Longevity Startups

23andMe operates a research platform that collects genetic data from millions of users to advance genomic research and health discovery. The company enables individuals to learn about their genetic traits while contributing to medical research studies that benefit public health.

19 investors

Loyal develops longevity drugs for dogs, targeting the biological processes of aging to extend healthy lifespan and reduce age-associated disease. Its lead drug candidate, LOY-002, is a once-daily pill for senior dogs that addresses metabolic dysfunction and is progressing through FDA conditional approval, alongside a broader portfolio of aging therapeutics and educational resources for veterinarians.

18 investors

NewLimit develops epigenetic reprogramming medicines to extend healthspan and treat age-related diseases at the intersection of computer science and biotechnology. The company builds therapeutic programs that aim to engineer cell identity and reprogram cell age for human patients.

15 investors

BIOAGE develops therapies targeting the molecular pathways that drive aging to increase healthspan and address age-related chronic diseases. The company uses data-driven approaches and bioinformatics to identify and develop its pipeline of aging-focused therapeutics.

12 investors

Tembo Health provides care coordination and management services for seniors, particularly those with chronic conditions and dementia. The platform aims to simplify the healthcare journey for older adults by improving access to physicians and streamlining chronic disease management.

12 investors

Aspect Biosystems develops bioprinted tissue therapeutics using a platform that combines AI-powered bioprinting, computational design tools, therapeutic cells, and biomaterials to create implantable allogeneic tissues. Its pipeline targets metabolic and endocrine diseases, and it partners with pharma and biotech companies to advance cell therapies to the clinic.

11 investors

Juvena Therapeutics develops biologics derived from human secreted proteins to treat aging-related diseases, using AI-enabled drug discovery to identify tissue-restorative therapeutics for muscle and metabolic disorders.

11 investors

Alumis is a clinical-stage biopharmaceutical company developing a late-stage portfolio of targeted therapies for immune-mediated diseases. It focuses on small-molecule drug discovery and development in immunology and inflammation.

10 investors

Arda develops therapeutics using single-cell computational biology to target and eliminate pathogenic cells in chronic diseases. The company combines drug development expertise with cellular biology to create new therapeutic approaches.

10 investors

Cambrian Bio is a clinical-stage drug development company creating precision therapeutics that target metabolic pathways which decline with age, such as AMPK and mTOR. Its lead asset, ATX-304, is an AMPK Network Activator being developed for obesity and prediabetes.

10 investors

Honor Technology develops technology platforms and operates brands that provide goods and services for aging adults, aiming to support independent living. The company works in the aging care and healthtech space.

10 investors

Deciduous Therapeutics develops small molecule and immunomodulatory therapies targeting senescent cells to treat age-related diseases including Type 1 diabetes, autoimmunity, and metabolic disorders. The company serves patients with conditions driven by cellular aging and senescence.

9 investors

Generation Lab offers an at-home epigenetic aging test (SystemAge) that measures 460 biomarkers across 21 organs and systems using DNA methylation, delivering a personalized aging report and action plan for consumers. It uses a needle-free blood collection device and connects users to a network of longevity clinics for follow-up consultations and retesting.

9 investors

Holobiome discovers and develops therapies derived from the human gut microbiome, working to translate microbiome science into probiotics and targeted treatments for whole-body health. The company was founded by research scientists from Northeastern University.

9 investors

Hone is an online clinic offering telehealth consultations, doctor-prescribed medications, and biomarker testing to help aging men and women manage their health. It provides personalized, proactive care aimed at Americans seeking to improve health and longevity.

9 investors

Rosarium Health provides home modification and safety services—clinical assessments by OTs and PTs plus credentialed contractor work—to make homes more accessible for aging and disabled individuals. It operates a national provider network and partners with health plans to reduce total medical expense and improve care outcomes for people receiving home-based care.

9 investors

Rubedo Life Sciences develops therapeutics targeting aging by eliminating senescent cells to extend human healthspan. The company applies artificial intelligence and chemistry to drug discovery in the longevity and regenerative medicine space.

9 investors

Assured Allies provides insurance and health engagement solutions for older adults, partnering with financial institutions to deliver preventive care and protection services. The company serves financial institutions and their policyholders aged 60+.

8 investors

Osteoboost is an FDA-cleared bone health solution designed for postmenopausal women with osteopenia. The company was founded by physicians, engineers, and entrepreneurs to address low bone mass and osteoporosis prevention through clinical innovation.

8 investors

Gordian Biotechnology develops therapies aimed at treating age-related diseases to extend healthy lifespan. It operates in the biotechnology and longevity space.

8 investors

Sage Health provides a connected platform powered by AI that adapts to evolving care and technology requirements.

8 investors

Siphox Health develops early diagnostic testing technology to detect and manage chronic diseases at home, delivered as a painless 5-minute test that enables frequent monitoring. The company targets the U.S. healthcare system to reduce the health and economic burden of chronic disease.

8 investors

Corteria Pharma develops interceptive therapies aimed at treating subpopulations of patients with heart failure, sarcopenia, and obesity. The company operates in the biotech and drug development sector.

7 investors

Everlab is a digital health platform offering personalized preventative medicine and longevity testing across Australia, combining bloodwork diagnostics, genetic testing, and specialist access with an app-based care coordination system guided by longevity-trained doctors.

7 investors