Digital Health Startups

Gilgamesh Pharmaceutical develops novel chemical entities for psychiatric disorders using medicinal chemistry and AI-powered translational platforms to design rapid-acting therapies targeting neurobiological mechanisms rather than symptom management. The company's pipeline spans depression, anxiety, addiction, and schizophrenia, with programs validated by AbbVie's acquisition of its first asset and partnerships with Columbia University and the National Institute on Drug Abuse.

17 investors

Piction Health provides online dermatology care, letting patients submit information about a skin, hair, or nail concern and receive a personalized care plan reviewed by a dermatologist within 24-48 hours. It offers ongoing support through online check-ins for patients seeking remote dermatological care.

17 investors

Color Health operates a nationwide virtual cancer clinic delivering oncologist-led care, screening, and treatment management for employer, union, health plan, and public sector populations. The company combines genetic testing, clinical assessment, diagnostic acceleration, and survivorship support to improve cancer outcomes and reduce costs.

16 investors

One Health operates a clinical trial platform using canine cancer data to accelerate and de-risk human oncology drug development. The company leverages a dataset of 2 billion datapoints from dogs with naturally occurring cancer to serve as a comparative model for pharmaceutical R&D, helping drug developers validate efficacy and identify biomarkers before human trials.

16 investors

GRAIL develops the Galleri blood test for multi-cancer early detection using next-generation sequencing and machine learning to screen for multiple deadly cancer types before symptoms appear. The test is offered by prescription in the United States and through partnerships with healthcare systems, insurance carriers, and diagnostic platforms.

16 investors

Guardant Health develops blood-based testing (liquid biopsy) for cancer detection and monitoring across all stages of the disease. The company serves oncologists, patients, and biopharmaceutical firms with FDA-approved tests for cancer screening, early-stage risk assessment, and treatment selection.

16 investors

Hinge Health builds a digital healthcare platform designed to help individuals manage musculoskeletal health and related conditions. The company serves health plans, employers, and individuals seeking alternative healthcare approaches.

16 investors

Insilico Medicine uses artificial intelligence to discover and develop new drugs, operating an AI-driven platform for pharmaceutical research and development. It collaborates with global biopharma companies and academic institutions on drug discovery projects.

16 investors

Legacy is a men's fertility and reproductive health company that provides sperm testing, analysis, and banking services. It draws on a medical and scientific advisory board of urologists, reproductive endocrinologists, and andrology researchers.

16 investors

Alto Neuroscience is a clinical-stage biopharmaceutical company developing biology-driven medicines for neuropsychiatric conditions, using measurements of brain biology to predict clinical response and identify patients likely to benefit from its drug candidates. Its initial focus areas include major depressive disorder, bipolar depression, and schizophrenia.

15 investors

Cityblock provides primary care and health services focused on making healthcare accessible as a basic right, particularly serving underserved and marginalized communities with an emphasis on trust-based, inclusive care.

15 investors

Docplanner operates a healthcare platform connecting patients with doctors and providing software for medical practices to manage appointments, online presence, and reputation. It serves doctors and patients across 13 countries in Europe and Latin America.

15 investors

Paperspace provided cloud GPU infrastructure and a machine learning development platform, Gradient, for training and deploying AI models. It was acquired by DigitalOcean in 2023.

15 investors

Seven Starling provides virtual mental healthcare and psychiatric support for women experiencing anxiety, depression, or trauma related to fertility, pregnancy, pregnancy loss, postpartum, early parenthood, and menopause. The service matches patients with therapists and psychiatric nurse practitioners, accepts most commercial insurance and Medicaid, and operates across 20+ U.S. states.

15 investors

Thrive Global provides a Microsoft Teams integration that embeds wellbeing tools, stress-reduction features, and science-backed habit-building microsteps directly into employee workflows.

15 investors

Unite Us provides software and data infrastructure for coordinating whole-person care, helping organizations identify social and health needs, deliver services, and track outcomes. It serves healthcare systems, government agencies, managed care and Medicaid plans, and community-based organizations across the United States.

15 investors

Accolade provides virtual healthcare services including primary care, mental health therapy, and benefits navigation for employees and their families. The platform connects members with doctors, therapists, and care advocates to simplify healthcare access and decision-making.

14 investors

Akido Labs develops an AI operating system designed for healthcare that leverages machine learning to enable personalized medical diagnostics and care coordination at scale. The platform aims to make high-quality healthcare accessible regardless of financial means or geography.

14 investors

Ambience is an AI platform that captures clinical encounters in real time, generates documentation, and suggests coding for healthcare providers across 200+ specialties. The platform helps health systems reduce clinician documentation burden, improve revenue integrity through coding accuracy, and ensure compliance.

14 investors

Biolinq develops glucose-sensing technology based on micro-array biosensors for metabolic health monitoring, including continuous glucose monitoring. The company works in the medical device and diagnostics space, with a team drawn from continuous glucose monitoring and diabetes device backgrounds.

14 investors

Forta is a healthcare company focused on helping families achieve better health outcomes with greater convenience. It operates an ethics board that collects, investigates, and resolves concerns raised through a hotline or confidential email.

14 investors

Galileo operates a medical practice combining a technology platform with in-house primary and multi-specialty clinicians to provide accessible, lower-cost care. It serves healthcare consumers seeking treatment for a range of conditions through a new care delivery model.

14 investors

Kindbody is a fertility care provider offering services such as egg freezing, IVF, IUI, and prenatal and gynecological care through its own clinics across the US. It also sells a fertility employee-benefit solution to employers, providing care directly along with insurance and financing options.

14 investors

Noom offers psychology-based weight-loss programs that combine behavior-change lessons, human and AI coaching, and access to prescription GLP-1 medications through its telehealth platform. It serves individuals seeking weight loss and also provides enterprise programs for employers, health plans, and partners.

14 investors