/People

Eric Lefkofsky

InvestorUnicorn founder

Founder at Tempus · Investor at Lightbank · Co-founder at Pathos · Founder at Uptake Technologies

Chicago

Writes $500K – $5M checks · typically $1M

FoundedTempus$5.9BGroupon, Inc.PathosUptake Technologies

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About

Eric Lefkofsky is the founder and CEO of Tempus, a technology company applying artificial intelligence to healthcare and precision medicine, which he started in 2015 with a personal motivation tied to cancer. Over roughly 25 years he has co-founded a string of technology companies including Groupon, Mediaocean, Echo Global Logistics, InnerWorkings, and Pathos.AI. He is a founding partner of the venture fund Lightbank, which invests in disruptive technologies. Beyond building companies, he established the Lefkofsky Family Foundation with his wife Liz in 2006, teaches as an adjunct professor at the University of Chicago, and wrote the book Accelerated Disruption.

Contact· published on Eric's own website

Invests in

FintechHealthtechLogistics & Supply ChainMarketplacesSaaS

Beyond investing

Founded
Founded and leads Tempus, a company applying AI to precision medicine and cancer care. Co-founded Groupon, where he is Chairman. Co-founded Mediaocean, a media procurement technology provider. Co-founded Echo Global Logistics, a transportation and logistics outsourcing firm. Co-founded InnerWorkings, a managed print and promotional solutions provider. Co-founded Pathos.AI, an AI-enabled drug company.
Education
Graduated from the University of Michigan. Received his Juris Doctor from the University of Michigan Law School.
Boards
Serves as a Trustee of Steppenwolf Theatre Company. Serves as a Trustee of Lurie Children's Hospital of Chicago. Serves as a Trustee of The Art Institute of Chicago. Serves as a Trustee of World Business Chicago.
Charities
Established the Lefkofsky Family Foundation with his wife Liz in 2006 to support education, human rights, and civic causes.
Awards
Author of the book Accelerated Disruption.
Family
Married to Liz Lefkofsky, with whom he founded the family foundation.

Mentioned above: the University of Michigan mafia → · the University of Michigan Law School mafia →

From Eric's own website — common ground for a warm intro.

Co-founder at Pathos

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Co-founders at Pathos

ELEric Lefkofky
Eric LefkofkyExecutive Officer, Director
RFRyan Fukushima
Ryan FukushimaCo-founder

Founder at Uptake Technologies

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Co-founders at Uptake Technologies

BK
BRAD KEYWELLExecutive Officer, Director

Founder at Tempus

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Deals · 1

TempusLed round

via Lightbank · filed Dec 2020

Attribution from SEC filings, press coverage, and firm rosters.

Other disclosed investments

Led

Lightbank

Board seats

Groupon

Investor

60moArkARTABabbaCo (acquired by Barefoot Books in 2014)BasketBeachMintBeautylishBenchPrepBenzingaBetterfly (ACQUIRED)Beyond GamesBlueprintBonfaireBoom SupersonicBoomerangBoostableClasskickClever SenseCloudbotclusterFlunkCoffee Meets BagelCrowdriseDa'at TechnologiesDoubledutchDoughDraftDayDRIVINEcho Global LogisticsEventUpExicureFiverrFoodaFrank & OakFreeAgentGenus OncologyGetGoingGrouponHatch LoyaltyHighgroundInflowInnerWorkingsLeapLightswitchMediaoceanMonthlysMyCabbagemyReteNeedleNeighborhoodsNubundleoBazOhanaOnSwipeOpenChimePathos.AIpawngoProSkyQuibbQwikiReverb.comRiseSkyVu ARSnapsheetSocialKatySoCore EnergySoundsupplySpirit ShopSpotHeroSprout Social, Inc.SunnyBumpSuper.comTagkastTakeLessonsTalentBinTapitureTechstarsUdemyUptake TechnologiesVenturebeatwalkbyWhere I've BeenYellowsmithZaarlyZeelZest Health App

Sources: the investor's own website · curated public sources.

Recent posts consist of Tempus quarterly CEO earnings letters detailing revenue, diagnostics and data-business growth, and an essay arguing that Tempus's large multimodal, longitudinal healthcare dataset can train AI models to predict patient outcomes.

Colleagues at Lightbank

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Frequently asked questions

Who is Eric Lefkofsky?
Eric Lefkofsky is the founder and CEO of Tempus, a technology company applying artificial intelligence to healthcare and precision medicine, which he started in 2015 with a personal motivation tied to cancer. Over roughly 25 years he has co-founded a string of technology companies including Groupon, Mediaocean, Echo Global Logistics, InnerWorkings, and Pathos.AI. He is a founding partner of the venture fund Lightbank, which invests in disruptive technologies. Beyond building companies, he established the Lefkofsky Family Foundation with his wife Liz in 2006, teaches as an adjunct professor at the University of Chicago, and wrote the book Accelerated Disruption.
Where does Eric Lefkofsky work?
Eric Lefkofsky is Founder of Tempus and Investor at Lightbank and Co-founder at Pathos and Co-founder at Uptake Technologies.
What does Eric Lefkofsky invest in?
Eric Lefkofsky invests in Fintech, Healthtech, Logistics & Supply Chain, Marketplaces, SaaS.
What check size does Eric Lefkofsky write?
Eric Lefkofsky typically writes checks of $500K – $5M.
What companies did Eric Lefkofsky found?
Eric Lefkofsky founded Tempus, Groupon, Inc., Pathos, Uptake Technologies.
What boards does Eric Lefkofsky sit on?
Eric Lefkofsky holds tracked board seats at Groupon.
What companies has Eric Lefkofsky invested in?
Investments tracked here include Lightbank, Tempus, 60mo, Ark, ARTA, BabbaCo (acquired by Barefoot Books in 2014), Basket, BeachMint, Beautylish, BenchPrep, Benzinga, Betterfly (ACQUIRED), and 76 more.
What awards has Eric Lefkofsky received?
Author of the book Accelerated Disruption.
What has Eric Lefkofsky written?
Eric Lefkofsky has 1 tracked post on lefkofsky.com, including "Q2 Earnings 2026: Letter from the CEO".
Does Eric Lefkofsky lead rounds?
Yes — Eric Lefkofsky has led 2 tracked investments.

Founder mafias

About this profile. Compiled from public sources — Lightbank's own website, regulatory filings, press coverage and public professional profiles — and summarised by Fundraising Fox; every fact is kept with where it came from. Spotted an error, or would rather not be listed? Email privacy@fundraisingfox.com · How we build profiles · Your rights