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item

San Francisco, US · Founded 2024 · 6 employees · Hiring · 8 known investors

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Item is an AI-native CRM designed to replace traditional customer relationship management systems, built for high-growth companies and teams in go-to-market operations. The platform integrates data from over 100 tools and enables autonomous AI agents to execute sales, support, and success workflows while keeping teams organized with familiar interfaces.

Also known as New Item, Co.

AI & Machine Learning Enterprise Software SaaS Sales Tech B2B CRM Automation AI AssistantUnited States of AmericaAmerica / Canada

Founders & leadership· Y Combinator alumni (F25)

item was founded in 2024 by Andres Santanilla and Akshay Guthal.

AS

Andres Santanilla

Andres Santanilla CEOAndres Santanilla is a repeat founder working on a CRM successor product.

AG

Akshay Guthal

Akshay Guthal CTOFounder of Item, an AI-native CRM platform for go-to-market teams. Prior background information not provided in the self-written profile.

Investors · 8

Pioneerlisted by PioneerToronto, Ontario

How we know: Y Combinator's founder network · pioneerfund.vc · Not right? Tell us

True Ventureslisted by True VenturesSan Francisco · $500K – $3M

How we know: Y Combinator's founder network · trueventures.com · Not right? Tell us

Y Combinatorlisted by Y CombinatorSan Francisco · $500K

How we know: the Y Combinator directory · open dataset · 5k.vc investor directory · Not right? Tell us

468 CapitalreportedBerlin

How we know: Y Combinator's founder network · Not right? Tell us

MatrixreportedSan Francisco · $100K – $10M

How we know: Y Combinator's founder network · Not right? Tell us

Region CuatroreportedCalifornia

How we know: Y Combinator's founder network · Not right? Tell us

Spot VCreportedNewark

How we know: Y Combinator's founder network · Not right? Tell us

Transpose Platform ManagementreportedSan Francisco

How we know: Y Combinator's founder network · Not right? Tell us

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DryMergeDryMerge provides AI agents that automatically capture customer interaction data from email, calendar, calls, and messaging tools, updating CRM systems like Salesforce and HubSpot without manual data entry. The platform serves sales teams, asset managers, and business operations teams across industries.

Dench.comA CRM platform that deploys AI agents to handle business tasks like lead intake, email drafting, outbound sales, and report generation, which operate within communication channels and require user approval before execution.

Obento HealthObento offers a health-focused experience, though specific details about its service model, customer type, and industry positioning are not clearly stated on the visible page content.

Companies working in the same space as item.

Legal entities · 1

corporate structure

New Item, Co.

In the news

item: The AI-Native CRM that works for youycombinator.com · Nov 2025

Frequently asked questions

What does item do?: Item is an AI-native CRM designed to replace traditional customer relationship management systems, built for high-growth companies and teams in go-to-market operations. The platform integrates data from over 100 tools and enables autonomous AI agents to execute sales, support, and success workflows while keeping teams organized with familiar interfaces.
Who founded item?: item was founded by Andres Santanilla, Akshay Guthal in 2024.
Who are item's investors?: item's investors include Pioneer, True Ventures, Y Combinator, 468 Capital, Matrix, Region Cuatro, Spot VC, Transpose Platform Management.
Where is item headquartered?: item is headquartered in San Francisco, US.