Deep Tech Startups

Nomic offers an end-to-end protein profiling service built on its nELISA technology, quantifying up to 1000 informative proteins with absolute quantification for research studies. It targets researchers doing proteomics work, aiming for high-throughput, low-cost profiling in the biotech and life sciences market.

7 investors

Normal Computing develops software and hardware infrastructure optimizing AI models for physical systems through custom silicon design and advanced EDA tools. The company works with semiconductor design and manufacturing institutions to align hardware architecture with the computational demands of modern AI workloads.

7 investors

NuCurrent designs and licenses wireless power and NFC charging architecture for wearables, hearables, and ambient devices, working with product manufacturers to integrate coil, silicon, firmware, and thermal design. The company holds 450+ global patents and offers GenA, an applied-AI design platform for developing wireless power systems.

7 investors

Numerion Labs develops machine learning algorithms for drug discovery, combining computational chemistry, structural biology, and medicinal chemistry. It builds AI-driven platforms aimed at accelerating the identification of new medicines.

7 investors

Nurix Therapeutics develops protein degrader-based medicines using proprietary DEL-AI discovery technology to address cancer and autoimmune diseases. The company applies targeted protein degradation to overcome limitations of conventional therapeutic approaches.

7 investors

Omen provides continuous fluid analysis sensors that monitor the health of critical hardware in real time, detecting equipment failures before they occur across data centers and industrial machinery.

7 investors

oneNav develops small, low-power L5-band GNSS positioning technology for military, government, commercial, and consumer applications such as drones, trackers, aviation, and consumer devices. The company designs GNSS receiver hardware and software focused on accuracy and reliability using modern satellite signals.

7 investors

Optimum applies Random Linear Network Coding (RLNC) to speed up blockchain data propagation, encoding transactions, blocks, and data blobs into resilient packets to reduce latency and bandwidth use. Its tools target Ethereum validators, node operators, and high-performance blockchains, with a network where operators run nodes to monetize bandwidth in a "latency economy."

7 investors

Orca AI applies computer vision and deep learning to maritime shipping, providing situational awareness and automation tools to help commercial vessels navigate more safely and operate more efficiently. The company builds technology aimed at moving the shipping industry toward smart and autonomous ships.

7 investors

Osmoses develops a membrane technology for purifying and separating gas molecules, aimed at making industrial gas separation processes more energy-efficient. It targets industrial separation applications tied to the energy transition and decarbonization.

7 investors

Outerport automates the design of electrical and control systems within heavy industrial equipment, using AI agents to convert specifications into verified CAD drawings and structured design models. The platform serves manufacturers and OEMs building complex machines across semiconductors, process plants, and mechanical equipment.

7 investors

Parallel Domain creates synthetic data for autonomous systems development, addressing data generation bottlenecks in the industry. The company serves autonomous vehicle and robotics companies through its PD Replica simulation and synthetic data platform.

7 investors

Parallel Wireless develops open radio access network (RAN) software and solutions for telecommunications operators. The company provides cost-effective, resilient LTE and 5G network architecture for wireless communications.

7 investors

PassiveLogic develops AI systems for autonomous building control and operations. The company provides a Physical AI stack to autonomously manage building infrastructure, energy consumption, and operations.

7 investors

Persephone Biosciences develops live biotherapeutic products that modulate the metabolism of gut microbes for disease prevention and treatment, with a focus on cancer. It applies systems and synthetic biology to study the gut microbiome.

7 investors

Phantom AI develops a modular, software-based autonomous driving stack, including deep learning computer vision (PhantomVision), sensor fusion (PhantomFusion), and vehicle control (PhantomDrive) for Euro NCAP-compliant ADAS and level 2/3 autonomy. Its main customers are Tier 1 automotive suppliers and OEMs building advanced driver assistance systems.

7 investors

Phantom Neuro develops neurotechnology for human-machine interaction, with a focus on applications for limb-loss and amputee populations. The company works in the neurotech and medical device space, drawing on neuroscience, robotics, and human performance research.

7 investors

PlasmaLeap builds plasma-based, zero-emissions chemical reactors for the synthesis of green fuels and chemicals and for treating hazardous industrial waste. It serves industrial and academic research customers within the Power-to-X and green chemical production space.

7 investors

Prellis Biologics runs an antibody discovery platform that uses two-photon laser-bioprinted human immune organoids combined with machine learning to identify fully human antibody therapeutics. It develops a portfolio of antibody drug candidates across multiple disease areas and partners with biotech and pharmaceutical companies.

7 investors

Pretzel Therapeutics develops therapeutics targeting bioenergetic dysfunction and mitochondrial disease by addressing defects in mitochondrial DNA function and gene expression. The company leverages expertise in mitochondrial biology and drug discovery to create treatments for diseases associated with mitochondrial dysregulation.

7 investors

Probius develops Quantum Electrochemical Spectroscopy (QES), a label- and reagent-free electrochemical sensing technology that detects and quantifies thousands of analytes—proteins, metabolites, and cells—from microliter-scale biological samples in about 30 minutes. The platform generates digital representations of biological specimens and cloud-based multiplex assays intended to feed AI models of biology for biomarker discovery, drug development, and bioproduction quality control.

7 investors

Project Omega recycles spent nuclear fuel to rebuild the domestic nuclear fuel cycle, using chemistry processing to remove key isotopes and develop new products for the nuclear economy. It also builds transportable, long-duration nuclear power systems, such as its Zero Day Hybrid Power System, for national security, space, and maritime missions in the United States.

7 investors

Prometheus uses solar and wind power to capture CO2 and water from the air and convert them into zero net carbon electrofuels—gasoline, diesel, and jet fuel that work in existing engines without modification. The company targets transportation fuel markets, including aviation, with price-competitive drop-in fuels.

7 investors

Proteinea uses proprietary AI models and computational tools to engineer antibodies, focusing on rational design of antibody Fc domains for improved efficacy, half-life, and targeted biodistribution. It combines AI-driven design frameworks with wet-lab validation to develop Fc-optimized antibody scaffolds for therapeutic development.

7 investors