Deep Tech Startups

Prophesee develops event-based (neuromorphic) vision sensors and AI systems that mimic human vision, processing only scene changes to enable high-speed, low-power, high-dynamic-range machine perception. Its technology serves security, defense, aerospace, industrial automation, and mobility applications, including drone detection and industrial vision systems.

7 investors

Quantum Brilliance designs and manufactures diamond-based quantum chips and products that operate at room temperature, targeting deployment across data centers, edge computing, and field applications. The company provides compact, robust quantum devices integrated with existing sensing and computing infrastructure.

7 investors

Quantum Circuits develops superconducting quantum computers using dual-rail qubits with built-in error detection, designed to accelerate the path to fault-tolerant quantum computing. The company targets enterprises and institutions seeking reliable, scalable quantum computing solutions.

7 investors

Robust.AI develops AI and robotics technology with a focus on human-centered design. The company builds expertise in artificial intelligence, robotics systems, and human-robot interaction.

7 investors

Senti Bio develops cell and gene therapies for cancer and difficult-to-treat diseases using synthetic biology and engineered Gene Circuits to enhance precision, control, and selectivity in targeting tumor cells. The company is a clinical-stage biotech firm leveraging proprietary platform technology across multiple cell types and modalities.

7 investors

Skyloom builds space-based optical communication systems that provide high-capacity data relay between satellites and from satellites to Earth in low Earth orbit. It serves businesses and governments operating satellite constellations for observation and communication applications, engineering its services in-house.

7 investors

Softmax builds AI systems based on organic alignment principles—the concept that agents remaining aligned with human values also maintain alignment with each other. The team conducts research spanning AI safety, multi-agent frameworks, and governance methods.

7 investors

Space BD provides end-to-end support for space business, including satellite development and manufacturing, launch and deployment, on-orbit demonstration, and ground transport support. It also supports microgravity utilization for life science and materials R&D, and runs space-focused education and human-resource development programs for students and companies.

7 investors

Syenta develops high-resolution interconnect technology for chip-to-chip connections using Localized Electrochemical Manufacturing, enabling higher bandwidth between compute and memory in AI systems. The company targets semiconductor and AI hardware manufacturers with a manufacturing process designed for large-scale packaging.

7 investors

Tensordyne builds AI hardware, chips, and software systems optimized for efficient inference at reduced energy and computational cost. The company serves organizations seeking advanced AI capabilities with simplified deployment and lower operational overhead.

7 investors

Transmutex develops accelerator-powered technology that converts nuclear waste into clean energy and produces medical radioisotopes. The company serves energy providers, waste management operators, and healthcare providers across the nuclear energy, waste management, and medical sectors.

7 investors

Using few-shot learning to design better drug candidates, faster

7 investors

VEIR manufactures low- and medium-voltage superconducting systems that deliver electricity for high-performance AI data centers. The company serves hyperscalers, chip developers, and data center operators seeking increased power density and reliability.

7 investors

CesiumAstro develops AI-enhanced, software-defined communications systems for space, air, and ground domain applications. The company provides advanced communication capabilities to mission-critical users across multiple operational environments.

7 investors

Windborne Systems collects atmospheric data using long-duration balloons and applies AI models to produce weather forecasts for business applications. The company operates in weather intelligence and meteorological data services.

7 investors

Xcimer is a laser fusion energy company developing a low-cost, high-energy excimer laser architecture. Its Phoenix system, in Denver, is an electron-beam-pumped excimer laser that demonstrates long-pulse operation and Stimulated Brillouin Scattering pulse compression to validate its fusion energy approach.

7 investors

Zapata Quantum is a publicly traded company (OTCQB: ZPTA) that develops quantum algorithms and applies agentic AI to automate quantum resource estimation workflows. Its work targets quantum chemistry applications, including drug discovery, energy, and advanced materials development.

7 investors

ElevationSpace develops small-satellite re-entry and recovery technology to return the results of in-orbit experiments to Earth, aiming to build an orbital transport network for people and goods. Based in Japan, it is developing "Aoba," described as Japan's first private-led re-entry satellite, carrying experiment payloads for companies such as Euglena.

7 investors

Aerska develops RNA interference (RNAi) medicines designed for targeted delivery across the blood-brain barrier to treat, delay, and prevent central nervous system and neurological diseases. The company combines next-generation RNA therapeutics, brain delivery technologies, and biomarker-guided precision medicine to silence disease-causing genes in the brain.

6 investors

Agile Space Industries manufactures in-space chemical propulsion systems including thrusters and rocket engines for satellite and spacecraft operations. The company serves customers in the space economy with vertically integrated design, manufacturing, and testing capabilities.

6 investors

AIRY3D develops depth-sensing technology, including its DepthIQ system integrated onto CMOS image sensors, to give machines 3D perception. A spin-off of Montreal startup factory TandemLaunch, the company holds over 28 patents and serves customers across multiple industry verticals worldwide.

6 investors

Akselos provides SPM (Structural Predictive Maintenance) technology that models how operational decisions like ramp rates and startup/shutdown procedures affect stress, fatigue accumulation, and brittle fracture risk in refinery reactors. It serves petrochemical and refinery operators aiming to run faster cycles while maintaining structural integrity and uptime.

6 investors

Albert provides an operating system for chemists that combines structured data management with AI trained on molecular structures and individual company chemistry datasets. The platform centralizes lab notebooks, experiments, and projects while enabling AI-driven predictions for formulation optimization and discovery acceleration in materials and chemical R&D.

6 investors

Aliro provides a full-stack software platform for quantum networking, including simulation, orchestration, and operating system solutions that enable enterprises and government agencies to plan and deploy quantum networks for applications like QPU interconnection and quantum-secured communications. The company serves financial services, defense, telecom, and utility customers seeking to operationalize quantum networking infrastructure.

6 investors