Longevity Startups

This article covers the Chapter 11 bankruptcy auction process for Oceanwide Plaza, a $1.2 billion mixed-use development in downtown Los Angeles comprising residential towers, a hotel, and retail space that has remained incomplete since 2018.

4 investors

MitoRx develops first-in-class, targeted small-molecule therapies that restore mitochondrial health to treat people with high-risk, metabolically unhealthy obesity and related cardiometabolic diseases. Its lead asset, MTRX31, aims to rebalance carbohydrate and fat oxidation to deliver fat-specific weight loss while preserving lean mass.

4 investors

Moneta Health provides virtual speech therapy focused on cognitive rehabilitation to treat cognitive impairment and dementia, aiming to improve patients' functional independence and quality of life. It serves patients and healthcare providers as part of post-diagnostic care.

4 investors

Death Clock is a preventive health platform powered by AI that identifies early markers of chronic disease before symptoms appear, helping users take action to prevent illness. The platform serves individuals interested in longevity and health optimization through early detection protocols.

4 investors

Muna Therapeutics is a biotechnology company developing therapeutics, with a focus on drug discovery involving medicinal chemistry.

4 investors

Next Health operates wellness clinics offering IV vitamin therapy, NAD+ drips, peptide therapy, and bioidentical hormone optimization delivered through in-lounge sessions and membership plans. It serves consumers focused on longevity and health optimization, with locations in cities including West Hollywood, Century City, Studio City, New York City, Nashville, and Maui.

4 investors

Nitrase Therapeutics is a clinical-stage biopharmaceutical company using its NITROME platform to develop therapeutics based on nitrases, a class of enzymes it discovered that drive protein nitration. Its lead program is an antibody targeting the pathogenic form of alpha-synuclein in Parkinson's disease, with a pipeline aimed at neurodegenerative, cancer, fibrotic, respiratory, and autoimmune diseases.

4 investors

Prenetics is a health company that operates in genetic testing and precision diagnostics and runs the consumer health supplement brand IM8, sold direct-to-consumer and through Amazon and social commerce channels. The company markets longevity and wellness products globally, including partnerships with athletes and sports organizations.

4 investors

Replay develops gene therapies for patients with rare genetic diseases. It operates in the biotechnology and gene therapy sector.

4 investors

Tenpoint Therapeutics develops treatments for age-related ophthalmic conditions, with an initial focus on presbyopia care for the aging eye. The company works with eye care professionals to advance therapies in the ophthalmology market.

4 investors

TRIMTech Therapeutics is a biotechnology company focused on drug discovery and development, backed by investors including Cambridge Innovation Capital and BGF.

4 investors

Vanqua Bio is a biotechnology company developing molecules intended to become medicines for neurodegenerative disorders, including Parkinson's disease, Alzheimer's disease, and related neurological conditions. It serves patients with these diseases through its drug discovery and development work.

4 investors

VitaDAO is a decentralized autonomous organization that funds and coordinates longevity and aging research using AI agents, decentralized governance, and on-chain funding mechanisms such as IP-NFTs. It backs early-stage research projects and companies working on drug discovery and interventions to extend human healthspan and lifespan.

4 investors

PURMX Therapeutics develops nucleic acid medicines as anti-cancer drugs based on microRNA research and the concept of an "ageing switch" to induce ageing in cancer cells. The Japanese pharmaceutical venture handles drug development functions including non-clinical research, clinical development, CMC, and regulatory affairs.

4 investors

Famitra operates a marketing and consulting service focused on family trusts (civil trusts) in Japan. The company helps individuals and families resolve financial planning issues through trust-related advisory services.

4 investors

Ageless (AGE-LESS) is a Japanese company offering human-resources and staffing services focused mainly on the middle-aged and senior workforce, aiming to help people remain economically active regardless of age. It addresses Japan's aging population and post-retirement employment challenges.

3 investors

Aeon offers preventive whole-body health check-ups in Switzerland that combine whole-body MRI and blood biomarker analysis to detect health risks such as cancer early. It works with licensed radiology practices and medical centers and provides tiered packages including physician consultations and body composition analysis.

3 investors

Animate Biosciences develops peptide therapeutics that target pathological tissue remodeling, using an AI platform trained on multi-omic data from highly regenerative organisms to design novel peptides. The company applies regenerative biology and machine learning to rebuild tissue and organ systems for conditions with limited treatment options.

3 investors

Aperture Therapeutics uses machine learning to mine genomic and clinical datasets for naturally occurring protective gene variants, then designs oligonucleotide therapeutics that mimic those variants to treat neurodegenerative diseases such as ALS and FTD and delay brain aging. It targets shared drivers of both familial and sporadic disease, often related to neuroinflammation.

3 investors

Bevel is a consumer health app that synthesizes a user's health data from wearables to provide actionable insights and help individuals manage their own well-being. It emphasizes data interoperability across devices along with privacy and security for personal health information.

3 investors

Bevimi is a cognitive health innovation company developing products designed to support brain health, cognitive performance, and longevity through scientifically-formulated supplements and interventions.

3 investors

Caedo Oncology develops therapeutic antibodies for cancer treatment, leveraging deep immunology and antibody engineering expertise.

3 investors

Capacity Bio is a biotechnology company developing mitophagy modulators — small molecules, peptides, and nanoparticles that target mitochondrial biology to identify and clear dysfunctional mitochondria. Its pipeline includes a first-in-class mitophagy agonist intended for therapeutic use in aging- and disease-related conditions.

3 investors

care.coach is a digital health platform that serves elderly individuals and their caregivers through integrated technology, focusing on fall prevention, reducing emergency department visits, and addressing social isolation in Medicare and Medicaid populations.

3 investors