Deep Tech Startups

Seagate Space provides orbital launch services from mobile offshore maritime platforms, offering an alternative to land-based launch ranges. It serves the aerospace, defense, and space launch industry with patent-pending offshore platform designs aimed at increasing launch cadence and reducing weather and community-related constraints.

2 investors

SecuLetter is a content security company that protects against malware and threats hidden in files and documents, serving public sector, financial, and defense customers. The KOSDAQ-listed cybersecurity firm is expanding its content security category since its 2023 listing.

2 investors

Seequent develops geoscience and geotechnical software, including its Leapfrog 3D geological modelling product, that helps organizations interpret and model the subsurface for sectors such as mining, groundwater, and geothermal energy. Now part of Bentley Systems, the company serves geoscientists and geoengineers worldwide with tools for understanding underground data.

2 investors

AkriVita manufactures 3D-printed microcapillary needles designed to improve precision and reliability in biomedical research, genetic research, biotechnology, and fertility treatments. The company serves biomedical scientists and healthcare professionals conducting research, disease prevention modeling, and therapeutic delivery.

2 investors

Seismic Therapeutic is a clinical-stage biotechnology company that uses machine learning to discover and develop immunology therapies for autoimmune diseases. The company develops a pipeline of biologics derived from its IMPACT platform to control dysregulated adaptive immunity.

2 investors

Seismos provides an AI intelligence layer that converts acoustic signals and sensor measurements into real-time completion decisions for oil and gas well operators. Built on a database of perforation efficiency and uniformity measurements across thousands of wells, its physics-based platform delivers recommendations to optimize field operations and enable autonomous control.

2 investors

Seloxium develops a metal recovery and refining technology (branded "Selectal") used for tailings reprocessing, wastewater treatment, bulk metal recovery, and high-purity refining. It targets recovery of metals such as scandium with an emphasis on higher recovery rates, processing speed, and metal purity.

2 investors

Semarion is an advanced materials engineering company that makes SemaCyte microcarriers — barcoded, microfabricated micro-wells that turn adherent cells into assay-ready reagents compatible with automated 384-well liquid-handling workflows. The platform enables cell multiplexing and cryopreserved assay-ready cell batches to speed up in vitro drug discovery screening for pharma and life-science research teams.

2 investors

Sorrento Therapeutics is a biotechnology and life sciences company that develops therapeutics and technologies through in-house programs, acquisitions, and mergers. Its portfolio spans areas including antibody-drug conjugates, cell therapy, and lymphatic drug delivery systems.

2 investors

Semron develops 3D CapRAM, a semiconductor technology that performs computing inside 3D flash memory by stacking many layers on silicon, aimed at meeting the compute demands of AI workloads.

2 investors

Sensmore builds Machine Assist, a physical AI system that gives drivers of heavy machinery real-time situational awareness and collision warnings for people, other machines, and static objects. It combines 4D radar, physical AI, and RTK GNSS localization in a hardware kit aimed at industrial and mining operations.

2 investors

Sensome develops a microchip-based tissue-sensing technology that embeds bio-impedance sensors into minimally invasive medical devices to give physicians real-time, patient-specific data during procedures. Its lead product, the Clotild Smart Guidewire System, provides real-time blood clot characterization for acute ischemic stroke treatment, with additional applications in lung cancer biopsy and peripheral vascular intervention.

2 investors

Seraphim is a venture capital investor focused on space technology, backing space and deeptech startups from inception to exit through its investment funds, accelerator, and investment trust. It supports ventures in areas such as Earth observation, secure communications, defense, and climate intelligence.

2 investors

Serif Biomedicines develops technology to write DNA in different forms so that DNA can be used as a medicine, aiming to create a new category of genetic medicines to treat and prevent disease.

2 investors

sewts develops robotics automation using Physical AI to handle tasks that are difficult to automate. The company focuses on advanced robotics and automation technology.

2 investors

Si-Ware Systems designs proprietary sensing technologies, including miniaturized mid-infrared spectral sensors and full systems, combining chip design, hardware, software, and AI for material analysis. It sells OEM sensors, evaluation toolkits, and complete instruments to engineering teams and industrial partners, and co-develops custom sensing solutions.

2 investors

Sift is an end-to-end platform for teams building advanced hardware that consolidates sensor and telemetry data into a single system for analysis, anomaly detection, and automated test rule evaluation. It offers sub-second anomaly detection, fault-tree investigation on a shared timeline, audit-ready certification reports, and multiple deployment models with built-in security.

2 investors

Signum Technologies develops computer vision and artificial intelligence solutions to detect environmental and physical threats to health and safety for front-line workers, addressing applications in vital sign monitoring and contagion prediction.

2 investors

Silent Ventures is an early-stage venture capital firm that invests in founders building aerospace, defense, and national security companies. The firm focuses on concept-stage pre-seed and seed investments in the defense technology sector.

2 investors

SMG develops high-precision resonant MEMS inertial and gravity sensors, including accelerometers, gyroscopes, and the GAIA gravity system, spun out from Cambridge University research. Its sensors serve autonomous navigation, aerospace, defence, robotics, and geophysics/subsurface exploration applications.

2 investors

SimpleRose is a high-performance computing optimization company developing Rose, a parallel optimization engine for solving large-scale mixed-integer programming (MIP) problems. It parallelizes the entire solving process—branching, cuts, and heuristics—across CPUs and GPUs to give enterprises faster solve times on larger, more complex optimization problems.

2 investors

SiSaf is an RNA delivery and therapeutics company that uses its proprietary bioabsorbable silicon-based Bio-Courier technology to deliver nucleic acids, avoiding the ultra-cold supply chain of conventional lipid nanoparticles. It is developing a pipeline of RNA therapeutics targeting pancreatic cancer, metastatic cancer, and the rare skeletal disease osteopetrosis ADO2.

2 investors

Site Bionics develops technology to enhance human experience by integrating physical-world tools with technology, allowing users to focus on human interactions. The company operates across multiple domains to improve how people interact with their physical environment.

2 investors

Sixfold develops RNA delivery technology for the biotech industry. The company was founded by an oncologist and plant scientist and focuses on advancing RNA-based therapeutic approaches through proprietary delivery methods.

2 investors