Deep Tech Startups

Promin Aerospace develops small orbital launch vehicles using proprietary gasification technology to eliminate space debris by consuming rocket engine tanks during flight. The company targets pico and nano satellite deployment with rapid launch timelines.

1 investor

ProMIS Neurosciences is a clinical-stage biotechnology company developing antibody therapeutics that target toxic misfolded proteins in neurodegenerative diseases such as Alzheimer's, ALS, and Parkinson's. The company operates in the biotechnology and neurology therapeutics space.

1 investor

ProSeed designs and manufactures microwave-based drying and separation systems that apply electromagnetic energy directly to moisture or solvents within products at industrial scale. The company serves pharmaceutical, minerals, and food processing industries with fully electric, material-specific processes.

1 investor

PROSION Therapeutics develops platform technology for oncology and other diseases based on research into protein targets like Ena/VASP; the company translates academic research into clinical treatments for conditions with significant patient impact.

1 investor

ProteomEdge develops mass spectrometry-based analytical platforms and proprietary heavy-labelled protein standard panels for absolute protein quantification in blood plasma, targeting clinically relevant biomarkers such as apolipoproteins, complement factors, and liver disease markers. Its products serve research and translational proteomics customers, including academic core facilities and precision medicine researchers. Based in Stockholm, Sweden.

1 investor

Proteros provides structural biology, cryo-EM, protein sciences, and biophysics research services for drug discovery and development. The company operates cutting-edge laboratory facilities in the Munich biotech cluster in Germany.

1 investor

Proto-Town describes an initiative to create a new place with frontier-oriented infrastructure intended to support fast building, experimentation, and reindustrialization. The page is a manifesto-style statement about restoring a culture of invention rather than a concrete product description.

1 investor

Protogon Research designs and deploys autonomous AI systems directly into financial markets through proprietary trading operations. The company leverages machine learning and real market feedback to develop and continuously improve intelligent trading systems.

1 investor

ProTransit is developing Pro-MP, a patented sustained-release microparticle drug delivery platform that penetrates skin, scalp, eye, and mucosal tissues (and can be IV-administered) to deliver pharmaceutical active ingredients locally with minimal systemic uptake. Based on research from the University of Nebraska Medical Center, Creighton University, and USC Keck School of Medicine, the technology targets applications such as skin health and hair regrowth.

1 investor

Provenant builds open infrastructure for verifiable digital communications and branded calling, using cryptographic proof (vLEI, KERI, ACDC) to authenticate calls and messages and support fraud detection and regulatory compliance. Its Origin API platform serves telecommunications operators, enterprises, and sectors such as healthcare, financial services, government, and supply chain.

1 investor

Proxima Technology develops AI products using mathematical algorithms—including machine learning, optimization, control theory, and 3D data analysis—primarily for manufacturing and industrial sectors to improve business operations.

1 investor

Proxisense develops high-performance sensors for monitoring manufacturing processes and diagnostics, with origins in aerospace and defence applications. The company commercializes sensor technologies initially developed for jet engines and oil monitoring.

1 investor

PS Audio Design develops audio and haptic surface technology that enables devices to produce sound and tactile feedback directly from their surfaces. The company serves device manufacturers seeking to enhance user experience through improved audio and haptic capabilities.

1 investor

Psigryph develops Nanopect, a patented plant-derived nanodelivery system that transports bioactive molecules (nutrients, cannabinoids, pharmaceuticals) across cell membranes of plants, animals, and humans to increase bioavailability. The technology, derived from Montmorency sour cherries, targets industries including food and beverage, agriculture, pharmaceutical, and cannabis.

1 investor

PSYONIC develops advanced prosthetic hands with sensory feedback capabilities designed to be affordable and accessible globally, particularly for people with limb differences in underresourced regions. The company combines engineering expertise with clinical partnerships to advance bionic technology at scale.

1 investor

PTX provides engineering services and strategic materials technology to U.S. Federal customers in the aerospace and energy sectors, drawing on experience across commercial and Federal projects. It offers technical and project management capabilities for critical missions and national assets.

1 investor

Pulmatrix develops inhaled dry-powder therapies using its proprietary iSPERSE technology, which uses small, dense, dispersible particles to deliver respiratory and non-respiratory drugs via the respiratory system. The company pursues its own drug pipeline and partnerships with pharmaceutical companies across drug classes.

1 investor

Pulse develops a laser-based system to deliver remote, on-demand power to satellites in low Earth orbit, addressing rising power demand from growing satellite deployments. Its product Boost transmits kilowatt-scale power over distances up to 1000km to satellite receivers.

1 investor

Pumpkin VR develops AI-driven guide systems and extended reality simulation training solutions for museums, defense operations, medical education, and industrial safety across government facilities, hospitals, and enterprises. The company offers six solution categories including AI tour narration, XR/VR/MR immersive training, and AI eldercare interaction systems, deployable on cloud, private cloud, on-premise, or fully offline infrastructure.

1 investor

Puralytics manufactures the Shield, an LED-powered water treatment system using proprietary nanotechnology to remove contaminants, emerging pollutants, and pathogens through advanced oxidation. The technology serves industrial water treatment, manufacturing processes, and waste treatment applications.

1 investor

Purple Gaze offers FOXIE, a hardware and software product available under commercial pricing and through a Research Support Program with subsidies for academic researchers. The context suggests an eye-tracking or gaze-measurement product for research and commercial use.

1 investor

PxE develops holographic imaging technology that captures fused RGB, infrared, and depth data from a single snapshot using one lens, sensor, and chip. Its edge-processed vision and perception systems target cost-sensitive and portable platforms across multiple industries, offering high image quality and depth accuracy in all lighting conditions.

1 investor

A company that builds voice technology products, including Spoketack and Tasted, and is developing a new product called Worbler AI, currently in beta.

1 investor

Pyro Fire Extinction is a Spanish technology company that develops solutions for wildfire monitoring, early detection, and risk management in critical environments, including its BseedWATCH platform combining forest sensors and 360° detection cameras and the MAK 5 long-term fire retardant. It serves electric utilities, public administrations, private companies, and local entities.

1 investor