Longevity Startups

NovalGen is a clinical-stage biotechnology company developing multi-specific biologics for oncology, autoimmune, haematological, and metabolic disorders using its proprietary AutoRegulation platform technology.

2 investors

NuSirt Sciences develops therapies that activate the sirtuin pathway by combining established pharmaceuticals and natural products to treat cardiometabolic conditions of aging and overnutrition, including fatty liver disease (MAFLD/MASH), obesity, type 2 diabetes, and hypertension. Its lead drug candidate TRIPLN combines L-leucine, metformin, and sildenafil, and it also markets LEUSIX, a dietary supplement for cardiometabolic health and weight management.

2 investors

Nutrigene produces personalized liquid supplements formulated from a customer's health data and a metabolic assessment, aiming to address nutrition-related health issues. It sells directly to consumers seeking tailored nutrition for specific health goals.

2 investors

Opal HealthCare operates residential aged care communities across Australia, offering permanent care, day and long-term respite, and dementia care, along with wellness centres for rehabilitation and restorative care. It serves older Australians and their families, with a care model centred on personal relationships with residents.

2 investors

Orange Grove Bio is a biotech venture firm that builds and backs cell therapy and immuno-oncology companies, forming subsidiary companies (subcos) such as Ipinovyx and DomainOne Therapeutics. It operates in the biopharmaceutical and life sciences investment space.

2 investors

Pannex Therapeutics develops a novel drug class of proprietary Pannexin 1 (Panx1) channel blockers, targeting disease-relevant pathways shared across neurological disorders and cancer. Its initial programs focus on chronic neuropathic pain and triple-negative breast cancer, with plans to expand into broader neurology and oncology indications.

2 investors

Peak Health offers doctor-led longevity care combining advanced diagnostic testing (labs, biomarkers, DEXA scans, VO2 max) with personalized treatment plans including hormones, peptides, GLP-1s, supplements, nutrition, and fitness, all managed through a single health data platform. It serves consumers seeking proactive aging, hormone optimization, and disease prevention, and also offers infrastructure for clinical practices to launch or expand longevity programs.

2 investors

Phycin develops engineered growth factors designed for higher stability and performance, including a thermostable recombinant basic fibroblast growth factor (bFGF) that remains active for 21+ days at 37°C. Its products target researchers and clinicians working in regenerative medicine, cell culture, and related life science applications.

2 investors

Powerhouse.bio is a biotechnology company that combines experimental biology with applied machine learning. The company works at the intersection of biology and computational science.

2 investors

Predictiv Care uses DNA and genomic analysis to identify genetic predispositions so diseases can be predicted and prevented, with a focus on personalized, preventive health. The company aims to make precision and preventive healthcare affordable and understandable for individuals.

2 investors

Previvor Edge offers a multidisciplinary cancer prevention and early-detection program that combines genetic testing, clinical risk assessment, lifestyle guidance, and screening tools such as multi-cancer tests and full-body MRIs. It serves individuals at elevated cancer risk, including those with a family history, and works with multiple insurance plans as well as self-pay options.

2 investors

Remedium Bio is a biotech company developing gene therapy and biologic treatments for osteoarthritis and other rheumatology and metabolic conditions, drawing on research into cartilage regeneration and the FGF18 protein. Its work targets diseases such as osteoarthritis, arthritis, and diabetes-related metabolic conditions.

2 investors

Resalis Therapeutics develops antisense oligonucleotide therapies targeting microRNA pathways for metabolic disorders. The company is advancing RES-010, a treatment candidate for obesity, fatty liver disease, and related metabolic disorders.

2 investors

RevMed is an advanced regenerative medicine company focused on researching and developing therapeutic solutions in the regenerative medicine field. The company aims to extend human lifespan and improve health outcomes through life-centered innovation.

2 investors

SanegeneBio is a biotech company developing RNA interference (RNAi) genetic medicines for obesity, cardiometabolic, and autoimmune diseases. Its LEAD (Ligand and Enhancer Assisted Delivery) platform enables tissue-specific gene silencing in the liver, adipose tissue, muscle, and immune cells via subcutaneous dosing.

2 investors

SciNeuro develops targeted therapeutics for neurodegenerative and age-related brain diseases by integrating patient genetics, health history, and advanced diagnostic tools. The company collaborates with scientific institutions to create disease-modifying therapies addressing aging populations' neurological challenges.

2 investors

Seen Health operates a PACE-style program combining clinical care, home help, care concierge, and a community center for seniors, with a focus on serving families within specific cultural communities. It provides on-site medical appointments, rehabilitation, activities, and meals, and may be free or low cost for eligible seniors.

2 investors

SENISCA is a University of Exeter biotech developing RNA-based senotherapeutics that target dysregulated RNA splicing to reverse cellular senescence and treat age-related disease. Its work centers on modulating RNA biology to address the molecular mechanisms driving cellular ageing.

2 investors

Seraphina Therapeutics develops food- and nature-based consumer health products, starting with the fatty acid C15:0 (pentadecanoic acid), aimed at replenishing micronutrients and metabolites that decline with age. The company focuses on evidence-based nutritional science for consumer wellness.

2 investors

Sirius Therapeutics is a biopharmaceutical company developing siRNA-based therapeutics, including work in the anti-coagulant therapeutic area. It focuses on drug discovery and clinical development of RNA-based medicines.

2 investors

Solaria develops plant-sourced living synbiotics (probiotic-prebiotic products) marketed as medical foods for inflammatory conditions, starting with Bōndia for bone loss in women with osteopenia and a forthcoming product, Arthrīva, for rheumatoid arthritis. The company builds a library of plant-based microbiome solutions backed by clinical trials and a Harvard Medical School partnership.

2 investors

Suvida Healthcare operates value-based primary care centers focused on serving Hispanic seniors and Medicare patients. The company provides medical care and related health services across markets including Texas and Arizona.

2 investors

Tally Health offers longevity products including epigenetic aging tests (the TallyAge cheek swab), science-formulated supplements, and personalized DNA-based insights for consumers seeking to slow aging. It sells these direct-to-consumer through individual products and a membership that combines testing, monthly supplements, and action plans.

2 investors

Teitur Trophics is a biotech company developing therapies that target the sortilin family of receptors (SorCS-receptor biology) to activate the brain's natural survival pathways and preserve brain function. Its approach aims to address multiple neurodegenerative diseases by protecting brain cells from dying.

2 investors