Longevity Startups

CryoBios is a life-extension organization offering cryopreservation services using glucose-based stabilizers and cryo-capsules. It also uses AI data-mining to create a digital record of a client's life and personality, stored on an implanted cryptographically protected gold wafer, and offers an investment strategy to preserve clients' savings.

1 investor

Cyclarity Therapeutics develops drugs based on cyclodextrin derivatives to treat atherosclerosis by removing arterial plaque, targeting the non-degradable cholesterol that accumulates in arterial wall cells. The company aims to provide a preventive therapy for age-related cardiovascular conditions such as heart attack and stroke.

1 investor

DELiver Therapeutics develops small molecule and peptide therapeutics using high-throughput DNA encoded library (DEL) drug screening to address challenging and previously "undruggable" targets in clinical medicine, with a focus on tyrosine kinase targets. Its R&D facilities are located at K2Bio in Houston.

1 investor

Ponce Aurora (deliverthera.com) develops small molecule kinase inhibitors discovered through DNA-encoded library (DEL) screening, including a multi-kinase inhibitor targeting ABL1-T315I and other tyrosine kinases for patients with Ph+ acute lymphocytic leukemia. The company also develops selective JAK/TYK2 inhibitors as senomorphic therapies to regulate the senescence-associated secretory phenotype (SASP) in aging and age-related diseases.

1 investor

EADERM develops pharmaceuticals and functional products based on protection and control technologies for skin and hair tissue stem cells. Its R&D targets novel treatments for alopecia, pressure ulcers, and rare intractable diseases such as premature aging syndromes.

1 investor

ekei labs offers genome-wide DNA methylation sequencing using a proprietary non-destructive enzymatic method, paired with indication-specific AI/ML models to interpret epigenetic data from blood, cells, tissue, and saliva. It serves drug developers and cell/product manufacturers for target discovery, biomarker development, and quality control, and offers a cell test kit that estimates biological age.

1 investor

Element3 Health offers Grouper, a program that connects older adults through in-person clubs, live and on-demand virtual instructor-led classes, brain-health challenges, and members-only online events to encourage activity, social connection, and healthier living. It targets the aging and wellness market for seniors.

1 investor

Eloxx Pharmaceuticals is a clinical-stage biotech developing exaluren, a ribosome-selective glycoside drug candidate that induces readthrough of premature stop codons caused by nonsense mutations to restore full-length functional proteins. It is investigating the therapy for rare genetically defined kidney diseases, specifically Alport syndrome and ADPKD, in patients with nonsense mutations.

1 investor

Emtora Biosciences is a clinical-stage life science company developing eRapa, a novel formulation of rapamycin, to prevent the onset and recurrence of cancer. Its lead program, Serenta (eRapa), is in a Phase 3 trial evaluating safety and efficacy in patients diagnosed with familial adenomatous polyposis (FAP).

1 investor

Endolipid Therapeutics is a biotech developing SHBG-mimicking peptides aimed at reducing ectopic fat accumulation to treat conditions such as fatty liver disease and NASH, as well as cellulite. Its work spans therapeutic and dermocosmetic applications.

1 investor

Enlivex is a Nasdaq-listed clinical-stage biotech developing Allocetra, a macrophage reprogramming immunotherapy targeting age-related knee osteoarthritis to restore mobility and function in aging populations. The company also runs a treasury strategy anchored in RAIN, a prediction markets protocol on Arbitrum, offering public-market exposure to prediction market infrastructure.

1 investor

Enov.one is a telehealth service offering personalized longevity and hormone optimization care, including bio-identical hormone balancing (for optimization, peri- and post-menopause) and pharmaceutical-grade medications and supplements such as B12, NAD+, and GSH. It uses an online assessment and AI, optionally combined with lab or DNA results, to connect patients with board-certified doctors and address conditions like fatigue, brain fog, mood imbalances, and weight management, serving 48 of 50 US states.

1 investor

Eos incubates, launches, and builds early-stage companies developing therapies and technologies in regenerative medicine, spanning small molecules, cell and gene therapies, engineered biomaterials, and enabling technologies. It works with academic labs and research institutions, particularly the Harvard Stem Cell Institute and Harvard-affiliated research centers, to identify and fund innovations aimed at repairing or regenerating organs, tissues, cells, and genes.

1 investor

Epoch Elder Care provides assisted living and dementia care for seniors in India, operating six residential care homes in Delhi NCR and Pune. Founded in 2012 as a home care provider, it serves families seeking elder and dementia care and is part of Age Care Labs.

1 investor

Eterna Care is a mobile app and telemetry system that monitors seniors' vital signs, using GPS, WiFi, and communication features to support safe, independent living. The health monitoring tool is aimed at elderly individuals and their caregivers, and is currently in beta with an early access list.

1 investor

Etiome develops stage-specific medicines by applying single-cell omics and artificial intelligence to map disease progression and identify disease-modifying targets at early biological inflection points for preemptive intervention. Founded in 2021 out of Flagship Pioneering's Preemptive Health and Medicine initiative, the biotech company focuses on treating or reversing disease before it advances to later stages.

1 investor

Fable Therapeutics is a biotech company using protein engineering to develop biologics targeting the activin receptor type II (ActR2) pathway for obesity and related metabolic diseases. Its pipeline addresses body composition and broader metabolic health rather than weight loss alone, serving patients with obesity and cardiometabolic comorbidities.

1 investor

First Longevity operates a longevity-focused platform, including a daily newsletter covering longevity science, investment, and innovation, and DLT, a data system that tracks longevity companies, signals, and trends.

1 investor

FitnessGenes offers an at-home DNA saliva test (or DNA data upload from providers like 23andMe and Ancestry) that screens 600,000+ genetic variants across eight ageing domains, combined with blood and lifestyle data, to produce personalised longevity, nutrition, supplement, and workout plans. It serves consumers seeking to understand health risks and improve healthspan through 180+ genetic reports and actionable guidance.

1 investor

Five Alarm Bio develops pharmaceutical compounds targeting a novel aging mechanism to prevent and treat age-related chronic diseases. The company uses chemical synthesis and screening, along with cellular and animal models, to identify small molecules that restore cellular defense mechanisms against chemical damage associated with aging.

1 investor

Five Lives offers a brain health app for people over 50 that combines light physical activity and science-backed brain training into a daily routine to support memory and autonomy and reduce dementia risk. The evidence-based programme, focused on five lifestyle pillars (nutrition, sleep, physical activity, mood/social and mental stimulation), is developed with memory centres in the United Kingdom and France.

1 investor

The page references health, wellbeing and performance under the banner "Human 3," alongside expertise in AI/ML, medicinal chemistry/pharmacology, and aging-brain research. Insufficient content on the page to determine a concrete product or service.

1 investor

Founders Health is a doctor-led clinic that combines advanced diagnostics, functional medicine, and regenerative approaches to build personalized health strategies for long-term health, performance, and recovery. It offers coordinated care focused on longevity, cognitive performance, hormonal and metabolic balance, and physical resilience.

1 investor

Foundry BioSciences develops protein language models powered by AI for protein engineering to address aging and longevity. The company serves users, partners, and patients globally through novel protein sequences.

1 investor