Deep Tech Startups

Skorpios Technologies manufactures photonic integrated circuits and provides foundry services for silicon photonics. The company serves telecommunications, data center, and high-speed optical communication markets.

2 investors

SKY ENGINE AI operates a Synthetic Data Cloud platform that generates synthetic images with pixel-perfect annotations—such as 3D keypoints, semantic masks, bounding boxes, depth maps, and normal maps—along with sensor simulation to train computer vision models. It serves industries including automotive (driver monitoring), robotics, manufacturing/quality control, medical imaging, defense/security, and drones/UAVs.

2 investors

SkyDrive develops compact electric vertical takeoff and landing (eVTOL) aircraft, including its SD-05 model, designed to launch from small spaces such as building rooftops and parking areas for everyday urban air travel. The Japanese company targets use cases like easing urban congestion, enabling tourism access, and providing rapid transport during disasters and medical emergencies, working with regional service providers across Japan and internationally.

2 investors

Skyfora develops weather forecasting technology using AI-driven GNSS tomography and GPS-based radiosondes to close gaps in weather data. The company works at the intersection of atmospheric science and AI to support climate change adaptation.

2 investors

SkyServe provides edge computing and AI model management software for satellite operators to deploy AI-powered earth observation applications on satellites. The platform reduces latency, downlink costs, and data processing demands for geospatial analytics providers and government organizations.

2 investors

smallTalk develops technology products that support early childhood brain development through language exposure. The company targets parents and caregivers of infants and young children in the early development market.

2 investors

Soctera develops nitride semiconductor power amplifiers that use a thinner semiconductor stack to deliver higher power density and lower operating temperatures for 5G telecom, SATCOM, and radar systems. Spun out of Cornell University's School of Electrical and Computer Engineering, the company targets telecommunications, radar, electronic warfare, and satellite communication networks.

2 investors

SOINN develops compact, low-computation AI based on its patented "artificial brain SOINN" technology to add intelligence to devices, equipment, and information systems. Its recent focus areas include energy management, anomaly detection, and control of equipment and robots for business clients.

2 investors

Soley Therapeutics develops proprietary imaging, AI, and automation technology to analyze cellular responses to stress and drug exposure, enabling the discovery of novel medicines and therapeutic mechanisms.

2 investors

Solinide Photonics develops silicon nitride optical microcomb chips that replace multiple discrete lasers with a single integrated multiwavelength source for Co-Packaged Optics (CPO), reducing power, cost, and footprint. Its technology targets datacenter and AI infrastructure interconnects, along with 5G/6G networks and quantum communications.

2 investors

SoloPulse develops advanced physics-based and AI-powered systems for threat detection and intelligence gathering, offering SIGMA™ for payload-based situational awareness and NOVA™ for synthetic aperture radar processing across unmanned and satellite platforms.

2 investors

SOLVE Chemistry runs an automated lab with high-throughput data collection and machine learning to generate FAIR kinetic data, quantitative yield insights, and micro-kinetic models for organic synthesis. It serves pharmaceutical and agrochemical companies looking to speed up process development and scale-up of chemical reactions.

2 investors

SomaLogic develops proteomics tools that help researchers measure protein function and study human biology across a range of scientific applications. The company is now part of Illumina, combining proteomics with genomics for a multiomics approach.

2 investors

Sonair develops ADAR One, a safety-certified 3D ultrasonic sensor that uses acoustic detection and ranging to detect people and obstacles in a full 3D volume for autonomous robots and static machine work scenes. The sensor targets robotics, automation, and industrial customers in warehouses, factories, logistics, retail, and hospital environments.

2 investors

Soundpays offers TAP (Thought-to-Action Protocol), a technology that connects user intent to instant actions across in-person and on-screen surfaces, aiming to let people complete actions without leaving the moment. It is positioned as an engagement and value-capture layer for businesses seeking to convert attention into outcomes.

2 investors

South 8 Technologies develops LiGas, a patented liquefied gas electrolyte for lithium-ion battery cells that operates across an extreme temperature range (-60 to +60°C) with added safety and fast-charge benefits. It supplies finished cells for defense and specialty markets and an electrolyte integration kit for cell manufacturers, with production in San Diego, California.

2 investors

Space Copy develops additive manufacturing and printing systems designed for extreme environments, including remote terrestrial construction and off-world applications. The company serves defense, space, mining, and disaster response sectors with solutions for on-site fabrication of infrastructure and tooling.

2 investors

SpaceCadet Ventures is a marketing and growth-support firm that works with founders of science- and technology-driven startups, offering story sprints to develop vision, decks, and growth, along with partner support in design, PR, and community.

2 investors

Spaceship provides e-commerce logistics software and fulfillment services for online DTC brands, including order management, real-time shipping quotes, shipping automation, customs clearance guidance, and outsourced warehousing. It integrates with over 100 logistics partners and platforms and operates warehouse networks in Hong Kong and mainland China.

2 investors

SPARK Microsystems develops ultra-wideband (UWB) wireless connectivity technology for applications including Physical AI, XR, audio, gaming, human interface, and IoT devices.

2 investors

Sparrow Quantum develops deterministic photon generation technology, producing quantum photonic chips and integrated systems for quantum computing and interconnect applications.

2 investors

Spectra Plasmonics develops Amplifi ID, a portable spectroscopy-based detection device that identifies substances such as street drugs, pharmaceuticals, and food-processing samples in as little as 60 seconds, including through transparent packaging. The device offers automated analysis and reporting with bulk and trace detection modes, without requiring centralized labs.

2 investors

Spectral Labs builds foundation models with spatial intelligence to design and reason about physical systems for engineering and manufacturing applications.

2 investors

Spectrohm develops radio-wave imaging technology that simultaneously images the interior of objects and identifies their material composition while they move on high-speed conveyors. The system is aimed at automated, high-throughput inspection, combining machine vision with AI to distinguish materials such as different liquids.

2 investors