Longevity Startups

Junevity is a biotech company developing siRNA therapeutics based on its RESET platform, which uses transcription factor repression to restore healthy gene expression and target age-related diseases. The company applies bioinformatics, machine learning, and cellular aging research to develop treatments for metabolism and aging-related conditions.

1 investor

Karydo TherapeutiX (KarydoTX) develops a "Precision Human Digital-Twins System" (Precision hDTS) that measures molecular, cellular, organ, and inter-organ information in real time to create a live digital twin of the body, predicting future conditions to enable early detection, prevention, and treatment of disease. The company aims to contribute to a society of healthy longevity through this integrated, individually customized system.

1 investor

Klotho Therapeutics uses biotechnology to develop therapeutics that mimic the natural human Klotho protein to address age-related diseases including cognitive decline, kidney failure, diabetes, and cancer. The company targets treatments for conditions associated with aging in elderly and disease populations.

1 investor

Libra Therapeutics develops small molecule therapeutics targeting lysosomal function and autophagy to treat neurodegenerative diseases including ALS, Parkinson's, Alzheimer's, and Huntington's disease. The company's approach aims to restore cellular balance by enhancing the body's natural ability to clear toxic proteins and dysfunctional organelles.

1 investor

LifeCellsNI provides cord blood and stem cell extraction and cryogenic storage services for individuals and families, alongside laboratory rentals with GMP-grade processing for researchers, biotech companies, and clinical trials. It operates a biobanking facility serving Northern Ireland and Ireland.

1 investor

Lifeforce offers a health membership that measures over 50 biomarkers and provides personalized insights, health tracking, and one-on-one clinician support. It serves consumers looking to monitor and improve their long-term health and physical performance.

1 investor

Life AI Biohub provides an infrastructure layer for human health that combines AI, biotech, and human participation, offering access to real-world health trajectory data from over 550,000 people. It connects phenotype, intervention, and outcome data—genetic markers, biomarkers, and lifestyle factors—to identify which interventions work for which patient phenotypes.

1 investor

Lifespan.io publishes news, research roundups, and advocacy content focused on longevity and rejuvenation therapies aimed at extending healthy lifespan. It covers developments across research, treatment, and policy related to aging.

1 investor

LifeX Ventures is a venture capital firm that invests in startups working on carbon and climate, longevity, and health, and advises founders on complex CEO decisions. The team is composed of former scientists turned tech entrepreneurs and operators.

1 investor

LiST provides an AI platform for medical underwriting and longevity risk assessment, enabling insurance and financial services partners to make data-driven decisions through natural language processing and automated pricing.

1 investor

Longevitix is a clinical intelligence platform for preventive and longevity medicine that unifies patient data from labs, wearables, genetics, EHRs, imaging, and clinical notes into evidence-based clinical summaries and personalized care plans. It uses AI organ-system analysis to help physicians identify health risks early, track patient trajectories over time, and generate whitelabeled patient reports that fit into existing clinical workflows.

1 investor

Longevity Health Plan is a Medicare Institutional Special Needs Plan (I-SNP) for adults in long-term care, primarily residents of skilled nursing facilities receiving nursing home level care. It provides coordinated clinical care, on-site diagnostics, medication monitoring, preventive home visits, and dental and vision benefits across more than a dozen U.S. states.</parameter> <parameter name="founders">[]

1 investor

The Longevity Science Foundation is a nonprofit organization that funds fundamental research on healthy aging, awarding grants to academic institutions for longevity studies. It partners with universities and medical societies to support longevity R&D in medicine and biotech.

1 investor

Longevity AI offers Florence AI, a clinical tool that analyzes patient data across cardiovascular, metabolic, cognitive, and immune systems, tracks patient trajectories between visits, and drafts clinical summaries, SOAP notes, and personalized care plans. It is built for clinical teams to deliver proactive, preventive care and can be adapted to each practice's protocols and standards.

1 investor

The Longevity Fund is a venture capital firm founded in 2011 to back founder-led biotech companies developing drugs for longevity and age-related diseases. It has since relaunched as a new fund under the name age1.

1 investor

Longevity World is a wellness hub focused on helping individuals pursue longer, healthier lives through fitness, nutrition, and health innovation.

1 investor

The Longevity Biotechnology Association is a global membership organization representing leaders in geroscience and gerotherapeutics, focused on developing medicines and therapies to prevent and cure age-related health conditions. It brings together companies and research centers working in the longevity field.

1 investor

Lucina Biotherapeutics develops therapeutics to treat aging-related disorders, particularly dry age-related macular degeneration (AMD), by restoring very long-chain polyunsaturated fatty acids (VLC-PUFAs) in tissues through its PUFActive platform. The company employs two approaches: synthetic VLC-PUFA formulations for intravitreal injection and engineered microorganism biofactories for oral delivery.

1 investor

Lumena Pharma is a science-based biomedical company focused on human health and longevity, developing pharmaceuticals, nutraceuticals, and research offerings. It also provides testing services aimed at the home health market.

1 investor

LyGenesis is a clinical-stage cell therapy company that uses a patient's own lymph nodes as bioreactors to grow functioning ectopic organs. Its allogeneic cell therapies target diseases including end stage liver disease, end stage renal disease, Type 1 diabetes, and aging of the thymus.

1 investor

LYMA develops consumer beauty and wellness products including a cold-laser skincare device, serums and creams, and dosed nutraceutical supplements aimed at younger-looking skin, sleep, stress, and longevity.

1 investor

MaavRx is developing a one-time AAV5 gene therapy that delivers the TH and GCH1 genes into putamen neurons so they produce constant levels of L-DOPA, intended as a treatment for patients with advanced Parkinson's disease. The therapy aims to provide lifelong symptom control without the pumps, dyskinesia, and high costs of current continuous L-DOPA infusion.

1 investor

Macomics is a drug discovery company developing therapies that target macrophage activity for diseases with limited or ineffective treatment options. It operates in the biotechnology and therapeutics sector.

1 investor

Groupe Maisons de Famille operates a network of more than 150 residential care facilities for frail elderly residents and patients, providing personalized care and support services. It is present in France, Italy, Spain, and Germany and describes itself as the fifth-largest such operator in Europe.

1 investor