Who founded Sigma Genetics?

Sigma Genetics was founded by Karen Eaton, Matthew Scholz, Chris Pihl, Zachary R..

Who are Sigma Genetics's investors?

Sigma Genetics's investors include Invariantes Fund, Y Combinator.

Where is Sigma Genetics headquartered?

Sigma Genetics is headquartered in Seattle, US.

Sigma Genetics

YC W17

Seattle, US · 2 employees · 2 known investors

Find your way into Sigma Genetics

801 people in our graph share verified history with the Sigma Genetics team — schools, employers, funds. One of them is your warm intro.

Akshat Goenkaunlockedknows Matthew Scholz · together at Y Combinator (overlapped)

knows the team · via Intellectual Ventures

×2knows the team · via University of Washington

×3knows the team · via Y Combinator

×5knows the team · via UW Foster School of Business

Sigma Genetics makes devices that use magnetic fields to introduce DNA, RNA, and other charged molecules into cells, offering advantages over electroporation including reduced arcing, better scalability, and reduced invasiveness for in vivo applications. The technology targets cell therapies, cancer drug delivery, DNA vaccines, biopharmaceutical manufacturing, and cosmetics.

Biotech Healthtech GenomicsUnited States of AmericaAmerica / Canada

Founders & leadership· Y Combinator alumni (W17)

Karen Eaton in 𝕏Founder/CEOFounder and CEO of Sigma Genetics. Eaton has a background combining business and scientific expertise in the biomedical field.

Matthew Scholz inFounderMatthew Scholz has founded multiple biotechnology companies and holds patents in gene therapy, immunology, protein production, and oncology. His background spans genetic engineering, cellular programming, and computer security.

Chris Pihl inFounderChris Pihl was previously Co-Founder and Chief Technology Officer at Helion, a fusion energy company.

Zachary R.in 𝕏FounderHe previously led business development at Altoida and consulted for the life sciences advisory firm Pharmagellan, following five years as a senior associate researcher at the Icahn School of Medicine at Mount Sinai. Since 2025 he has also served as an advisor to OncoSenX.

Investors · 2

Invariantes FundGuatemala City

Y CombinatorSan Francisco · $500K

Founder mafia

2 people who came through Sigma Genetics went on to found or lead other companies.

Matthew ScholzFounderFounded Oisin Biotechnologies +2 Chris PihlFounderFounded Helion Energy

Competitors · 4

by search overlap

Macrogenics Inc5 shared keywordsMacroGenics is a clinical-stage biopharmaceutical company developing antibody-based therapies for cancer patients. It advances a pipeline of product candidates using proprietary platforms for antibody-drug conjugates, bispecific checkpoint antibodies, and T-cell engagers.

Sigma4 shared keywordsSIGMA manufactures water infrastructure products including fittings, restraints, castings, and enclosures for municipal and utility applications.

Thumbnail for Seragon Pharmaceuticals4 shared keywordsGenentech is a biotechnology company that develops and manufactures breakthrough medicines in the United States, backed by a $50 billion commitment to U.S. manufacturing and scientific innovation.

Phigenix3 shared keywordsPhigenix develops personalized medicine for cancer, including companion diagnostics and targeted therapies for prostate and breast cancer patients. Its work centers on early detection and targeted inhibition of PAX2 and EN2 oncogenes and a cancer vaccine using Human Beta Defensin-1 (DEFB1) mRNA to direct the immune system against cancer cells.

Companies competing with Sigma Genetics for the same Google search keywords, organic and paid, via search-intersection analysis.

Frequently asked questions

What does Sigma Genetics do?: Sigma Genetics makes devices that use magnetic fields to introduce DNA, RNA, and other charged molecules into cells, offering advantages over electroporation including reduced arcing, better scalability, and reduced invasiveness for in vivo applications. The technology targets cell therapies, cancer drug delivery, DNA vaccines, biopharmaceutical manufacturing, and cosmetics.
Who founded Sigma Genetics?: Sigma Genetics was founded by Karen Eaton, Matthew Scholz, Chris Pihl, Zachary R..
Who are Sigma Genetics's investors?: Sigma Genetics's investors include Invariantes Fund, Y Combinator.
Where is Sigma Genetics headquartered?: Sigma Genetics is headquartered in Seattle, US.