Siren Care
500 Global '16Plug and Play VenturesSan Francisco, US · Founded 2016 · 28 employees on LinkedIn · 11 known investors
Siren develops technology for early detection of diabetic foot ulcers to reduce injury risk. The company serves healthcare providers and patients managing diabetes.
Also known as Siren · Siren Socks
Founders & leadership
Siren Care was founded in 2016 by Ran Ma, Jie Fu, and Henk Jan Scholten.
Investors · 11
Company profile
researched Aug 2026Siren Care develops Siren Socks, wearable socks that continuously measure foot temperature to help identify early signs of injury in people living with diabetes. Rising foot temperature is used as an indicator of developing inflammation, which may signal an injury that could progress to a diabetic foot ulcer. The company positions the product as a way to reduce ulcer risk through earlier detection.
The offering combines the socks with a monitoring service: licensed nurses review the temperature data for signs of inflammation and call patients regularly to check on their health, while providers are alerted to potential injuries and decide whether a clinic visit is warranted. The socks are designed for daily wear and require no smartphone and no charging; they are machine washable and are replaced automatically as they wear down. Siren cites published research (Lavery et al., Diabetes Care, 2004) indicating that home temperature monitoring has been shown to reduce diabetic foot ulcers by up to 87.5%.
Business model
Siren supplies its temperature-sensing socks together with an ongoing remote monitoring service staffed by licensed nurses, with worn socks replaced automatically, and it works alongside providers who receive alerts and manage patient care.
Traction
The company publishes testimonials from a patient with type 1 diabetes who credits Siren notifications with catching Charcot foot symptoms, and from a Bay Area podiatrist whose patients use the socks for prevention of diabetic foot sores.
▸Full profile — market position, technology, go-to-market
Market position
Siren focuses on early detection of diabetic foot ulcers, a condition it describes as affecting more than 30% of people with diabetes over their lifetime, with 10% of those ulcers resulting in amputation.
Technology
Socks with embedded sensing that continuously measure foot temperature as an early indicator of inflammation and injury; the design requires no smartphone connection and no charging, and the socks are machine washable.
Go-to-market
Siren addresses both patients and providers directly through separate paths on its website, and cites podiatrist users of the product.
People living with diabetes who are at risk of foot ulcers, and the healthcare providers such as podiatrists who manage their foot care.
Compiled by commissioned research from 1 cited public sources — announcements, filings, and press listed under research sources below.
Key figures
latest reportedCompany-reported or press-reported figures, each dated to when it was claimed — not independently audited.
Competitors · 2
by search overlapCompanies competing with Siren Care for the same Google search keywords, organic and paid, via search-intersection analysis.
▸Research sources · 1
primary sources listed
- Siren Caresiren.care · web
1 public sources were cited for this profile; the first-party ones are listed here.
Frequently asked questions
- What does Siren Care do?
- Siren makes temperature-sensing socks with nurse monitoring to detect early signs of diabetic foot injury.
- Who founded Siren Care?
- Siren Care was founded by Ran Ma, Jie Fu, Henk Jan Scholten in 2016.
- Who are Siren Care's investors?
- Siren Care's investors include 500 Global, Aloft VC, Beni Venture Capital, DCM Ventures, Flucas Ventures, HCVC, Manta Ray Ventures, Mighty Capital and 3 more.
- Where is Siren Care headquartered?
- Siren Care is headquartered in San Francisco, US.









