Fundraising Fox
Sigma Genetics
YC W17Seattle, US · 2 employees · 3 known investors
Find your way into Sigma Genetics
Sign up to see every warm intro you have to Sigma Genetics
- Paths you didn't know you had: your email and LinkedIn already hold routes to the Sigma Genetics team. We find them for you
- 2nd- and 3rd-degree connections: the friend-of-a-friend routes that take hours to manually find through your inbox or LinkedIn
- Answers now, not in days: momentum is everything in a raise. Skip asking around whether someone knows someone
Days of research, done the moment you sign in, with every route ranked by how warm it is.
Sigma Genetics makes devices that use magnetic fields to introduce DNA, RNA, and other charged molecules into cells, offering advantages over electroporation including reduced arcing, better scalability, and reduced invasiveness for in vivo applications. The technology targets cell therapies, cancer drug delivery, DNA vaccines, biopharmaceutical manufacturing, and cosmetics.
Founders & leadership· Y Combinator alumni (W17)
KE
Karen EatonCEO2016–2017Founder and CEO of Sigma Genetics. Eaton has a background combining business and scientific expertise in the biomedical field.
MS
Matthew ScholzFounderformerMatthew Scholz has founded multiple biotechnology companies and holds patents in gene therapy, immunology, protein production, and oncology. His background spans genetic engineering, cellular programming, and computer security.
CP
Chris PihlFounderuntil 2025Chris Pihl was previously Co-Founder and Chief Technology Officer at Helion, a fusion energy company.
ZR
Zachary R.FounderHe previously led business development at Altoida and consulted for the life sciences advisory firm Pharmagellan, following five years as a senior associate researcher at the Icahn School of Medicine at Mount Sinai. Since 2025 he has also served as an advisor to OncoSenX.
TP
Trevor PelsCEO2016–2017
Investors · 3
IKJ Capitallisted by IKJ CapitalPalo Alto
How we know: IKJ Capital's portfolio page · Not right? Tell us
Y Combinatorlisted by Y CombinatorSan Francisco · $500K
How we know: the Y Combinator directory · funding news · open dataset · 5k.vc investor directory · Not right? Tell us
Founder mafia
2 people who came through Sigma Genetics went on to found or lead other companies.
Related companies · 8
Probably GeneticProbably Genetic operates a platform for diagnosing genetic diseases, providing comprehensive genetic data and testing to patients and healthcare providers. The company works with patient advocacy groups to connect patients with genetic conditions to diagnostic services and community support.
Anto BiosciencesAnto is an AI research lab developing foundation models for microbial communities to enable precision medicine by computationally modeling how the microbiome affects individual drug response. The company serves pharmaceutical and clinical research by combining AI with genomic and microbiome data.
Macrogenics IncMacroGenics is a clinical-stage biopharmaceutical company developing antibody-based therapies for cancer patients. It advances a pipeline of product candidates using proprietary platforms for antibody-drug conjugates, bispecific checkpoint antibodies, and T-cell engagers.
Ochre BioOchre Bio develops RNA therapeutics and drug discovery platforms targeting liver disease, combining proprietary human liver datasets with AI-driven causal prediction and human tissue validation models. The company aims to address the global shortage of liver transplants by developing new treatment options for liver fibrosis and cirrhosis.
Arpeggio BioArpeggio Bio develops pharmaceutical drugs that target transcription factors using artificial intelligence and RNA-sequencing technology, with lead programs in development for melanoma treatment and rare disease applications.
SigmaSIGMA manufactures water infrastructure products including fittings, restraints, castings, and enclosures for municipal and utility applications.
One CodexOne Codex provides microbiome sequencing data analysis and reporting software for academic labs, biotechnology companies, and clinical laboratories. The platform uses advanced algorithms and a curated database to analyze metagenomic samples with a web-based interface accessible to both bench scientists and computational biologists.
PhigenixPhigenix develops personalized medicine for cancer, including companion diagnostics and targeted therapies for prostate and breast cancer patients. Its work centers on early detection and targeted inhibition of PAX2 and EN2 oncogenes and a cancer vaccine using Human Beta Defensin-1 (DEFB1) mRNA to direct the immune system against cancer cells.
Companies working in the same space as Sigma Genetics.
Legal entities · 1
corporate structureSigma Genetics, Inc.
Frequently asked questions
- What does Sigma Genetics do?
- Sigma Genetics makes devices that use magnetic fields to introduce DNA, RNA, and other charged molecules into cells, offering advantages over electroporation including reduced arcing, better scalability, and reduced invasiveness for in vivo applications. The technology targets cell therapies, cancer drug delivery, DNA vaccines, biopharmaceutical manufacturing, and cosmetics.
- Who founded Sigma Genetics?
- Sigma Genetics was founded by Karen Eaton, Matthew Scholz, Chris Pihl, Zachary R..
- Who are Sigma Genetics's investors?
- Sigma Genetics's investors include IKJ Capital, Invariantes Fund, Y Combinator.
- Where is Sigma Genetics headquartered?
- Sigma Genetics is headquartered in Seattle, US.