System.One
Venture capitalPre-SeedβSeed Β· 1 people tracked
Investment thesis
System.One focuses on backing exceptional founders at the inception stage, providing early capital with conviction and strong alignment. The firm positions itself against the broader institutionalization of venture capital, which it sees as obscuring the human element central to entrepreneurial success. It intentionally stays lean, working closely with a small number of deeply engaged commitments and maintaining a concentrated portfolio to preserve trust, alignment, and meaningful engagement with founders during the earliest and riskiest phase of building new technology companies.
Source: firm website, verified Aug 3, 2026.
Team Β· 1 people
from the firm's websiteWhat they invest in
from 2 of 2 portfolio companiesAI & Machine Learning Γ2Biotech Γ1Deep Tech Γ1Logistics & Supply Chain Γ1Mobility & Transportation Γ1Robotics Γ1
HQs:United StatesΓ1
Investments Β· 2 tracked
founders shown can be your intro path
Vay develops remote driving technology that lets a human operator drive a vehicle from a distance without anyone inside, enabling services such as car sharing, fleet logistics, last-mile delivery, and public transport.
AI & Machine LearningLogistics & Supply ChainMobility & TransportationRoboticsLas Vegas, US
Thomas von der Ohe(Co-Founder & CEO)Fabrizio Scelsi(Co-Founder & CTO)Bogdan Djukic(Co-Founder, VP Engineering & Remote Driving Experience)
LabGenius develops EVA, an automated discovery engine for identifying and co-optimizing complex therapeutic antibodies such as multispecifics across multiple properties.
AI & Machine LearningBiotechDeep TechLondon
Harrison Rickerby(Executive Officer, Director)
BoardJames Field(Executive Officer, Director)
Frequently asked questions
- What stage does System.One invest at?
- System.One invests at the Pre-Seed, Seed stages.
- What sectors does System.One focus on?
- System.One focuses on Sector Agnostic.
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