Medical Devices Startups

Aspect Biosystems is a Canadian biotechnology company developing Bioprinted Tissue Therapeutics—implantable engineered tissues designed to replace, repair, or supplement biological function—for the treatment of diseases such as type 1 diabetes. It operates in the regenerative medicine field and has partnered with pharmaceutical companies including Novo Nordisk.

10 investors

Aura Biosciences develops Virus-Like Drug Conjugates (VDCs), a platform using Virus-Like Particles conjugated with drugs or loaded with nucleic acids to target solid tumors. Its lead focus is treating choroidal melanoma, a rare ocular cancer for which no first-line drug therapies currently exist.

10 investors

Axonis Therapeutics is a drug discovery company developing first-in-class therapies for currently incurable neurological disorders. It focuses on advancing treatments for patients with neurological diseases.

10 investors

Boston Scientific supports external researcher-initiated studies through its Investigator Sponsored Research program, which funds independent investigations addressing disease understanding and treatment gaps of interest to the medical community.

10 investors

Mytos develops automated manufacturing technology for regenerative medicines, specifically targeting the production of stem cell-derived therapies to make treatments for conditions like Parkinson's, blindness, and spinal cord injury accessible and affordable to patients.

10 investors

Ochre Bio develops RNA therapeutics and drug discovery platforms targeting liver disease, combining proprietary human liver datasets with AI-driven causal prediction and human tissue validation models. The company aims to address the global shortage of liver transplants by developing new treatment options for liver fibrosis and cirrhosis.

10 investors

Proscia provides a digital pathology software platform that converts glass microscope slides into high-resolution digital images for viewing, management, and analysis by pathologists and research teams. The platform enables clinical laboratories and life sciences organizations to improve workflow efficiency, support remote collaboration, and integrate artificial intelligence tools for quantitative tissue analysis and biomarker detection.

10 investors

ReCode develops mRNA and gene correction therapeutics for genetic diseases, using proprietary lipid nanoparticle technology to deliver treatments to specific organs. The company is focused on rare genetic conditions including cystic fibrosis and primary ciliary dyskinesia.

10 investors

Redcliffe Labs is a diagnostic laboratory platform in India offering at-home and lab-based health tests with personalized health packages, AI-powered report analysis, expert consultations, and genomic testing services. The company targets consumers seeking affordable, accurate diagnostics with personalized health guidance and family-focused healthcare solutions.

10 investors

Restore Vis is a life sciences company founded by a vitreoretinal surgeon and clinician scientist focused on addressing inflammation, aging, neurodegeneration and angiogenesis through translational research from drug discovery to clinical trials. The company develops treatments for ophthalmology and vision-related conditions.

10 investors

Cytovale develops microfluidic deformability cytometry technology for immune response diagnostics, with a focus on early detection and diagnosis in hospital settings. The company serves healthcare systems and clinicians with diagnostic instruments and solutions.

9 investors

Aidoc develops an enterprise AI platform for hospitals that integrates clinical algorithms into existing workflows to prioritize patient findings and activate care teams across multiple departments. The platform serves healthcare systems and supports radiologists, clinicians, and other specialists in improving diagnostic efficiency and patient outcomes.

9 investors

Alpha-9 Oncology develops radiopharmaceuticals for cancer treatment, with a portfolio of molecules in clinical and preclinical development. The company serves patients with cancer through novel drug candidates advancing in clinical trials.

9 investors

Apheris provides a platform enabling large global life sciences organizations to collaborate on sensitive, proprietary data and jointly train machine learning models on distributed datasets while maintaining privacy across teams, borders, and organizations.

9 investors

DELFI Diagnostics develops FirstLook Lung, a blood-based laboratory test for lung cancer screening that identifies genome-wide alterations in individuals eligible for screening. The test offers an alternative to low-dose CT imaging for patients meeting USPSTF criteria and is made available to health systems, primary care providers, and lung screening programs.

9 investors

Diligent Robotics develops AI-powered robot assistants for healthcare settings, focusing on mobile manipulation and social intelligence to help hospital staff with routine non-patient-facing tasks. The company's flagship product, Moxi, enables clinical staff to dedicate more time to direct patient care.

9 investors

FIGUR8 is an FDA-registered platform that provides objective, actionable insights for musculoskeletal health diagnosis and treatment. The platform originated from collaboration between MIT scientists, Massachusetts General Hospital, and the Boston Red Sox, and is now adapted for use across any point of care.

9 investors

Bristol Myers Squibb is a biopharmaceutical company that develops and delivers medicines across oncology, hematology, neuroscience, immunology, and cardiovascular disease areas. The company focuses on creating transformative treatments for patients in high-need therapeutic categories.

9 investors

Juvena Therapeutics develops biologics derived from human secreted proteins to treat aging-related diseases, using AI-enabled drug discovery to identify tissue-restorative therapeutics for muscle and metabolic disorders.

9 investors

Leiters Health is an FDA-registered 503B outsourcing facility that produces ready-to-administer compounded and repackaged sterile medications, including pre-filled syringes, IV bags, and ophthalmic solutions. It serves hospitals, health systems, surgery centers, clinics, and physician offices across the United States, helping address medication shortages and support pharmacy operations.

9 investors

Medable provides a cloud-based platform for clinical research that uses AI and digital tools to accelerate the development of therapies by improving the quality, reach, and efficiency of clinical trials. The platform serves pharmaceutical sponsors, contract research organizations (CROs), and clinical research sites.

9 investors

Octant is a therapeutics company that develops small molecule drugs to treat protein misfolding diseases. Using synthetic biology, high-throughput chemistry, and AI/ML, the company's Navigator platform studies how target proteins interact within living human cells to enable drug discovery for rare diseases and oncology.

9 investors

Helicons develops a peptide-based therapeutic platform designed to target intracellular proteins previously considered undruggable by combining the specificity of antibodies with the cell-penetrating properties of small molecules. The platform uses AI and simulation to engineer helical peptides with non-canonical amino acids for precision binding across a range of therapeutic applications.

9 investors

ShiraTronics is a medical device company developing an implantable device to treat chronic migraine disease. It is a privately held company operating in the medical device and healthcare industry.

9 investors