Digital Health Startups

Life Detection Technologies (LDT) develops a machine-learning platform that monitors core vital signs such as overnight heart rate and respiratory rate to predict COPD exacerbations days before they occur. The system is intended to help clinical care teams intervene earlier, manage rehospitalization risk, and deploy field resources in respiratory care.

2 investors

Life Image (now part of Intelerad, a GE HealthCare company) provides technology that connects physicians and moves medical imaging and data across the patient journey. It serves healthcare providers with interoperability and image-exchange solutions.

2 investors

LifeDNA offers direct-to-consumer DNA testing and analysis focused on methylation and wellness, delivering personalized reports on nutrition, fitness, supplementation, sleep, skincare, and other traits. Customers can order a cheek-swab kit or upload raw data from other DNA services to receive genetic insights and tailored wellness recommendations.

2 investors

LifeMD operates a direct-to-consumer telehealth platform offering online access to board-certified providers for weight loss (including GLP-1 medications like Wegovy and Zepbound), men's and women's health, hormone therapy, mental health, cardiology, and urgent care with same-day prescriptions and lab orders. The service is available to patients across the United States through video and message-based virtual visits.

2 investors

LifeSite provides data protection and asset tokenization products, including secure vaulting for PII, financial, and health records, and a TokenX platform for tokenizing real-world assets on blockchain. It serves businesses and families with compliance-focused data storage, wellness/vaccination tracking, and API tools for building custom solutions.

2 investors

LifeStance provides mental health care through a network of supported psychiatrists, psychologists, and licensed therapists offering in-person and telehealth appointments for conditions such as depression, anxiety, personality disorders, and ADHD. It operates more than 550 centers across 33 U.S. states and accepts major insurance plans.

2 investors

LifestyleRx provides digital health programs for type 2 diabetes and metabolic diseases, delivered by teams of physicians, dietitians, and other healthcare professionals. The platform serves patients in Canada with conditions including prediabetes, hypertension, high cholesterol, heart disease, and related metabolic conditions.

2 investors

Light Touch Technology develops a non-invasive blood glucose sensor using advanced laser technology, eliminating the need for blood sampling in diabetes monitoring. The company, a spin-out venture from Japan's National Institutes for Quantum Science and Technology, aims to commercialize the sensor as home medical devices and wearables.

2 investors

Limber provides a digital health platform for physical and occupational therapy organizations, offering remote therapeutic monitoring, home exercise programs, patient outcome tracking, and CMS compliance tools to improve patient engagement and clinical outcomes.

2 investors

Limber is an AI-powered fitness app that uses motion-sensing wearable technology and neuroscience to enhance adaptive intelligence and help users maintain effortless movement through personalized 10-minute daily training sessions.

2 investors

LinusBio is a precision medicine platform company that uses temporal exposomic sequencing of hair to identify molecular biomarkers for earlier diagnosis, patient monitoring, and drug development. Its diagnostic aid ClearStrand-ASD detects a biomarker associated with autism spectrum disorder, and its pipeline targets other central nervous system disorders such as ALS, ADHD, and schizophrenia.

2 investors

Local Infusion operates modern infusion therapy centers with private suites and an AI-driven platform that coordinates care and manages prior authorizations for patients and referring physicians. It treats conditions such as Crohn's disease, multiple sclerosis, rheumatoid arthritis, and psoriasis, pairing patients with dedicated Infusion Guides and offering transparent pricing.

2 investors

LookDeep Health builds an AI-powered virtual care platform, using computer vision to support hospital workflows such as virtual sitting, virtual nursing, and ambient clinical monitoring. It sells to hospitals and health systems, aiming to help clinical teams monitor and care for patients continuously.

2 investors

Lotus.ai is building healthcare technology serving patients and clinicians. The company combines AI engineering with clinical expertise to develop fast and accessible care solutions.

2 investors

Lucerna Dynamics provides software that identifies injection errors in nuclear medicine procedures, evaluates their impact, and helps reduce error frequency for healthcare teams.

2 investors

LUCID develops patented AI technology that transforms music into measurable health outcomes for focus, recovery, sleep, and clinical applications, serving both consumer wellness users and healthcare providers.

2 investors

Lucidact provides nurse-led remote patient monitoring and virtual care for Medicare and Medicaid patients with chronic conditions such as hypertension, heart disease, and diabetes. Its platform supports member enrollment, clinical data monitoring, medication management, care coordination, SDOH screening, and billing for healthcare providers and organizations.

2 investors

Lulo builds a mobile app that helps families access and redeem Supplemental Nutrition Program (WIC) benefits more easily, increasing redemption rates and reducing time spent on WIC shopping. The platform serves low-income families and aims to address food insecurity by unlocking billions in unused government benefits.

2 investors

Lumeris uses AI combined with human-centered design to address the U.S. primary care shortage, co-creating an AI tool called Tom with physicians and patients to deliver Primary Care as a Service. The company keeps patients and clinicians connected through AI-powered care support.

2 investors

Lumia builds smart earring wearables (Lumia 2) that continuously track over 20 health metrics — including blood flow, sleep stages, readiness, hormonal cycle, and activity — via sensors placed in the ear, paired with a companion app. The consumer device is designed to look like jewelry and targets individuals tracking their health, energy, recovery, and cycle patterns.

2 investors

Luminate Health provides a patient and provider engagement platform for clinical, anatomic pathology, specialty, and hospital labs, giving patients the ability to access, manage, and understand their lab results over time. The platform also supports direct-to-consumer testing, provider portals, and regulatory compliance (such as the ONC Cures Act) for labs across the United States.

2 investors

LumiraDx develops rapid point-of-care diagnostic tests run on its microfluidic immunofluorescence platform, including a SARS-CoV-2 antigen test that detects the virus from nasal and nasopharyngeal swab samples in about 12 minutes. The tests are intended for near-patient use by healthcare providers to aid in diagnosing COVID-19 infection.

2 investors

Lumos provides evaluation and data services—including supervised fine-tuning pairs, human and AI feedback, preference ranking, and reinforcement learning—to improve the accuracy and safety of AI models for health and life sciences. It works with foundational AI labs, startups, and governments, and its team has delivered projects for OpenAI, Google, and Meta.

2 investors

Luna Family Autism provides fully virtual, parent-led ABA (Applied Behavior Analysis) therapy for families of children with autism, with programs designed and directed by Master's and PhD-level Board Certified Behavior Analysts. The service is delivered via telehealth to families in several U.S. states, focusing on flexible, family-centered care with reduced weekly time commitment.

2 investors