Advanced Manufacturing Startups

ZSCC designs AI silicon chips (XPU) optimized for energy efficiency in machine learning inference and training, targeting the infrastructure demands of recursive self-improvement and advanced AI systems. The company is developing both individual processor units and clustered systems for scientific discovery and model training applications.

5 investors

Zohr provides mobile tire replacement and repair services that come directly to customers at their location. The company serves vehicle owners who want a faster and more convenient alternative to traditional tire shops.

5 investors

ZwitterCo develops zwitterionic anti-fouling membranes that resist organic fouling for filtration of industrial wastewater and process streams. Its products serve dairy and food & beverage processors, biotechnology companies, grain processing/biorefining, and landfill leachate treatment for water reuse and product recovery.

5 investors

LexxPluss develops autonomous mobile robots and infrastructure systems that enable industrial equipment at factories and logistics hubs to operate independently without human direction. The company addresses labor shortages and productivity challenges in manufacturing and logistics.

4 investors

3DOS is a peer-to-peer 3D printing and manufacturing network that enables users to upload designs, earn royalties, and produce products on demand globally. The platform connects designers, brands, and creators with a distributed network of 3D printer owners for decentralized manufacturing.

4 investors

3YOURMIND provides software for on-demand manufacturing, including AI-powered part identification and manufacturing intelligence tools that automate ordering and part production. It serves enterprises and small to medium businesses aiming to build decentralized, distributed manufacturing supply chains.

4 investors

6K uses microwave plasma technology (Unimelt) to produce engineered materials, including battery cathode materials and metal powders for additive manufacturing, with an emphasis on sustainable processes. It serves industries such as additive manufacturing, renewable energy, aerospace, and consumer electronics, operating innovation labs in Massachusetts and a production facility in Pennsylvania.

4 investors

Adept Materials develops a moisture-control material technology that provides directional vapor control, humidity regulation, and temperature management, applied as coatings, films, and overlays. Spun out of a Brown University physics lab, its technology targets buildings, apparel, packaging, and healthcare applications with a focus on durability and energy efficiency.

4 investors

AeroShield is a materials science company that developed an ultra-clear silica aerogel, originating from research at MIT, aimed at improving the energy efficiency of buildings. It targets the building materials industry with insulation technology for the built environment.

4 investors

Aetos Imaging provides a visual management software built on digital scans of a customer's physical facility, used to manage, maintain, and train around building operations and assets. It serves energy and utilities, manufacturing, and other industrial and built-environment organizations.

4 investors

Megarobo (镁伽科技) develops autonomous agents and multi-agent solutions combining AI and robotic automation for smart laboratories and intelligent manufacturing. Its modular hardware and software systems serve industries including life sciences, chemicals, food and beverage, agriculture, consumer integrated circuits, and new energy, primarily in China.

4 investors

AICA develops a software system that combines AI algorithms with real-time, sensor-driven adaptive control to simplify the programming and deployment of industrial robots for manufacturers. Its technology supports applications such as precision polishing, automated screwing, EV battery disassembly, and bi-manual handling, and is used by companies including Schaeffler.

4 investors

Almetra builds AI for manufacturing by combining computer vision, sensor data, and manufacturing expertise to help industrial teams understand production processes, identify bottlenecks, and improve operations. It serves manufacturers as an intelligence layer for factories and next-generation robotics, integrating with PLC and MES systems for line monitoring and process analytics.</parameter> <parameter name="founders">[{"full_name": "Max Fischer", "title": "Co-founder & CEO"}]

4 investors

Altrove uses physics-based AI and lab automation to design and manufacture substitutes for critical inorganic materials, aiming to develop alternatives faster than conventional R&D. It targets global industrials seeking to replace critical materials that pose supply chain, cost, and regulatory risks.

4 investors

AMCA operates a software-enabled contract manufacturing facility that combines traditional and additive manufacturing with AI-powered simulation tools for product design and engineering feedback. The company serves customers requiring high-assurance manufacturing, testing, and validation capabilities, particularly those needing DO and MIL-STD qualification.

4 investors

Amper is a production monitoring and intelligence platform that uses IoT sensors to automatically track machines, operators, and jobs in real time and integrates with ERP and MES systems. It serves manufacturers—including job shops, OEMs, and contract manufacturers—to identify hidden capacity, reduce downtime and rework, and improve production planning.

4 investors

Antheia uses a yeast-based biosynthesis and fermentation platform to manufacture Key Starting Materials (KSMs) and Active Pharmaceutical Ingredients (APIs) for essential medicines, offering an alternative to fragile agricultural sourcing. The company targets pharmaceutical supply chains, aiming to reduce drug shortages and improve reliability for medicines traditionally derived from plants.

4 investors

Aras provides product lifecycle management (PLM) software for engineering and manufacturing organizations to manage product design, configuration, and data across their operations.

4 investors

Arka makes custom, eco-friendly corrugated shipping boxes and packaging for businesses across industries such as beauty, apparel, and consumer goods, with an online 3D design studio and instant proofs. Its products use FSC-certified paper and are manufactured in the USA.

4 investors

Assetflo builds IoT solutions that provide businesses with real-time visibility into the location and condition of their assets, inventory, and equipment. It serves logistics, transportation, and construction companies needing large-scale asset tracking.

4 investors

Atmo develops AI-powered weather forecasting models that process real-time satellite, ground station, radar, and ocean buoy data to deliver forecasts at high resolution and speed. The company serves governments, militaries, and industries with improved weather prediction accuracy and detail for operational decision-making.

4 investors

Atomscale builds AI models and a platform for atomic-scale materials manufacturing, capturing and analyzing process data to give real-time visibility, predict material properties, and apply adaptive process control. It serves semiconductor/materials fabrication organizations, data teams, and process engineers with domain-specific AI agents for improving yields and scale-up.

4 investors

Atum Works develops scalable 3D lithography technology capable of printing metal structures with submicron resolution for advanced manufacturing applications.

4 investors

AutoNeura develops patent-protected control software that enables transient and real-world testing on absorbing dynamometers for powertrain development. The software reduces testing costs by over 50% while maintaining homologation-grade accuracy, serving automotive test facilities and powertrain engineers across automotive and marine sectors.

4 investors