Deep Tech Startups
5,883 companies tagged Deep Tech, with their investors and founders.
Koloma explores and produces natural hydrogen to support global decarbonization efforts. The company uses proprietary data and technology to identify hydrogen sources in the United States and globally, positioning the resource as a cost-competitive, reliable clean energy source for industrial and energy applications.
9 investors
Medra builds robotic systems integrated with AI, computer vision, and natural language processing to automate data collection for life science research. The company serves biotech and academic research labs seeking high-precision, large-scale experimental data collection.
9 investors
Metalenz develops metasurface optics technology for optical sensing in consumer and industrial devices. The company commercializes metalenses—miniaturized optical components that enable new sensing capabilities in smartphones, automotive systems, and medical devices.
9 investors
Natural builds payment infrastructure ("rails") designed for AI agents to execute transactions autonomously. The company targets the emerging agentic payments market, serving customers who deploy AI agents that need to make payments.
9 investors
Neurophos develops photonic AI accelerator chips (the OPU) that use photonic tensor cores to deliver high compute throughput at low power draw, aiming to compress a full GPU rack into the size and power of a single GPU. The company targets large-scale AI compute infrastructure with a focus on energy efficiency.
9 investors
Octant is a therapeutics company that develops small molecule drugs to treat protein misfolding diseases. Using synthetic biology, high-throughput chemistry, and AI/ML, the company's Navigator platform studies how target proteins interact within living human cells to enable drug discovery for rare diseases and oncology.
9 investors
Helicons develops a peptide-based therapeutic platform designed to target intracellular proteins previously considered undruggable by combining the specificity of antibodies with the cell-penetrating properties of small molecules. The platform uses AI and simulation to engineer helical peptides with non-canonical amino acids for precision binding across a range of therapeutic applications.
9 investors
Parallel Bio develops human immune organoids and computational tools to predict drug efficacy across diverse patient populations, replacing animal testing in drug discovery. The company aims to accelerate pharmaceutical development and reduce clinical trial failure rates through human-first biological prediction models.
9 investors
Protocol Labs is an innovation network connecting over 750 tech organizations developing breakthrough technologies across web3, AI, AR, VR, BCI, hardware, and related fields. Organizations collaborate to solve shared problems and accelerate R&D across technological frontiers.
9 investors
Quantinuum develops quantum computers and quantum software solutions for applications in drug discovery, healthcare, materials science, cybersecurity, and energy. The company operates as an integrated quantum technology platform serving enterprise and research customers globally.
9 investors
Quantum Machines builds Hybrid Control systems that integrate quantum control units with classical compute, including the Pulse Processing Unit (PPU) and a development platform based on the QUA language. Its products serve quantum computing developers and researchers working across quantum technologies, with compatibility for stacks such as OpenQASM, Qiskit, and CUDA-Q.
9 investors
Radian Aerospace is developing fully reusable spaceflight vehicles, including Radian One, a single-stage-to-orbit mission platform for routine access to Low Earth Orbit, and R3V, a reusable reentry capsule for hypersonic testing and rocket cargo. The company builds launcher-agnostic vehicles configurable for cargo, experiments, or custom payloads in the space industry.
9 investors
RISC Zero provides verifiable computation technology that lets anyone cryptographically confirm a computation's output is correct without recomputing it, while preserving privacy. It targets use cases such as proving financial transactions are performed correctly and compliantly, and helping technology companies close trust gaps in software supply chains.
9 investors
Rocket Lab develops launch vehicles and space systems for commercial space access and satellite deployment. The company provides small-to-medium lift launch services and spacecraft for government and commercial customers.
9 investors
Runway builds AI models that simulate the world by merging art and science, pioneering general-purpose multimodal simulators focused on applications in robotics, scientific discovery, and disease modeling.
9 investors
SEEQC develops a digital quantum computing platform that integrates the core functions of a quantum computer—including qubits and classical control logic—onto superconducting cryogenic chips, aiming to scale qubits without added complexity. The company targets partners and customers in quantum computing and AI, positioning its architecture for large-scale quantum data centers.
9 investors
Siren develops technology for early detection of diabetic foot ulcers to reduce injury risk. The company serves healthcare providers and patients managing diabetes.
9 investors
Synthego develops CRISPR gene-editing and molecular diagnostics products, including custom CRISPR editors in mRNA or protein formats, base editors, and cell-free protein and RNA production systems. It serves researchers and cell and gene therapy developers in the biotechnology industry.
9 investors
UbiQD develops and manufactures quantum dot materials and products for controlled-environment agriculture, clean energy, and security applications. The company's first commercial product, UbiGro, is a luminescent layer that enhances crop yields in greenhouses by optimizing light spectrum through fluorescence technology.
9 investors
Universal Quantum develops quantum computers using trapped ion technology designed to solve complex computational problems in drug design, climate modeling, battery chemistry, and other fields. The company builds devices intended to operate reliably and deliver practical utility at scale.
9 investors
Verge Labs builds AI models trained on multimodal human patient data to predict drug targets and patient populations for clinical development, primarily in neuroscience and central nervous system (CNS) disease. The company applies frontier AI techniques to drug discovery for life sciences and pharmaceutical development.
9 investors
Airspace Intelligence develops predictive software for mission-critical operations in defense and infrastructure sectors, serving large airlines and US government agencies. The company uses geospatial AI and machine learning to provide decision-makers with predictive capabilities rather than reactive visibility into complex operational environments.
8 investors
Amogy develops patented ammonia cracking technology that converts ammonia into electric power for hydrogen fuel cells and engines, targeting decarbonization of heavy industries including transportation and maritime. The company offers modular ammonia-to-power systems and high-efficiency catalysts as alternatives to diesel and hydrogen fuel solutions.
8 investors
Arvist provides an AI platform for warehouse operations that integrates with existing systems to automate claims management, detect errors, and improve supply chain efficiency. The company serves warehouse and operations teams seeking to optimize workflows without replacing existing infrastructure.
8 investors