Deep Tech Startups

Lux Aeterna designs and builds reusable satellites to enable defense, intelligence, commercial, and in-space manufacturing customers to conduct space operations more efficiently. The company is developing a fleet of reusable spacecraft as the foundation for a circular space economy.

12 investors

Overview.ai builds custom hardware, edge AI, and software systems that give manufacturers real-time visibility into their production processes to catch defects earlier and reduce waste. It serves industrial manufacturers seeking to improve quality control at scale.

12 investors

Pacific Fusion is developing a high-gain pulsed magnetic inertial fusion system designed to achieve net facility gain, using a modular fast electric pulser, a meter-scale fusion chamber, and small fuel containers. The company aims to produce affordable, on-demand fusion power to meet global energy demand and address climate change.

12 investors

Phaidra develops an AI control platform that uses reinforcement learning to optimize energy efficiency and operational performance in data centers and AI factories. The platform enables autonomous, self-learning systems to manage complex interconnected infrastructure like cooling systems, power management, and workload distribution.

12 investors

Precision BioSciences develops gene-editing medicines using its proprietary ARCUS genome editing platform, which employs sequence-specific nuclease enzymes to insert, remove, or repair DNA in living cells to treat hard-to-treat conditions including rare genetic diseases and hepatitis B (HBV).

12 investors

Quanergy develops 3D LiDAR sensing systems and perception software for physical security, smart cities, and industrial automation. Its technology serves applications such as protecting critical infrastructure, monitoring traffic and crowds, and automating industrial processes for enterprise and Fortune 100 customers.

12 investors

Quantum Machines builds Hybrid Control systems that integrate quantum control units with classical compute, including the Pulse Processing Unit (PPU) and a development platform based on the QUA language. Its products serve quantum computing developers and researchers working across quantum technologies, with compatibility for stacks such as OpenQASM, Qiskit, and CUDA-Q.

12 investors

Rainmaker uses cloud seeding technology to combat water scarcity by generating freshwater at scale. The company operates in the climate tech and water security sector, positioning cloud seeding as a more efficient alternative to desalination and water pipelines.

12 investors

RISC Zero provides verifiable computation technology that lets anyone cryptographically confirm a computation's output is correct without recomputing it, while preserving privacy. It targets use cases such as proving financial transactions are performed correctly and compliantly, and helping technology companies close trust gaps in software supply chains.

12 investors

Satellite Vu captures thermal imagery from space for applications including environmental monitoring and infrastructure assessment. The company provides high-resolution nighttime and daytime thermal data with web-based and API access for customers analyzing heat signatures on Earth.

12 investors

Synthego develops CRISPR gene-editing and molecular diagnostics products, including custom CRISPR editors in mRNA or protein formats, base editors, and cell-free protein and RNA production systems. It serves researchers and cell and gene therapy developers in the biotechnology industry.

12 investors

UbiQD develops and manufactures quantum dot materials and products for controlled-environment agriculture, clean energy, and security applications. The company's first commercial product, UbiGro, is a luminescent layer that enhances crop yields in greenhouses by optimizing light spectrum through fluorescence technology.

12 investors

Universal Quantum develops quantum computers using trapped ion technology designed to solve complex computational problems in drug design, climate modeling, battery chemistry, and other fields. The company builds devices intended to operate reliably and deliver practical utility at scale.

12 investors

Volumetric builds living multicellular human tissues using 3D bioprinting technology that creates complex blood vessel networks, primarily to produce patient-specific tissues for drug safety and efficacy testing, basic biology research, and screening. The company aims longer term to produce functional tissue and organ replacements for damaged vital organs such as the lung, liver, pancreas, kidney, and heart.

12 investors

Aerska develops RNA interference (RNAi) medicines designed for targeted delivery across the blood-brain barrier to treat, delay, and prevent central nervous system and neurological diseases. The company combines next-generation RNA therapeutics, brain delivery technologies, and biomarker-guided precision medicine to silence disease-causing genes in the brain.

11 investors

Airspace Intelligence develops predictive software for mission-critical operations in defense and infrastructure sectors, serving large airlines and US government agencies. The company uses geospatial AI and machine learning to provide decision-makers with predictive capabilities rather than reactive visibility into complex operational environments.

11 investors

AON3D builds industrial 3D printers that print with advanced thermoplastics at a lower cost than prior options, and develops new materials for additive manufacturing. Its customers worldwide use the technology across applications including automotive tooling, aircraft interiors, foundry molds, prosthetics, and surgical oncology guides.

11 investors

Argospace provides launch and transportation services for spacecraft and satellites beyond low Earth orbit (LEO), including cislunar and interplanetary missions. The company operates reusable vehicles with dual-mode propulsion to serve satellite operators, space agencies, and exploration missions.

11 investors

ARIX combines robotics and data analytics to inspect and manage critical industrial assets. The company serves customers across industries seeking to improve safety and reduce maintenance costs through automated inspection solutions.

11 investors

Arvist provides an AI platform for warehouse operations that integrates with existing systems to automate claims management, detect errors, and improve supply chain efficiency. The company serves warehouse and operations teams seeking to optimize workflows without replacing existing infrastructure.

11 investors

Aurora Labs develops AI technology for understanding and managing complex embedded systems, AI infrastructure, and data-center environments. The company serves developers and technology teams across automotive, IoT, and data infrastructure sectors.

11 investors

Axonis Therapeutics is a biotechnology company developing small-molecule medicines that target KCC2, a mediator of inhibition in the brain, to treat neurological disorders such as epilepsy and pain. It translates discoveries from Boston Children's Hospital, Harvard and Laval University into central nervous system therapies.

11 investors

Black Semiconductor develops graphene-based Integrated Graphene Photonics chip technology that combines photonics and electronics on the same wafer to improve chip connectivity, performance, and energy efficiency. The company operates in the semiconductor industry and is building a 300mm pilot fabrication facility in Europe.

11 investors

Callosum is building heterogeneous AI intelligence, working across the full stack from silicon to algorithms to systems. The company is founded by people bridging neuroscience, computing, and AI.

11 investors