Deep Tech Startups

CatenaBio develops precision conjugation technology using native amino acids to enable biotherapeutic fusions of small molecules, nucleic acids, enzymes, and cells. The company partners with pharmaceutical firms to advance development of novel therapeutic modalities.

11 investors

Citrine provides an AI platform for product development used across organizations, with expertise in materials discovery and advanced manufacturing optimization.

11 investors

Eliyan develops chiplet interconnect PHY technologies, including its NuLink and NuLink-X products, aimed at increasing bandwidth, power efficiency, and lowering total cost of ownership for generative AI and high-performance computing data center systems. The company targets semiconductor and AI infrastructure applications such as chiplet-based designs and HBM memory scaling.

11 investors

Fauna Bio applies AI and computational analysis to its proprietary biobank of data from extreme mammals such as hibernating species to identify drug targets that are conserved across species including humans. The biotech company focuses on discovering novel therapeutics for human diseases based on evolutionary and genomic insights.

11 investors

Finwave Semiconductor is a fabless semiconductor company that designs GaN-on-Silicon (Gallium Nitride) RF products using transistor designs and process technology originating from MIT research. Its chips target RF communications markets including aerospace and defense, mobile infrastructure, smartphones, medical devices, and cloud computing.

11 investors

Foundational Alloy develops engineering alloys through a solid-state process called MetalsFIRST, in which metal is produced without melting to create microstructures unreachable by conventional metallurgy while controlling oxygen and contaminants. It delivers alloys as finished parts, near-net-shape components, and semi-finished stock.

11 investors

Goodfire is an AI interpretability research lab that develops methods to reverse-engineer, debug, and control neural networks' internal representations. Its work spans applications in genomics, materials discovery, robotics, and medical imaging, aimed at teams training and deploying AI models.

11 investors

Hadean is a deep-tech company that builds distributed computing technology. The company positions itself as a scale-up that grew from an early-stage deep-tech startup.

11 investors

Iambic develops AI technologies for drug discovery, using a high-throughput experimental platform to design small-molecule medicines and advance a pipeline of clinical candidates for cancers such as HER2-driven, breast, and ovarian tumors. It serves the pharmaceutical industry through both its own drug pipeline and partnerships.

11 investors

Kanvas Bio operates a platform for discovering, developing, and manufacturing live biotherapeutics based on the human gut microbiome. It combines high-resolution host-microbiome mapping with large-scale anaerobic co-culture manufacturing to support drug development for pharmaceutical and biotechnology partners.

11 investors

Koniku develops co-processors built from biological neurons, using DNA sequences to create receptors that enable sensing applications. Its uses include detecting threats for airport security, drones for identifying buried IEDs, and taste-sensitive devices for quality assurance.

11 investors

Kymera is a clinical-stage biotechnology company developing novel medicines using targeted protein degradation technology to treat diseases caused by previously "undrugged" proteins. The company focuses on advancing small molecule therapies designed to address critical health problems across multiple disease areas.

11 investors

Kyoto Fusioneering develops fusion energy technology and related engineering solutions to enable carbon-neutral power generation and advanced chemical processes such as hydrogen production and carbon capture. The company conducts research in partnership with Kyoto University and other institutions to commercialize fusion energy applications.

11 investors

Moderna develops mRNA-based medicines for infectious and serious diseases using its proprietary mRNA platform and design technology.

11 investors

Momentus builds and operates in-space transport and service vehicles using water plasma propulsion technology, offering foundational infrastructure services for satellite companies, government agencies, and research organizations. It operates in the space infrastructure industry.

11 investors

Mytos builds robotic systems that automate the manufacturing of human cells, converting input stem cells into specific cell types such as neurons and heart cells over multiple weeks. It serves developers of regenerative medicines and cell therapies, aiming to scale production that is otherwise done by hand.

11 investors

NATIX operates a decentralized, crowdsourced camera network that collects multi-camera driving and street-level data globally. The company builds computer vision models and data infrastructure to support autonomous driving development and physical AI applications across industries.

11 investors

North Vector Dynamics is a Canadian defence technology company developing precision interception, autonomy, and advanced propulsion systems, including counter-UAS solutions and hypersonics. It aims to build a full-spectrum sovereign missile capability for Canada and its allies, partnering with defence primes and systems integrators.

11 investors

NOX operates AI-powered metal manufacturing facilities that provide cut-to-spec metal products to American manufacturers with quote and delivery times measured in milliseconds rather than days. The company uses machine learning for inventory optimization, job scheduling, and bin-packing to reduce lead times and scrap in metal supply.

11 investors

Nu Quantum develops quantum networking solutions to enable commercial quantum computer scaling. The company was founded as a spin-out of the University of Cambridge and builds technology for quantum computing utility.

11 investors

Octant is a therapeutics company that develops small molecule drugs to treat protein misfolding diseases. Using synthetic biology, high-throughput chemistry, and AI/ML, the company's Navigator platform studies how target proteins interact within living human cells to enable drug discovery for rare diseases and oncology.

11 investors

Oklo develops advanced fission power plants to deliver emission-free, reliable, and affordable energy, and is also building advanced fuel recycling technologies in collaboration with the U.S. Department of Energy and national laboratories. The company operates in the nuclear energy sector in the United States.

11 investors

Olix develops a novel compute architecture integrating SRAM with photonics to enable more efficient AI model deployment, addressing throughput, cost, and latency limitations of current GPU memory systems.

11 investors

Openwater develops an imaging platform using two optical modalities designed to diagnose and monitor diseases at the size and cost of a smartphone. The platform combines hardware, software, and open-source designs for use in clinical settings at hospitals, research institutions, and government programs worldwide, with trials spanning cancer, neurological disease, mental health, and metabolic conditions.

11 investors