Region Cuatro
Venture capitalCalifornia · Pre-Seed–Seed
Investment thesis
Region Cuatro backs sharp early-stage founders building with speed, grit and product obsession. The team consists of engineers, product builders, managers, technical leaders and repeat founders who embed with startups from the earliest days. Their focus is on AI-native, lean teams that use technology to remove friction and scale efficiently. Based in California with networks across Europe, Asia, and the Americas, the firm brings a global perspective and is deeply embedded in the Latin American startup ecosystem and Silicon Valley. They believe smaller funds outperform by staying close to founders, moving quickly, and making bold early bets.
Source: firm website, verified Aug 3, 2026.
What they invest in
from 8 of 12 portfolio companiesFintech ×3SaaS ×3Advanced Manufacturing ×2E-commerce ×2Enterprise Software ×2Hardware ×2Robotics ×2AgTech ×1
HQs:United States×4Mexico×3Colombia×1Panama×1
Investments · 12 tracked
founders shown can be your intro path
Leadsales is a CRM platform that centralizes customer conversations from WhatsApp, Facebook, and Instagram in a single interface, enabling sales teams to manage leads, automate follow-ups, and organize sales processes.
Marketing TechSaaSSales Tech
Roby Peñacastro
Breakout company in Region Cuatro's angel investing track record
Rappi is a delivery and logistics platform that connects merchants and delivery partners with millions of users across multiple countries in Latin America, offering immediate delivery services and payment opportunities for couriers.
ConsumerE-commerceFintechFoodTechLogistics & Supply ChainMarketplacesBogotá, CO
Simon Borrero(Founder/CEO)inSebastian Mejia(Founder)inFelipe Villamarin(Founder)in
Red Barn Robotics develops autonomous weeding robots for farms to eliminate intra-row weeds without human intervention, reducing labor costs and protecting soil health.
Advanced ManufacturingAgTechHardwareRoboticsSeattle, US
Adam Iseman(Founder)inIlya Kelner(Founder)inAlex Neff(Founder)in
Riveter is a web data extraction and automation platform that searches, navigates, and retrieves specific information from the internet for teams across e-commerce, marketing, real estate, and other data-dependent industries.
AI & Machine LearningData & InfrastructureDeveloper ToolsE-commerceEnterprise SoftwareSaaSSan Francisco, US
Abigail Grills(CEO & Co-founder)inHope Cochran(Director)Amy Nelson(Executive Officer, Director)
Terapify is an online mental health platform that connects users with licensed psychologists for individual and couple therapy sessions, along with supplementary wellness content such as yoga classes and guided meditations.
HealthtechMental HealthWellness & FitnessMexico City, MX
Juan Daniel Velez Santiago(Founder)inEduardo Velez Santiago(Founder)in
Toku provides software for Latin American businesses to manage accounts receivable operations, including payment processing, retry logic for failed transactions, and customer notifications, allowing companies to improve cash collection efficiency.
Enterprise SoftwareFintechSaaSMexico City, MX
Francisca Noguera(Founder)inCristina Etcheberry(Founder)inEnzo Tamburini(Founder)in
Frequently asked questions
- What stage does Region Cuatro invest at?
- Region Cuatro invests at the Pre-Seed, Seed stages.
- What sectors does Region Cuatro focus on?
- Region Cuatro focuses on AI & Machine Learning, Impact & Social Good, Sector Agnostic.
- Where is Region Cuatro located?
- Region Cuatro is headquartered in California, US.
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