Mental Health Startups

MindMed is a biotech company developing psychedelic-based therapeutics, including a proprietary orally disintegrating LSD tablet (DT120) and an R-enantiomer of MDMA (DT402), to treat brain health disorders such as generalized anxiety disorder, major depressive disorder, PTSD, and autism spectrum disorder. Its work targets patients in the U.S. and remains in clinical/preclinical stages, not yet FDA-approved.

5 investors

MindRight Health provides culturally affirming mental health support through a community-based platform and network of peer supporters. The company serves individuals seeking accessible mental health care outside traditional systems.

5 investors

Motivo provides clinical supervision and support services for newly graduated therapists entering the mental health workforce, helping behavioral health organizations address the shortage of qualified mental health providers.

5 investors

MycoMedica Life Sciences is a biopharmaceutical company developing psilocybin-based treatments for mental health and neurodegenerative disorders. It conducts non-clinical and human clinical studies of low-dose psilocybin, with an initial focus on Premenstrual Dysphoric Disorder and other neuropsychiatric conditions such as OCD, Opioid Use Disorder, and Parkinson's Disease.

5 investors

Netsmart provides behavioral health information technology solutions and advocacy services supporting the expansion of Certified Community Behavioral Health Clinics and integrated mental health care delivery. The company engages in legislative advocacy and industry coalition work to advance behavioral health IT infrastructure and financing policies.

5 investors

Octave is a mental health practice platform that connects licensed therapists with patients seeking in-network mental health care. The company handles insurance credentialing, billing, scheduling, and client matching to support therapists and expand access to effective mental health treatment.

5 investors

Oliva is a therapy and professional coaching platform for companies, offering individual and group coaching, full-spectrum therapy, and manager support through a flexible plan. It serves employers and HR teams looking to support employee mental health and build high-performing team dynamics, aggregating anonymised session data into insights on common challenges and skill gaps.

5 investors

Qualifacts provides AI-powered electronic health record (EHR) software, data tools, and interoperability services for behavioral health agencies, both non-profit and for-profit. Its offerings support clinical documentation, workflow automation, data insights, and secure data exchange for clinicians and administrators across the United States.

5 investors

Outro provides digital mental healthcare focused on safely discontinuing psychiatric medications through individualized tapering plans based on hyperbolic deprescribing research. The platform serves patients seeking evidence-based support and medical guidance for managing antidepressant withdrawal.

5 investors

pirkx provides an employee benefits and wellbeing membership platform covering mental and emotional support, 24/7 private GP access with prescription delivery, and financial savings tools organised around five pillars of wellbeing. It is offered to employers for their staff and members, with UK contact details.

5 investors

Psyrin builds a behavioral health platform centered on Mira, a conversational AI voice agent that conducts structured pre-assessment intakes with clients via kiosk or phone before their session, then generates scored screens, risk flags, and real-time documentation pushed into the clinic's EHR. It targets behavioral health clinics and assessors to increase billable assessment capacity without adding staff.

5 investors

Pulse is a smart wearable ring paired with a mobile app that delivers gentle micro-vibrations to remind users to pause, breathe, and practice mindfulness throughout the day, including headphone-free guided meditation. It also offers expert-led self-development courses and a Pulse+ subscription with additional modes for habit-building and digital detox.

5 investors

Rosebud is a journaling app with AI-powered features including entry reflection, weekly reports, and personalized content recommendations. It serves individuals seeking guided journaling and wellness tracking through mobile and voice-based interfaces.

5 investors

Soulside builds AI-driven tools for clinicians in behavioral healthcare, including automated clinical documentation and real-time insights. The platform is aimed at behavioral health programs and providers.

5 investors

Talkiatry is a telehealth platform that connects patients with psychiatrists for remote mental health care. The platform serves patients seeking faster psychiatric access and doctors aiming to provide care more flexibly.

5 investors

TRIP designs functional beverage and supplement products formulated with botanical ingredients intended to help users manage stress, improve sleep, and support overall wellbeing. The company targets consumers seeking natural products for daily mental health and relaxation support.

5 investors

Two Chairs matches individuals with personalized mental health care, including therapy and psychiatry services, using a technology-enabled platform designed to improve access and treatment outcomes. The company serves people seeking affordable, evidence-based mental health care.

5 investors

UpLift provides mental health and wellness services for college students through a referral platform connecting them with licensed providers and psychiatric care. The company offers flexible subscription and prepay models to ensure students can access treatment regardless of insurance status.

5 investors

Upswing offers a wraparound student services platform that supports higher education students with academic help, mental health, basic needs, advising, and on-demand information to improve retention rates. It is marketed to colleges and universities as a retention and tuition-revenue strategy.

5 investors

Wave provides mental health care through digital tools, coaching, and AI support, offering personalized, science-backed therapy alternatives. It aims to make high-quality mental health care accessible and affordable for individuals.

5 investors

Wysa for Teams is a mental health SaaS product that delivers emotional wellbeing support to organizations with 200 employees or less through self-guided exercises, anonymous access to reflection spaces, and resources based on cognitive behavioral approaches.

5 investors

Amae Health provides in-person, coordinated care for people living with severe mental illness (SMI), combining clinical treatment with a precision medicine platform built on longitudinal, data-driven insights. It works with institutions such as Cedars-Sinai, NewYork-Presbyterian, and Massachusetts General Hospital to improve how SMI is diagnosed and treated.

4 investors

Atai Beckley develops rapid-acting, durable, and convenient therapies for mental health conditions where patients currently have limited treatment options. The company focuses on evidence-based drug development aimed at improving patient outcomes in mental health care.

4 investors

Avela Health provides virtual autism evaluations and therapy for children, teens, young adults, and their families, with services delivered by Master's or doctoral-level clinicians via video. It offers age-specific therapy programs, group support, school coordination, and specialty care, primarily serving families in New Jersey, Pennsylvania, and South Carolina.

4 investors