Castle Creek Biosciences
Exton, US · Founded 2018 · Delaware corporation · 25 employees on LinkedIn · 4 known investors
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Castle Creek Biosciences develops re-dosable gene therapies for genetic diseases, with a lead candidate (D-Fi) in registrational clinical trials for dystrophic epidermolysis bullosa.
Founders & leadership




Board

Investors · 4
How we know: Paragon Biosciences LLC's portfolio page · paragonbiosci.com · Not right? Tell us
How we know: Valor Equity Partners's portfolio page · board seat on SEC Form D · funding news · paragonbiosci.com · the VCSheet dataset · Not right? Tell us
How we know: funding news · paragonbiosci.com · Not right? Tell us
How we know: funding news · Not right? Tell us
Reported raises · per SEC filings
Form D private placements$839.8M disclosed across 6 rounds · 2018–2025
▶$75MraisedFeb 2025 · 30 investors · BiotechnologyRule 506(b)
- David BrillDirector
- Matthew CrabtreeDirector
- Jeffrey AroninDirector
- Matthew GantzExecutive Officer, Director
- Patrick MorrisDirector
- Jude SullivanExecutive Officer
- Darien ParhadExecutive Officer
- Antonio GraciasDirector
- Offering amount
- $75M
- Amount sold
- $75M
- Sales commissions
- $2.8M
- Placement agents
- Paragon Health Capital, LLC
- First sale
- Feb 2025
- Incorporated
- Corporation, Delaware
- Federal exemptions
- 06b
▶$112.8MraisedMay 2022 · 54 investors · BiotechnologyRule 506(b)
- Mark GrafDirector
- Matthew J. GantzExecutive Officer, Director
- W. Bradford MiddlekauffExecutive Officer
- Mary SpellmanExecutive Officer
- Jeffrey S. AroninDirector
- Patrick J. MorrisDirector
- Antonio GraciasDirector
- Offering amount
- $112.8M
- Amount sold
- $112.8M
- Sales commissions
- $1.7M
- Placement agents
- Paragon Health Capital, LLC
- First sale
- Apr 2022
- Incorporated
- Corporation, Delaware, 2018
- Federal exemptions
- 06b
▶$11.8MraisedFeb 2022 · 6 investors · BiotechnologyRule 506(b)
- Jeffrey S. AroninDirector
- W. Bradford MiddlekauffExecutive Officer
- Matthew J. GantzExecutive Officer, Director
- Mark GrafDirector
- Patrick J. MorrisDirector
- Antonio GraciasDirector
- Babar GhiasExecutive Officer
- Mary SpellmanExecutive Officer
- Offering amount
- $11.8M
- Amount sold
- $11.8M
- Sales commissions
- $625K
- Placement agents
- Paragon Health Capital, LLC
- First sale
- Jan 2022
- Incorporated
- Corporation, Delaware, 2018
- Federal exemptions
- 06b
▶$25MraisedJul 2021 · 36 investors · BiotechnologyRule 506(b)
- Matthew J. GantzExecutive Officer, Director
- Mary SpellmanExecutive Officer
- Gregory MacMichaelExecutive Officer
- Gregory WujekExecutive Officer
- Antonio GraciasDirector
- W. Bradford MiddlekauffExecutive Officer
- Patrick J. MorrisExecutive Officer, Director
- Jeffrey S. AroninDirector
- Offering amount
- $25M
- Amount sold
- $25M
- Sales commissions
- $625K
- Placement agents
- Paragon Health Capital, LLC
- First sale
- Jun 2021
- Incorporated
- Corporation, Delaware, 2018
- Federal exemptions
- 06b
▶$54.6MraisedJan 2020 · 12 investors · PharmaceuticalsRule 506(b)
- Jeffrey S. AroninDirector
- Gregory WujekExecutive Officer, Director
- Patrick J. MorrisExecutive Officer, Director
- Timothy M. CunniffDirector
- Antonio J. GraciasDirector
- Offering amount
- $54.6M
- Amount sold
- $54.6M
- Minimum investment
- $82.4K
- Sales commissions
- $710K
- Placement agents
- Paragon Health Capital, LLC
- First sale
- Dec 2019
- Incorporated
- Corporation, Delaware, 2018
- Federal exemptions
- 06b
▶$560.5MraisedOct 2018 · 19 investors · PharmaceuticalsRule 506(b)
- Jeffrey AroninDirector
- Michael DerbyExecutive Officer, Director
- Antonio GraciasDirector
- Patrick MorrisExecutive Officer, Director
- Timothy CunniffDirector
- Offering amount
- $560.5M
- Amount sold
- $560.5M
- Sales commissions
- $1.2M
- Placement agents
- Octagon Capital Group, LLC
- First sale
- Oct 2018
- Incorporated
- Corporation, Delaware, 2018
- Federal exemptions
- 06b
Source: SEC EDGAR Form D. Amounts as filed; amended filings shown once at their latest values.
Competitors · 1
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In the news
Frequently asked questions
- What does Castle Creek Biosciences do?
- Castle Creek Biosciences develops re-dosable gene therapies for genetic diseases, with a lead candidate (D-Fi) in registrational clinical trials for dystrophic epidermolysis bullosa.
- Who are Castle Creek Biosciences's investors?
- Castle Creek Biosciences's investors include Paragon Biosciences LLC, Valor Equity Partners, Fidelity Investments, Horizon.
- How much funding has Castle Creek Biosciences raised?
- Castle Creek Biosciences has disclosed $839.8M raised across 6 rounds.
- Where is Castle Creek Biosciences headquartered?
- Castle Creek Biosciences is headquartered in Exton, US.





