Who founded One Codex?

One Codex was founded by Nick Greenfield in 2014.

Who are One Codex's investors?

One Codex's investors include DCVC (Data Collective), Healthy Ventures, Mount Pleasant Ventures, Y Combinator, HealthX Ventures, Palm Drive Capital.

Where is One Codex headquartered?

One Codex is headquartered in Boston, US.

One Codex

AcquiredYC S14

Boston, US · Founded 2014 · 16 employees · 6 known investors

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One Codex provides microbiome sequencing data analysis and reporting software for academic labs, biotechnology companies, and clinical laboratories. The platform uses advanced algorithms and a curated database to analyze metagenomic samples with a web-based interface accessible to both bench scientists and computational biologists.

Also known as Reference Genomics, inc

Biotech Data & Infrastructure Healthtech Diagnostics GenomicsUnited States of AmericaAmerica / CanadaPartly Remote

Founders & leadership· Y Combinator alumni (S14)

One Codex was founded in 2014 by Nick Greenfield.

Nick Greenfield Founder + Board ChairNick Greenfield founded One Codex, a microbial genomics data platform acquired by Invitae in 2021 and later repurchased by employees in 2022. He previously served as VP of Product and Technology for Biosecurity at Ginkgo Bioworks and has a background in management consulting alongside software and data engineering.

Brett Camarda

Vincent ProuilletEngineering

Nik KrummScience Consultant2014–2015

Investors · 6

DCVC (Data Collective)listed by DCVC (Data Collective)Palo Alto · $5M – $25M

How we know: DCVC (Data Collective)'s portfolio page · open dataset · 5k.vc investor directory · Y Combinator's founder network · Not right? Tell us

Healthy Ventureslisted by Healthy VenturesMill Valley · $1M – $3M

How we know: the VCSheet dataset · Not right? Tell us

Mount Pleasant Ventureslisted by Mount Pleasant VenturesWashington

How we know: Mount Pleasant Ventures's portfolio page · Not right? Tell us

Y Combinatorlisted by Y CombinatorSan Francisco · $500K

How we know: the Y Combinator directory · open dataset · 5k.vc investor directory · Not right? Tell us

HealthX VenturesreportedMadison

How we know: Y Combinator's founder network · Not right? Tell us

Palm Drive CapitalreportedNew York · $500K – $5M

How we know: Y Combinator's founder network · Not right? Tell us

Related companies · 7

OpenBiomeOpenBiome Foundation advances microbiome-targeted therapies for serious conditions like Clostridioides difficile through partnerships, innovation funding, and open-access research tools. The organization works to expand patient access to microbiome treatments while accelerating scientific discovery in the field.

Luminist LabsLuminist Labs provided a non-invasive test to identify and assess the progression of liver fibrosis and NASH in patients. The company was acquired by DiscernDx in 2020.

BillionToOneBillionToOne is a precision diagnostics company that uses molecular counting technology to develop non-invasive prenatal screening and liquid biopsy tests for early disease detection. The company focuses on making molecular diagnostics accurate, fast, and accessible to patients.

GamgeeGAMGEE develops personalised mRNA cancer vaccines for dogs, created from the animal's own tumour tissue to help its immune system fight the cancer. The company manages the full process end to end—from diagnosis and tissue sampling with the pet owner's vet, to genomic analysis and treatment delivery via veterinary oncologists—and is currently running clinical trials in Australia while accepting applications globally.

Ochre BioOchre Bio develops RNA therapeutics and drug discovery platforms targeting liver disease, combining proprietary human liver datasets with AI-driven causal prediction and human tissue validation models. The company aims to address the global shortage of liver transplants by developing new treatment options for liver fibrosis and cirrhosis.

FiveableFiveable provides AI-powered exam preparation for AP classes, offering practice questions with automated scoring and personalized study tools for high school students.

LumenLumen Learning provides courseware and teaching tools built on open educational resources (OER) for higher education, aimed at faculty and students. Its products support course delivery, faculty professional development, and student-centered learning in colleges and universities.

Companies working in the same space as One Codex.

Legal entities · 1

corporate structure

Reference Genomics, inc

Frequently asked questions

What does One Codex do?: One Codex provides microbiome sequencing data analysis and reporting software for academic labs, biotechnology companies, and clinical laboratories. The platform uses advanced algorithms and a curated database to analyze metagenomic samples with a web-based interface accessible to both bench scientists and computational biologists.
Who founded One Codex?: One Codex was founded by Nick Greenfield in 2014.
Who are One Codex's investors?: One Codex's investors include DCVC (Data Collective), Healthy Ventures, Mount Pleasant Ventures, Y Combinator, HealthX Ventures, Palm Drive Capital.
Where is One Codex headquartered?: One Codex is headquartered in Boston, US.