Deep Tech Startups

Principle Power provides technology and engineering services for floating offshore wind turbines, enabling wind farms to be deployed in deep water and challenging seabed conditions worldwide. The company develops and commercializes its patented WindFloat product portfolio for developers, utilities, and power producers pursuing renewable energy generation.

1 investor

Prior Computers is an AI research company developing systems intended to have human-like intelligence, drawing on deep learning and cognitive science. It is hiring people with technical backgrounds to work on machine intelligence.

1 investor

Priori Analytica develops Boethius, a causal intelligence platform with layered architecture for data ingestion, machine learning, decision recommendations, and edge deployment. The platform serves operators and organizations requiring explainable AI-driven insights across contested or data-constrained environments.

1 investor

Priortech is a company creator and investor focused on the global semiconductor industry, developing solutions through two industry-leading businesses, Camtek and ACCESS.

1 investor

Prismlab is a 3D printing company specializing in photocurable (SMS) 3D printing equipment and materials, serving industries including dental applications. The company develops and produces industrial-grade 3D printers, photosensitive resin materials, and software for digital dentistry workflows.

1 investor

Prism ML develops compact large language models that run locally on consumer devices; its Bonsai 27B model supports multi-step reasoning, tool calling, agentic workflows, and multimodal understanding on phones and laptops. The models come in 1-bit (3.9GB, phone-capable) and Ternary (5.9GB, laptop-optimized) variants.

1 investor

Zepp.solutions develops hydrogen fuel cell systems for heavy transport and mobile applications, enabling zero-emission operation without compromises to range or usability. The company provides a sustainable diesel alternative for trucks, construction equipment, and maritime applications.

1 investor

PrivateCore provides software for remote server integrity attestation and data protection in cloud environments. The platform enables enterprises and cloud service providers to verify server integrity and execute applications securely on remote infrastructure using cryptographic and virtualization techniques.

1 investor

PRIVUS develops post-quantum encrypted communications and surveillance detection technology for privacy-conscious individuals and organizations. The platform provides military-grade end-to-end encrypted messaging, voice, video, and file sharing, along with a hardware device that detects IMSI catchers and operates as a secure 4G hotspot.

1 investor

Promatix develops bispecific antibody drug conjugates (ADCs) for solid tumours, using a proteomics-based platform to identify cancer surface marker pairs for cis-bispecific targeting. It is building a pipeline of cancer therapies with a lead program in colorectal cancer.

1 investor

Procarta Biosystems develops gene control technology to treat drug-resistant bacterial infections, including MRSA. The company was spun out from the John Innes Centre and Plant Biosciences Limited and focuses on anti-infective therapeutics for the biotech and pharmaceutical sector.

1 investor

Procavea Biotech develops a protein-based molecular delivery platform (nonviral protein cages) to address delivery limitations in RNA therapeutics, with applications also in medical imaging. An ETH Zurich spin-off, it targets the pharmaceutical and biotech sector.

1 investor

Process Vision develops optical measurement and imaging technology for the oil and gas industry, focused on improving process efficiency, reducing maintenance costs, and lowering emissions. The company serves operators and producers in the energy sector with advanced analytical instrumentation.

1 investor

ProDigest operates advanced in vitro gut simulation platforms that help companies across industries develop superior products. The company specializes in microbial fermentation and gut microbiome research technologies.

1 investor

Prodigy Research is an AI research lab building a foundation model for quantitative trading, and operates live trading systems in financial markets. It targets the trading and financial-reasoning domain, applying proprietary AI models and agents to equities and delta-neutral strategies.

1 investor

Product Genius is an AI/ML company applying deep learning and language model technology to its products. The about page focuses on the founder's background but provides limited detail on the specific product or target customer.

1 investor

Profundus develops an ophthalmic retinal camera that uses Multi Conjugate Adaptive Optics (MCAO) with multiple deformable mirrors to capture high-resolution, wide-field images of the retina. The device resolves retinal features down to a few microns and offers higher resolution and a larger field of view than conventional fundus cameras and single-conjugate adaptive optics systems.</parameter> <parameter name="founders">[]

1 investor

ProHawk AI develops computer vision software that restores video and image quality in real-time across challenging environmental conditions—rain, snow, sand, night, glare—to enable reliable automation and AI systems for safety, security, and forensics applications.

1 investor

Wyss Zurich is a translational accelerator embedded within ETH Zurich and the University of Zurich, providing funding, infrastructure, technology platforms, and entrepreneurial support to early-stage projects. It focuses on regenerative medicine, robotics, and medical devices/bionics, helping move academic research toward clinical and commercial application.

1 investor

Lumos is building a foundation model of human physiology that learns from raw physiological signals to improve medical diagnosis and drug development. The company trains multimodal, continuous-time models on full-resolution physiological data streams to unlock insights that current medicine discards.

1 investor

ProJenX is a clinical-stage biotechnology company developing novel, brain-penetrant therapies for neurodegenerative diseases, with an initial focus on amyotrophic lateral sclerosis (ALS). The company was created through a collaboration between nonprofit Project ALS, Medical Excellence Capital, and researchers at Columbia University to develop and commercialize therapeutic candidates including prosetin.

1 investor

Promega provides a portfolio of reporter bioassays used to characterize and develop monoclonal antibody and cell-based therapeutics for drug developers. The assays measure biological functions including Fc effector activity, immune checkpoint modulation, T cell activation, and cytokine signaling.

1 investor

Promethean Particles manufactures metal-organic frameworks (MOFs) using proprietary continuous-flow production technology for industrial applications including carbon capture, gas storage and separation, and atmospheric water harvesting. The company, a spin-out from the University of Nottingham founded in 2007, operates the world's largest MOF manufacturing plant and partners with research institutions and engineering companies to scale MOF solutions.

1 investor

Prometheus UM is a modular and scalable electrochemical reactor system that uses electrodes, actuators, and fluid handling devices to conduct reactions activated by saline solution and readily available materials. The system monitors operational parameters in real time and is designed for industrial applications across various scales.

1 investor