Deep Tech Startups

Voyager Technologies builds defense and space systems, including solid-fuel and electric propulsion, energetics (the only U.S. provider of black powder), radiation-hardened space electronics, guidance and navigation systems, lunar and long-duration spaceflight infrastructure, and signals-intelligence/spectrum-dominance software. It serves U.S. and international government agencies, defense primes, academia, and commercial and civil space programs.

8 investors

Wyvern develops high-resolution hyperspectral imaging satellites and delivers satellite-based earth observation data for model-based predictions. The company operates a satellite constellation in the space technology and remote sensing sector.

8 investors

ZaiNar develops a platform for Physical AI that uses existing wireless networks to provide real-time positioning and sensing without satellites, cameras, or dedicated infrastructure. The technology enables sub-meter accuracy positioning and time synchronization across healthcare, construction, and industrial operations.

8 investors

Adaption Labs builds adaptive AI systems that continually learn and adjust to specific industries, languages, and use cases, positioning itself against large monolithic, one-size-fits-all models. Its work spans dynamically shaped datasets, gradient-free continual learning, and reimagined human-AI interfaces.

7 investors

Affinia Therapeutics develops genetically engineered adeno-associated virus (AAV) therapies for treating genetic diseases, focusing initially on cardiovascular and central nervous system conditions. The company uses AI and structural modeling to redesign viral delivery vectors for one-time-dose genetic medicines across rare and prevalent diseases.

7 investors

ANYbotics develops autonomous robots that perform inspection and maintenance tasks in industrial facilities, particularly in energy, oil & gas, and manufacturing sectors. The robots are designed to replace hazardous, monotonous work while supporting customer goals in safety, sustainability, and digitalization.

7 investors

Apollo Atomics develops compact nuclear power systems designed for rapid deployment. The company builds power-dense reactors intended for commercial electricity generation.

7 investors

Archetype AI builds Physical AI for real-world operations, centered on Newton, a proprietary foundation model that fuses multi-sensor data to perceive and reason about physical environments. Its platform lets enterprises in construction, manufacturing, and telecommunications create and deploy Physical Agents for tasks like anomaly detection, machine monitoring, and safety, running from cloud to edge or on-premises.

7 investors

ARRIS is an advanced manufacturing technology company that uses its Additive Molding process to align continuous fibers, electronics, and metallic components into topology-optimized composite parts. It partners with companies in consumer goods, portable electronics, industrial, and transportation to produce lighter and stronger products at scale.

7 investors

Atomic Alchemy developed technology and facilities for producing radioisotopes for medical, industrial, and research applications, planning dedicated isotope-production reactors in Idaho. Acquired by Oklo in 2024.

7 investors

Aurora Labs develops AI technology for understanding and managing complex embedded systems, AI infrastructure, and data-center environments. The company serves developers and technology teams across automotive, IoT, and data infrastructure sectors.

7 investors

Berkeley Lights (now Bruker Cellular Analysis) develops the Beacon optofluidic system for single-cell functional analysis, enabling researchers to profile live single cells to discover therapeutic antibodies, interrogate T cells, identify cell therapies, and accelerate cell line development. Its platform serves biotech, pharma, and academic researchers across discovery, basic research, and translational research.

7 investors

bit.bio is a synthetic biology company that engineers human induced pluripotent stem cells into defined cell types for research, drug discovery, and cell therapy applications. The company markets cells and disease models through its ioCells brand for use in biomedical research and therapeutic development.

7 investors

Blykalla develops a first-of-a-kind lead-cooled small modular reactor (SMR) using a patented aluminum-alloyed corrosion-resistant steel, and has applied to build an advanced nuclear reactor park at Norrsundet, Sweden delivering around 330 MW of baseload power. The company originated as a spin-off from the Royal Institute of Technology in Stockholm and works in the advanced nuclear energy sector.

7 investors

Captura develops Direct Ocean Capture technology using bipolar membrane electrodialysis to remove CO₂ from the upper ocean and atmosphere. From its Pasadena facility, the company also manufactures high-performance membranes and electrodialysis stacks for carbon removal and other sustainability-focused industrial, resource, and energy applications.

7 investors

Cartography develops antibody-based cancer therapies using single-cell sequencing and computational biology to identify precise cellular targets. The company combines genomics data analysis with therapeutic design to create more targeted treatments for cancer patients.

7 investors

Clear Labs develops fully automated next-generation sequencing (NGS) platforms that process genomic data into insights for research and surveillance applications across infectious disease, food safety, and oncology. The company serves laboratories, food brands, healthcare systems, and diagnostic organizations.

7 investors

Code Metal builds AI-assisted code translation and modernization tools that use formal verification and program analysis to produce tested, standards-compliant, and portable code. It targets mission-critical industries such as aerospace, automotive, and defense, helping teams modernize legacy code, avoid chip vendor lock-in, and meet safety and compliance requirements.

7 investors

Cognichip develops Artificial Chip Intelligence (ACI), an AI system designed to accelerate semiconductor design by reducing design effort and time-to-market for chip manufacturers. The platform aims to address the hardware development bottleneck by automating chip design workflows and making the process more accessible to the semiconductor industry.

7 investors

Conductor develops AI algorithms and control software for quantum computing, helping researchers and engineers optimize qubit architectures and scaling in semiconductor-based quantum systems.

7 investors

Constellr builds and operates custom thermal-imaging satellites and an end-to-end system that measures surface temperature globally to deliver thermal intelligence on human activity, infrastructure load, and environmental stress. It targets defense operations and strategic planning, offering calibrated thermal measurements and analytics for mission readiness.

7 investors

Constructive Bio is a biotechnology company that rewrites the genetic code to give cells access to non-canonical amino acid building blocks, expanding the range of proteins that can be designed, engineered, and manufactured. Its platform aims to move novel molecules from research to industrial-scale production for applications ranging from medicines to advanced materials.

7 investors

Deepcell uses artificial intelligence and high-resolution imaging to analyze cell morphology for biological research and discovery. The company serves scientists and life science researchers across multiple biological domains.

7 investors

DustPhotonics develops silicon photonics chips (PICs) and an end-to-end SiPho platform with laser integration and fiber coupling, based on its proprietary L3C laser-attach technology. Its products provide optical connectivity for data centers and AI infrastructure across a range of transceiver architectures and data rates from 400G to 1.6T.

7 investors