AI & Machine Learning Startups

Orbiit provides a platform for community organizations to identify and facilitate connections between members, from initial introductions through scheduling and feedback collection.

4 investors

Orbio AI provides an AI-powered HR system for enterprise and large workforce organizations, automating recruitment, candidate outreach, and retention management through specialized AI agents that integrate with existing HR tools.

4 investors

Orbit Discovery provides peptide discovery solutions for pharmaceutical and biotechnology companies, serving both large pharmaceutical firms and smaller biotech enterprises.

4 investors

Orbital builds AI purpose-built for real estate legal work, connecting documents, workflows, and decisions to help real estate teams handle complex transactions. It serves real estate professionals and legal teams across the UK and US.

4 investors

Orbital RX provides a software platform for hospital pharmacy supply chain management that integrates inventory tracking, procurement workflows, and real-time team collaboration to coordinate shortage response across healthcare networks.

4 investors

OrCam builds AI-powered handheld and wearable assistive devices, such as the MyEye and Read product lines, that read text aloud, describe surroundings, and recognize faces. The products serve blind, visually impaired, and low-vision users as well as people with reading challenges like dyslexia and ADHD.

4 investors

Orchestra is a platform that unifies scientific, operational, and financial data into a single intelligent environment serving biotech and research teams. It functions as both a system of record and intelligence layer to enable data-driven decision-making and operational alignment.

4 investors

Ordaōs uses AI and deep learning through its Design Engine to design novel mini-proteins and protein binders such as nanobodies for drug discovery. The company serves pharmaceutical and biologics researchers, combining generative machine-learning models with wet-lab protein expression and characterization.

4 investors

Orderly Health uses AI and machine learning to process provider roster updates and maintain a centralized provider directory, improving the accuracy and reliability of healthcare provider data. It serves healthcare providers, payers, and health technology companies for uses such as regulatory compliance, patient access, and market intelligence.

4 investors

Ordio is a workforce management platform for shift-based businesses, combining AI-assisted shift scheduling, time tracking, absence management, payroll data, and digital personnel files in one system. It targets operations with rotating shifts, branches, or distributed teams such as hospitality, retail, production, and service providers.

4 investors

Origin provides operational intelligence and observability for an organization's AI agent workforce, continuously discovering every AI agent and MCP server across endpoints and attributing each action—prompts, tools invoked, files changed, and API calls—to the user and agent responsible. It also clusters AI conversations by topic, team, and initiative to make AI spend traceable for the people who approved it.

4 investors

Orkes offers a managed, enterprise version of Conductor (an open-source workflow orchestration engine), adding availability guarantees, security and access controls, audit logging, a visual workflow builder, and AI/LLM chaining. It targets engineering teams that need to run and scale workflow orchestration on cloud or private cloud without maintaining the engine themselves.

4 investors

Orq.ai provides an AI gateway that routes and governs an organization's calls to 500+ AI models across 30+ providers through a single API, adding access controls, guardrails, cost attribution, budget caps, and audit trails. It targets AI teams in regulated industries and emphasizes EU data residency and air-gapped, sovereign deployment options.

4 investors

Orthogonal provides infrastructure that enables AI agents to discover, call, and pay for third-party services and APIs through a single integration, eliminating manual setup of integrations, keys, contracts, and billing. The platform connects verified providers across data, web access, and other services, catering to developers building AI agent applications.

4 investors

Ossus builds software for managing library operations, including cataloging, circulation, and inventory management, with AI-assisted features that automate routine administrative tasks while preserving librarian judgment. The platform serves public libraries and school libraries as a complete system or as add-on agents to existing infrastructure.

4 investors

Ostro (Veeva Ostro) offers an AI-driven omnichannel engagement platform for biopharmaceutical, medical device, digital therapeutic, and diagnostics companies to deliver compliant, personalized content and experiences to healthcare providers and patients. Its solutions connect email, HCP sites, and patient sites for regulated pharmaceutical and healthcare marketing.

4 investors

Otera builds an agentic AI platform that automates complex manual workflows across enterprise systems, addressing inefficiencies in the global enterprise software market. The platform targets enterprise customers seeking to reduce operational friction between disconnected applications.

4 investors

Othersphere provides location analysis and optimization software for deploying energy-intensive infrastructure, helping teams identify ideal sites faster and with greater confidence. The company serves energy infrastructure developers and enterprises globally, emerging from Bill Gates' Breakthrough Energy.

4 investors

OTIV develops assisted, remote-control, and autonomous technology for rail freight operations to improve safety and efficiency while reducing carbon emissions and congestion. The company targets freight transportation operators seeking modal shift solutions from road to rail.

4 investors

Outverse provides AI agents for customer service automation in payments and fintech, enabling companies to handle support inquiries across channels without requiring significant system rebuilds.

4 investors

An open science laboratory focused on developing world models through decentralized research and collaboration across diverse perspectives.

4 investors

Owl AI develops image sensing technology, with expertise spanning low-noise imaging, data converters, and hardware DSP for applications in the automotive, consumer electronics, and defense markets.

4 investors

Oxipital AI builds AI-based machine vision technology, including its V-CORTX platform, cameras, and no-code dashboards, for inspection and vision-guided robotics applications. It targets machine builders and manufacturers, with a focus on food, agriculture, and other high-variability production environments.

4 investors

Oyster builds AI software for the insurance industry that connects customers, agencies, and carriers through an operating system featuring integrated digital workers that autonomously handle tasks across the insurance value chain.

4 investors