Barbara Weber
InvestorBoard director at Tango Therapeutics
Boston, Massachusetts
Writes $100K – $5M checks · typically $1.5M
Find your path to Barbara
287 people in our graph share verified history with Barbara — schools, employers, funds. One of them is your warm intro.
Patrick EnnisunlockedBarbara: together at Yale University (1985)
×10Barbara: together at Third Rock Ventures
Barbara: together at Dana-Farber Cancer Institute
About
Barbara Weber serves as Chairperson of the Board at Tango Therapeutics, a company she helped establish through Third Rock Ventures in 2015 and led as CEO from September 2017 through January 2026. Under her leadership, Tango grew from six employees to over 150 researchers and drug developers focused on cancer genetics, expanding its pipeline to include vopimetostat, a PRMT5 inhibitor entering pivotal development in pancreatic cancer.
Board director at Tango Therapeutics
Intro paths
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In turn, Barbara can intro founders to Tango Therapeutics's investors below.
Tango Therapeutics's investors · 4
Co-founders at Tango Therapeutics
AH
Alan HuangExecutive Officer
Experience
- Tango TherapeuticsChairperson of the Boardcurrent2026 — presentBoston, Massachusetts, United States
- Tango TherapeuticsPresident and CEO2017 — 2026Cambridge, MA
- ITM Isotope Technologies Munich SEBoard Membercurrent2025 — present
- Sesame TherapeuticsBoard Membercurrent2023 — present
- Parabilis MedicinesBoard Membercurrent2018 — presentCambridge, Massachusetts
- REVOLUTION MedicinesBoard Member2018 — 2025Redwood City, California
- Third Rock VenturesVenture Partner2015 — 2019Boston, MA
- NovartisSVP, Oncology Translational Medicine2009 — 2015Cambridge, MA
- GlaxoSmithKlineVP, Oncology2005 — 2009Greater Philadelphia
- University of PennsylvaniaProfessor of Medicine and Genetics1994 — 2005Philadelphia, PA
- University of MichiganAssistant Professor of Medicine1988 — 1994Ann Arbor, Michigan
- Dana-Farber Cancer InstituteMedical Oncology Fellow1985 — 1988Greater Boston
Skills & more
Clinical Development17Oncology52
From Barbara's professional profile.
Deals · 1
Revolution MedicinesBoard seat
via Third Rock Ventures · filed Jul 2018 · $56.4M raise
Attribution from SEC filings, press coverage, and firm rosters.
Network10
Abbie Celniker
Investor at Third Rock Ventures
Alan Ezekowitz
Investor at Third Rock Ventures
Andrea van Elsas
Investor at Third Rock Ventures
Andrew Warren
Senior Associate at Third Rock Ventures
Beryl Cummings
Senior Associate at Third Rock Ventures
Cary Pfeffer
Investor at Third Rock Ventures
Charles Homcy
Investor at Third Rock Ventures
Christoph Lengauer
CSO at Curie.Bio
Craig Muir
Investor at Third Rock Ventures
David Kaufman
Investor at Third Rock Ventures
Investors connected to Barbara in public investor directories — a warm-intro map.
Frequently asked questions
- Who is Barbara Weber?
- Barbara Weber serves as Chairperson of the Board at Tango Therapeutics, a company she helped establish through Third Rock Ventures in 2015 and led as CEO from September 2017 through January 2026. Under her leadership, Tango grew from six employees to over 150 researchers and drug developers focused on cancer genetics, expanding its pipeline to include vopimetostat, a PRMT5 inhibitor entering pivotal development in pancreatic cancer.
- Where does Barbara Weber work?
- Barbara Weber is Board director at Tango Therapeutics.
- What check size does Barbara Weber write?
- Barbara Weber typically writes checks of $100K – $5M.
- What boards does Barbara Weber sit on?
- Barbara Weber holds tracked board seats at Revolution Medicines.
- Where did Barbara Weber go to school?
- Barbara Weber studied at Yale University (Resident in Internal Medicine); University of Washington - School of Medicine (Doctor of Medicine (M.D.), Medicine); University of Washington (Bachelor's Degree, Chemistry).
Founder mafias
Yale University mafia373
Also came through, then founded or led a company.
Michael SeibelBAFounded SocialCamBen SilbermannB.A.Founded Audiobeta +2Justin KanPhysics and PhilosophyFounded Stash +6Jonathan RothbergDoctor of Philosophy (Ph.D.)Founded Raindance Technologies +4Donald IngberDoctor of Philosophy - PhDFounded Unravel Biosciences +3Kevin RyanBAFounded Transcend Therapeutics +2
+ 366 more
Third Rock Ventures mafia23
Also came through, then founded or led a company.
Christoph LengauerPartnerFounded Celsius Therapeutics +3Reid HuberPartnerFounded MOMA Therapeutics +2Alexis BorisyPartnerFounded Foundation Medicine +2Steve PaulVenture PartnerFounded Voyager Therapeutics, Inc. +1Philip ReillyVenture PartnerFounded Luna Genetics +1Uday KumarEntrepreneur-in-ResidenceFounded Element Science +1
+ 16 more
University of Washington - School of Medicine mafia8
Also came through, then founded or led a company.
Eric LeuthardtCombined Epilepsy and Spine FellowshipFounded Inner Cosmos +3Uri LopatinInternshipFounded Assemblybio +2Julien PhamMDFounded RubiconMDCorey Fish, MDMDFounded Brave CareAndrew J Holman MDRheumatology FellowshipFounded InmedixRoss CentersGenome SciencesFounded Ethos Space Resources
+ 1 more
Same school
Also attended Yale University966
Ann Miura-KoCo-founding Partner at FloodgateDavid SzeAdvisory Partner at GreylockMichael SeibelPartner Emeritus at Y CombinatorBen SilbermannCo-founder of PinterestZheela QaiserInvestor at Index VenturesAnthony PhilippakisInvestor at GV (Google Ventures)
+ 960 more
Also attended University of Washington - School of Medicine14
Uri LopatinInvestor at Khosla VenturesDennis SchmulandInvestor at EPIC VENTURESDoug RossInvestor at DigitalDx VenturesDavid CohnInterim Chief Executive Officer and Chief Medical Officer at Oncology VenturesChing-Ping LinPartner & COO at Orbit StartupsJulien PhamFounder & Managing Partner at 3CC | Third Culture Capital
+ 8 more
Also attended University of Washington469
Andrew ChenGeneral Partner at Andreessen HorowitzArvind JainFounder & CEO of GleanJane MooneyCo-founder & VP, Strategy and Finance at Collaborative RoboticsVictoria TreygerGeneral Partner at Felicis VenturesAndrewAdvisor at Clear VenturesJoe HorsmanInvestor at Madrona Venture Group
+ 463 more
Shared employers
Also worked at Tango Therapeutics3
Also worked at Parabilis Medicines3
Also worked at Third Rock Ventures88
Lisa PurcellInvestor at Third Rock VenturesPaul MeloneInvestor at Third Rock VenturesLee VeneziaInvestor at Third Rock VenturesKevin MunnellyInvestor at Third Rock VenturesAmanda ChanInvestor at Third Rock VenturesJigar RaythathaInvestor at Third Rock Ventures
+ 82 more
Also worked at Novartis201
Rebecca JamesInvestor at Index VenturesScott BillerInvestor at GV (Google Ventures)Freya Svedberg-KeatingInvestor at MedicxiAndrea AmadorCompliance Manager at Inveready Technology Investment GroupAbbie CelnikerInvestor at Third Rock VenturesJesper GromadaInvestor at Third Rock Ventures
+ 195 more