AI & Machine Learning Startups

Opal provides an identity governance platform that applies access controls across human users, AI agents, applications, and infrastructure from a single layer. It offers just-in-time privileged access, automated access reviews, and audit logging aimed at enterprises and regulated environments.

4 investors

Opalite builds language interpretation technology for healthcare, enabling real-time communication between physicians and patients across language barriers. The platform serves clinicians and care teams to improve patient safety and diagnostic accuracy.

4 investors

Open builds AI systems for customer communication and support that automate ticket resolution, quality assurance, and customer insights in a single unified platform. The company serves businesses looking to consolidate fragmented customer service operations.

4 investors

Open8 is a Japanese technology company focused on the information and content industry, aiming to turn the vast flow of online information into higher-quality content and serve as an information infrastructure for businesses. It positions itself as a partner for companies in delivering and using rich content.

4 investors

Open Mineral applies data-driven strategies and machine-learning models to trading and financing across global base and critical mineral markets. It offers investment vehicles for accredited and institutional investors, including AI-driven metal derivatives trading, an offtake fund, and a critical minerals trade finance fund.

4 investors

OpenCode is an open-source AI coding agent that assists developers with writing code across terminal, IDE, and desktop environments. It supports multiple LLM providers and prioritizes user privacy by not storing code or context data.

4 investors

OpenHome is a platform for building ambient, voice-based AI devices, providing developers and OEMs with an on-device OS, local models, a sensor layer, voice SDK, and a DevKit. Its SDK handles wakeword, speech-to-text, LLM routing, text-to-speech, and hardware I/O, running privately and locally on the OpenHome DevKit or any Linux-based hardware for applications ranging from medical transcription to smart home integration.

4 investors

OpenInfer builds inference infrastructure and tools that enable AI models to run efficiently on resource-constrained platforms and edge devices. The company serves developers, enterprises, and platforms needing to deploy AI without centralized compute dependencies.

4 investors

OpenLegacy provides an AI-driven platform for incremental modernization of legacy enterprise systems, analyzing dependencies and automating integrations to move critical systems to the cloud without downtime. It serves large enterprises, particularly in banking, insurance, and financial services, across global markets.

4 investors

Opennote is an AI-powered learning platform that consolidates lecture materials, notes, and readings in one place and provides contextual explanations, practice tools, and video tutorials to help students understand course content.

4 investors

OpenReel is a remote video capture and creation platform that lets teams record high-quality (up to 4K) video on any device from any location, with AI-powered editing, branded templates, and secure cloud storage. It serves brands, agencies, and organizations producing marketing, internal communications, and other branded video content, and is part of the Banzai family.

4 investors

Openroll provides a platform that connects to people and finance systems to enable compensation management, workforce planning, and financial analysis. The platform allows HR and finance teams to set salary bands, track headcount and hiring costs, monitor compensation in real time, and answer business questions through AI-powered analysis and automation.

4 investors

OpenSesame provides workforce learning through integrated software, curated and customizable course content, and expert services that embed into an organization's existing learning, HR, and work systems. It uses AI features such as translation, course creation, and coaching to help enterprises train employees at scale.

4 investors

Oper provides AI-powered software for mortgage lenders to automate operational tasks and streamline the loan application process for borrowers. The platform uses agentic AI to handle repetitive decisioning and workflows within European financial institutions.

4 investors

Operata provides a real-time CX Insights Graph that correlates technical, operations, and experience data to surface performance anomalies and actionable recommendations for contact center and customer experience teams. The platform uses AI to automatically detect issues across call quality, agent performance, and network conditions, enabling teams to reduce mean time to resolution and proactively improve customer interactions.

4 investors

Operative Intelligence builds software that analyzes customer interactions across contact center touchpoints to identify the root causes of complexity and give teams tools to act on that information. It serves contact center and customer experience operations.

4 investors

Oplit provides a supply chain planning platform that uses optimization algorithms and agentic AI to continuously recompute production plans in real time across factories. It serves industrial and manufacturing companies in demanding sectors such as aerospace and food production, replacing legacy APS systems and spreadsheets with AI-generated, financially-ranked planning decisions.

4 investors

Opsys develops solid-state scanning LiDAR sensors with no moving parts, using VCSEL and SPAD chip technology for autonomous driving and industrial applications.

4 investors

Opti provides AI-native identity and access management (IAM) software for enterprises, automating privilege management and access decisions through domain-trained machine learning models. The platform integrates with existing directories and applications to enforce least-privilege access and continuous compliance.

4 investors

Optic builds open source tools that help software developers document, review, and version API changes during code review, catching breaking changes before they reach production. The tools apply Git, code review, and CI concepts to API descriptions for engineering teams.

4 investors

Optifino operates an AI-powered digital brokerage general agency (BGA) that connects life insurance agents and advisors to 25+ carriers at once, enabling policy case design, real-time comparisons, and client-ready visualizations in minutes. It serves life insurance agents, financial advisors, and their clients in the life insurance industry.

4 investors

Orakl Oncology, a spin-off from Gustave Roussy, builds an AI-and-biology platform that grows patient-derived tumor organoids and enriches them with genomic, transcriptomic, phenotypic, and clinical data to predict drug response and clinical trial outcomes. It offers O-Predict for anticipating clinical endpoints and biomarkers and O-Target for therapeutic target discovery, serving biopharma companies in oncology drug discovery and development.

4 investors

Orangewood Labs develops physical AI and robotics, including programmable robotic arms, with real-world deployments performing millions of manufacturing tasks. It targets manufacturers and small and medium enterprises.

4 investors

Orbify offers a satellite intelligence platform that monitors vegetation threats, climate risks, and infrastructure changes for energy markets and the environmental sector. Its Earth Observation data helps organizations prevent outages, optimize maintenance, and stay compliant, starting with short pilot deployments on priority corridors.

4 investors