Direct to Consumer Startups

Return Signals operates a two-way iMessage communication platform for DTC ecommerce brands, enabling customer support and personalized sales conversations before and after purchase. The service drives repeat purchases, cross-sells, and retention through AI-powered conversations that integrate with existing commerce and support systems.

1 investor

SIMO makes a daily multivitamin gummy for children ages 3–12 that combines 16 vitamins and minerals with a blend of 11 fruits and vegetables, formulated without added sugars, artificial sweeteners, or common allergens. The product is designed to support immune function, energy levels, cognitive development, and sleep quality through a subscription model with refillable glass bottles.

1 investor

SkinSmart makes FDA-cleared hypochlorous acid (HOCL) skin therapy sprays sold direct to consumers for eczema relief, blemish control, and daily skin hygiene. The antimicrobial products target problem bacteria to support the skin's natural healing process and are suitable for sensitive skin and all ages.

1 investor

SiO Beauty makes reusable medical-grade silicone patches that use compression and occlusion to smooth wrinkles and fine lines and hydrate the skin overnight on areas such as the forehead, eyes, chest, and lips. The products are direct-to-consumer skincare marketed as an alternative to injectables, lasers, and fillers.

1 investor

DrinkSip makes flavored functional beverages, such as a mango-peach drink positioned as a low-guilt option that provides focus. The product is a bottled consumer soft/functional drink.

1 investor

Siren Snacks makes vegan, gluten-free chocolate bark snacks, including flavors such as Dubai pistachio, peppermint, and dark chocolate raspberry sea salt, sold directly to consumers online.

1 investor

SIROBÈ is a skincare brand that makes small-batch products formulated with fruits, flowers, and botanicals, including a men's collection called Vous Doux and everyday essentials like beeswax-based moisturizers. It sells directly to consumers with subscription-based automatic delivery.

1 investor

SISI LAB is a skincare brand offering personalized skin analysis and targeted skincare programs for sensitive skin. The company combines scientific skin analysis with plant-derived beauty products and sustainable practices.

1 investor

Akervall Technologies manufactures premium mouthguards under the SISU brand, using advanced materials and engineering for athlete protection and comfort. The company focuses on sports equipment innovation with emphasis on quality and customer service.

1 investor

Sitka Seafood Market (Sitka Salmon Shares) sells subscription boxes of wild-caught Alaska seafood—including salmon, halibut, cod, rockfish, sablefish, and spot prawns—harvested in season by small-boat fishermen. The seafood is frozen, vacuum-sealed, and shipped directly to consumers' homes.

1 investor

Mercha is an online platform for ordering custom branded merchandise, particularly apparel, for companies to distribute to employees, customers, and sales prospects. The service enables businesses to quickly source and customize promotional merchandise.

1 investor

Skandino designs and sells plant-based bioplastic children's tableware made from pine fiber and sugar cane, developed with therapists to support independent eating and drinking. The products are marketed to parents and caregivers seeking sustainable, ergonomic dishware for young children.

1 investor

Skelt develops vegan, cruelty-free skincare products with dermatologist-tested, clean formulas free of parabens and mineral oil. Its line offers hydrating, protecting, renewing, and brightening products aimed at consumers seeking a minimalist skincare routine.

1 investor

Skida designs and manufactures limited-edition outdoor hats, neck warmers, and headbands with distinctive prints, primarily for winter sports and outdoor enthusiasts. The company produces its original styles in Vermont through local sewists and partners with elite athletes, including as the official headwear supplier for the U.S. Ski & Snowboard Team.

1 investor

Skiezy manufactures patented ski straps designed to securely separate and protect skis during transport and use. The product targets skiers and ski transportation applications.

1 investor

SKIMS designs and sells shapewear, loungewear, and intimates for women. The company operates a direct-to-consumer fashion brand.

1 investor

Skin Institute is a multi-disciplinary medical provider offering skin cancer surveillance, dermatology services, varicose vein treatments, and cosmetic procedures across 12 clinics nationwide in New Zealand. The company serves patients seeking prevention, correction, and enhancement of skin health through evidence-based medical care.

1 investor

Skindays is a curated marketplace connecting consumers with skincare and wellness brands selected for expertise and purpose. The platform offers over sixty carefully chosen brands to help customers make informed skincare purchasing decisions.

1 investor

An online retailer selling skincare products, beauty devices, and related items with HSA/FSA payment options for cost savings.

1 investor

SKINVITY manufactures and sells at-home beauty tech devices for women, including LED light-therapy face masks, anti-cellulite body massagers, and compression/pressotherapy garments paired with clinically tested skincare formulations. The company operates as a direct-to-consumer e-commerce brand focused on the Spanish market.

1 investor

Skio builds a subscription management platform for direct-to-consumer brands, offering tools for customer acquisition, retention, and reactivation. The platform serves ambitious e-commerce and subscription-based businesses looking to scale.

1 investor

Sky Organics develops personal care and beauty products formulated with pure, potent organic and natural ingredients, with over 80% of products carrying USDA Organic Certification or equivalent standards. The company focuses on ingredient transparency, sustainability, and cruelty-free practices for consumers seeking certified natural beauty products.

1 investor

Sleep Strips is an oral dissolvable strip product containing melatonin, GABA, L-Theanine, and 5-HTP designed to help people fall asleep within 10 minutes. The product is marketed as a non-pharmaceutical sleep aid for consumers struggling with sleep onset.

1 investor

SleepyCat manufactures foam and latex mattresses for consumers, offering models with varying firmness levels and specialized features like pinhole ventilation and memory foam technology for improved sleep quality.

1 investor