Deep Tech Startups
5,885 companies tagged Deep Tech, with their investors and founders.
Silveray develops Digital X-ray Film (DXF®), a flexible detector under 1 mm thick that wraps around pipes and complex shapes to deliver digital radiography where rigid detectors cannot fit. It serves industrial non-destructive testing across oil & gas, nuclear and energy, aerospace, and shipbuilding.
3 investors
SiMa.ai designs silicon and software to enable machine learning inference at the edge, deployed in industrial, automotive, and autonomous systems rather than cloud environments. The company serves manufacturers, vehicle makers, and equipment operators requiring low-latency AI processing on physical machines.
3 investors
Siren Optics builds material analysis systems that use cold atmospheric plasma and AI to perform real-time, non-destructive inspection of materials such as wafers, films, coatings, and battery components. Its PlasmaSens products range from benchtop units to robot-arm and inline systems for quality control in semiconductor, packaging, glass, aerospace, and battery manufacturing.
3 investors
SiriusXT builds the SXT-100, a laboratory-scale soft X-ray microscope that produces label-free 3D subcellular tomograms of whole cells and tissue for disease and drug research. It serves life science imaging labs and biomedical researchers working on infection, cancer, neurodegeneration, and nanomedicine.
3 investors
Sirrus develops chemical building blocks based on patented methylene malonate monomers and oligomeric crosslinkers that polymerize anionically at ambient temperatures. Its technology targets high-performance coatings, adhesives, sealants, binders and other polymer products for chemical industry partners.
3 investors
SiTime develops silicon-based (MEMS) precision timing solutions as an alternative to traditional quartz timing components, with devices used across more than 400 applications. It operates in the semiconductor and timing hardware industry.
3 investors
Sitryx is a biotechnology company, founded in 2018, developing therapeutics with a focus on immunometabolism. It has entered a global licensing and research collaboration with Eli Lilly and Company.
3 investors
Skynopy operates an end-to-end ground station service that connects satellites to the cloud, using a hybrid network of timeshared antennas and its own proprietary ground stations orchestrated through a platform with virtualized modem technology. It serves satellite operators, offering higher data rates, reduced latency, and a single API for accessing ground networks.
3 investors
SMART Photonics is a foundry for photonic integrated circuits (PICs), manufacturing light-based microchips used in data and telecommunications, sensing applications such as Lidar, and medical diagnostics. It offers Multi-Project Wafer services for customers developing integrated photonics products.
3 investors
SOLA Biosciences develops gene therapies for conformational diseases, using its JUMP70 platform to activate the body's protein-folding machinery to refold or remove misfolded proteins. Its lead candidate SOL-257 is a single-dose gene therapy targeting toxic TDP-43 protein aggregates in ALS.
3 investors
Cellular Intelligence is a cell therapy company developing engineered cell treatments for diseases, including a Phase 2-ready therapy for Parkinson's disease acquired from Novo Nordisk. The company applies computational biology and synthetic biology approaches to reprogram cellular function.
3 investors
Sorex Sensors develops sensors based on film bulk acoustic resonator (FBAR) technology for indoor air quality monitoring, detecting toxic particulates and volatile organic compounds in the sub-PM2.5 range. The sensors are thin, with high mass sensitivity down to femtograms.
3 investors
Soufflé Therapeutics develops nucleic acid medicines that precisely target and deliver genetic therapeutics to specific cell types to treat disease. The company focuses on creating potent, precise medicines for patients across various disease areas through advanced delivery platforms.
3 investors
Soul Machines develops "Experiential AI" technology to create lifelike, human-like Digital Workers that can see, hear, react, remember and respond emotionally, using cognitive modeling and a patented Digital Brain. Its Digital Workforce product orchestrates across AI systems such as LLMs, autonomous agents, workflows and private data sources to deliver personalized interactions for businesses.
3 investors
Space Kinetic develops the Whirlwind platform, a system that deploys micro-payloads from a host spacecraft at high velocities without using a thruster by decoupling propulsion from the payload. The technology targets space missions with a scalable "one-to-many" architecture aimed at lower unit costs.
3 investors
SpaceComputer is a distributed satellite network providing censorship-resistant computation and verifiable settlement across Earth and orbit, using satellite-hosted trusted execution environments (TEEs), confidential smart contracts, and quantum-hardened cryptography. It offers space-based confidential compute infrastructure with developer-friendly APIs for integrating security services into enterprise solutions.
3 investors
Spaceium builds in-orbit refueling stations that store fuel and supply it to spacecraft, aiming to enable longer missions, larger payloads, and farther travel. The company operates in the space infrastructure sector.
3 investors
SpaceKnow offers Guardian, a platform that integrates data from multiple satellite providers and applies AI algorithms to extract insights from raw imagery. It provides automated change detection, continuous surveillance, and alerts to support monitoring and data-driven decisions.
3 investors
SparingVision is a genomic medicine company developing gene therapies for ophthalmic diseases, including SPVN06, a neuroprotective gene therapy for retinal conditions. Its lead candidate is being evaluated in the PRODYGY clinical trial.
3 investors
SpectraWAVE develops optical and computational imaging technologies to diagnose and guide treatment decisions for patients with coronary artery disease and cardiovascular disease. The company operates vertically integrated design, manufacturing, and commercialization operations for its medical devices.
3 investors
Sphere Semi uses an AI engine to design, validate, and fabricate analog chips, starting with RF components and mixed-signal blocks. It delivers custom chips and reusable IP such as LNAs, PAs, filters, SerDes, and ADCs/DACs built to customer specifications.
3 investors
Spiderwort Biotechnologies is a biotechnology company developing natural, science-based solutions with potential applications across multiple industries.
3 investors
SpinDrive designs, supplies and supports active magnetic bearing (AMB) systems and controller platforms for industrial OEMs whose high-speed machinery depends on bearing performance and lifecycle cost. It offers complete AMB systems, controllers (Magma X100 and X800), and services including feasibility studies, system design, retrofits, condition monitoring and lifecycle support.
3 investors
Spiritus develops direct air capture (DAC) technology to remove carbon dioxide from the atmosphere and sequester it, providing a scalable and modular system for carbon dioxide removal at lower cost.
3 investors