental health conditions, including ADHD, anxiety, depression, and OCD, with results reviewed by licensed doctorate-level psychologists. It serves patients directly and partners with health systems, primary care providers, higher-education institutions, and employers across the United States.

4 investors

Mindoula is a population health management company that identifies, engages, and supports people with complex behavioral health, medical, and social needs using a technology suite of data science, psychometrics, predictive analytics, and AI combined with virtual and in-person care teams. It serves health plans, health systems, hospitals, and provider groups to extend their reach toward value-based care.

4 investors

Mindset is a daily wellness and self-care app featuring audio collections and stories from celebrities and experts. The platform serves individuals seeking mental health support and community connection through curated content, daily check-ins, and peer-sharing features.

4 investors

MoneyStack provides financial counseling services to mental health and behavioral health professionals for their clients experiencing acute financial distress. The company helps individuals and families develop financial recovery plans and rebuild their relationship with money as part of their overall recovery from behavioral health challenges.

4 investors

Myndlift offers a neurotherapy platform that combines neuroscience with consumer technology to help people improve their brain health and cognitive well-being. The company serves tens of thousands of users seeking to optimize cognitive performance.

4 investors

Naluri develops digital therapeutics that combine behavioral science and coaching to help individuals reduce chronic disease risk, improve mental resilience, and build lasting healthy habits. The company serves employers across Southeast Asia.

4 investors

Nema Health provides trauma-focused mental health treatment for patients with PTSD and C-PTSD, using Cognitive Processing Therapy (CPT) delivered by licensed therapists. The company serves patients seeking evidence-based trauma care with virtual access and insurance coordination.

4 investors

Neurovalens develops medical devices using neuromodulation technology to address health conditions including obesity and anxiety disorders. The company conducts research and development activities supported by European funding programs.

4 investors

Nivati is an employee mental health and wellbeing platform that combines an AI-powered companion app with access to licensed therapists, dietitians, financial coaches, group workshops, self-guided content, and 24/7 call and chat therapy. It is sold to employers as a replacement for traditional EAP services, with analytics and ROI tools for HR teams.

4 investors

Opya provides early intervention ABA (applied behavior analysis) therapy for young children diagnosed with autism and their families. It operates as an accredited autism care provider in California.

4 investors

Poppy Seed Health offers an app that connects pregnant and postpartum people, and those experiencing pregnancy loss, to a network of doulas, midwives, and nurses via on-demand text chat. It provides emotional and mental health support through a membership or pay-per-chat model, with access to a library of evidence-based resources.

4 investors

Psilera is a biotech company developing neuroscience-focused therapeutics, including its lead asset PSIL-006, described as next-generation mindful medicine.

4 investors

PursueCare provides addiction treatment and mental health services designed to increase accessibility to comprehensive care. The company operates an in-house pharmacy, PursueCareRx, offering addiction, psychiatric, and maintenance medications with delivery services.

4 investors

RethinkFirst provides behavioral health software and evidence-based tools, including autism (ASD) treatment training and special needs/behavior management solutions, serving K-12 education, employers, providers, and payors. Founded in 2007, the company applies data science and analytics to support value-based care for individuals with behavioral health challenges and their caregivers.

4 investors

Reunion Neuroscience is a clinical-stage biopharmaceutical company developing serotonergic psychedelic therapies for mental health conditions such as postpartum depression, adjustment disorder, and generalized anxiety disorder. Its lead candidate, luvesilocin (RE104), is a short-duration prodrug of 4-OH-DiPT that targets the serotonin 2A receptor.

4 investors

Sharp Performance provides performance coaching and stress management training for professionals in high-stress roles, drawing on expertise from military special operations and sports psychology backgrounds.

4 investors

Shimmer provides coaching, community, and digital tools designed specifically for people with ADHD, combining expert guidance with peer support to help them reach their potential. The platform serves neurodivergent individuals seeking ADHD-specific support outside traditional mental health systems.

4 investors

SilverCloud by Amwell is a digital mental healthcare platform designed to provide mental health services to a broad audience. The company is committed to accessibility standards for disabled users.

4 investors

Sonder is an app-based wellbeing service combining mental health, medical and safety support with 24/7 human care from specialists and clinicians, positioned as a replacement for traditional Employee Assistance Programs. It serves employers and their workforces, offering real-time alerts, de-identified risk reporting on psychosocial hazards, and early-intervention support, with a focus on the Australian market.

4 investors

Storybook is a mobile app that helps parents establish bedtime routines through stories and massage techniques intended to improve children's sleep and strengthen parent-child bonding. It is aimed at families and marketed toward parents of young children.

4 investors

Synendos is a biotech company developing selective endocannabinoid reuptake inhibitors targeting the endocannabinoid system to treat neuropsychiatric disorders. The company's lead candidate, SYT-510, is in clinical development with the goal of restoring brain function in major psychiatric and neurological conditions.

4 investors

TandemStride is an app-based platform that connects physical trauma survivors and their loved ones with trained peer mentors, guided resources, and a supportive recovery community. It also works with trauma centers, community-based organizations, and health plans through a national trauma peer network.

4 investors

TAO Connect provides an online library of over 150 interactive mental health sessions, courses, and practice tools spanning self-guided development, skill building, and clinician-delivered treatment using evidence-based approaches like CBT and ACT. It serves organizations such as employers, educational institutions, and treatment providers, offering progress measures (PHQ-9, GAD-7, WHO-5), reporting dashboards, and partner support.

4 investors