San Francisco · Pre-Seed–Seed
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Investment thesis
OnePiece Labs runs a web3 accelerator and incubator supporting early-stage founders building at the frontier of AI, real-world assets, and next-generation web3 infrastructure and applications. Through partner-themed cohorts (with players such as Solana, 0G, and Camp Network), it connects founders to Layer 1 networks, exchanges, market makers, mentors, and investors to reduce time-to-market. The program does not directly fund startups but facilitates grant support from co-hosts and access to an investor network, alongside daily founder support, expert mentorship, an offline SF Bay Area community, demo days, and an active alumni network spanning both its venture fund and incubator graduates.
Source: firm website, verified Aug 7, 2026.
What they invest in
from 13 of 18 portfolio companiesCrypto & Web3 ×11Data & Infrastructure ×6AI & Machine Learning ×4Fintech ×4Consumer ×2Social ×2Cloud Computing ×1Creator Economy ×1
HQs:United States×4China×1
Who they back
founder profiles across 9 portfolio companiesFounding team size:solo founder×32 founders×44+ founders×2
Portfolio companies · 18 tracked
alumni founders can tell you what the program is really likeFog Works develops personal AI edge computing solutions, combining software and hardware, that allow users to run AI assistants locally while maintaining data sovereignty through a decentralized storage network.
AI & Machine LearningCrypto & Web3Data & InfrastructureHardwareIoT
Xinglu Lin(CEO & Co-Founder)Victor Chen(COO)Zhicong Liu(Chief Engineer)Felicia DengWilliam Entriken(Chief Architect)
Co-investorsAlumni VenturesIoTeXProtagonistSolana FoundationDraper Dragon
The Algorand Foundation supports and grows the Algorand blockchain ecosystem by improving the developer experience, contributing to core protocol infrastructure and standards, and enabling decentralized governance.
Crypto & Web3Deep TechDeveloper ToolsFintechQuantum Computing
Silvio Micali(Founder)inSteven Kokinos(Founder)
Co-investorsAlumni VenturesAndromeda CapitalArrington CapitalBasecamp FundBig Candle CapitalBixin Capital+27 more
Aspecta is a blockchain protocol and infrastructure that standardizes illiquid assets (such as pre-TGE shares, locked tokens, private equities, and RWAs) into ERC-20 credentials for on-chain price discovery and trading.
Crypto & Web3Data & InfrastructureFintech
Co-investorsGeekCartelTaisu VenturesUpHonest Capital
Camp Network is a Layer-1 blockchain for intellectual property infrastructure, providing a global IP registry that lets users own and monetize their IP and enables AI agents to train on user-owned IP.
AI & Machine LearningCrypto & Web3Data & Infrastructure
James Chi(Founder)inNirav Murthy(Founder)in
Co-investors1k(x)1kxBlockchain CapitalEterna CapitalHTX Ventures (ex Huobi Ventures)Hyperithm+12 more
Merlin Chain is a Bitcoin Layer 2 network that is EVM-compatible and uses ZK-Rollup technology, supporting Bitcoin protocols such as BRC20, BRC420, Bitmap, Atomicals, Pipe, and Stamp.
Crypto & Web3Data & Infrastructure
Co-investorsAlphaLab CapitalCaladanGenerative VenturesStratified CapitalKuCoin Labs
NEAR is an open blockchain infrastructure powering the agent economy, providing cross-chain execution, confidential settlement, and private inference capabilities.
AI & Machine LearningCloud ComputingCrypto & Web3Miami, US
Illia Polosukhin(Founder)inAlexander Skidanov(Founder)
Co-investors0 VenturesA.Capital Venturesa16z cryptoAccompliceAdvanced BlockchainAmbush Capital+42 more
OffChain Global is a Web3 professional community with chapters in seventy cities, hosting virtual and in-person events such as meetups, panels, and conferences.
Crypto & Web3Social
Polina(Early founder)
Co-investorsPantera CapitalStone Bridge VenturesStonebridge Ventures
0G (Zero Gravity) is a blockchain infrastructure stack for AI applications, combining an EVM-compatible Layer 1 chain, a distributed storage network, a compute network, and a scalable data availability layer.
AI & Machine LearningCrypto & Web3Data & Infrastructure
Ming Wu(Founder)inMichael Heinrich(Founder)inAda Heinrich(Founder)Arne Hartmann(Founder)Fan Long(Founder)Thomas Yao(Founder)
Co-investorsAbstract VenturesAlphaLab CapitalAnimoca BrandsBaseTwoBlockchain BuildersCaladan+17 more
OKX is a cryptocurrency exchange platform that enables trading and custody of digital assets secured by blockchain technology.
Crypto & Web3Fintech
Star Xu(Founder)inRoshan Robertin
Co-investorsBitDAOCircle VenturesMantle NetworkIntercontinental Exchange
Sei is a high-performance EVM Layer 1 blockchain built for trading and digital asset markets, featuring onchain order books and the Autobahn multi-proposer consensus mechanism.
Crypto & Web3Data & InfrastructureFintechSan Francisco, US
Jayendra Jog(Founder)inJeffrey Feng(Founder)
Co-investorsAsymmetricBixin CapitalBixin VenturesCogitent VenturesCVP NoLimitFJ Labs+9 more
Telegram is a cross-platform messaging application with encrypted, self-destructing messages, multi-device sync, and large group chats.
ConsumerMedia & EntertainmentSocial
Co-investorsAfford.CapitalAlphabit FundAngelONE CapitalArchetypeArrington CapitalBitDAO+48 more
Upland is a location-based metaverse game where players own and develop digital properties mapped to real-world addresses across fifty+ cities, with an in-game economy that clears in real dollars.
ConsumerCrypto & Web3GamingSan Francisco, US
Dirk(Co-Founder)Idan(Co-Founder)Dirk Lueth(Founder)inIdan Zuckerman(Founder)inMani Honigstein(Founder)
Co-investorsBlock.oneAlumni VenturesCrit VenturesGaingelsRed Beard VenturesTransform Ventures+4 more
Other
Tracked investments with no reachable website or further public details — typically companies that wound down, renamed, or were absorbed.
AlternativesbyftBatchForesight VenturesLibation LabsSequoiacap
Portfolio news
latest coverage across their companiesOKX · investing.com · Aug 21, 2026
Frequently asked questions
- How many investments has OnePiece Labs made?
- OnePiece Labs has 18 tracked investments.
- What stage does OnePiece Labs invest at?
- OnePiece Labs invests at the Pre-Seed, Seed stages.
- What sectors does OnePiece Labs focus on?
- OnePiece Labs focuses on AI & Machine Learning, Consumer, Crypto & Web3, Deep Tech, Social.
- Where is OnePiece Labs located?
- OnePiece Labs is headquartered in San Francisco, US.
- Who does OnePiece Labs co-invest with?
- OnePiece Labs most often shares deals with Eterna Capital, Dragonfly, Generative Ventures, among 111 tracked co-investors.
Media · Podcasts & interviews
from their channelOnePiece Labs × Solana Accelerator Demo Day
OnePiece Labs Web3 Talks
ENTREPRENEURSHIP 201: Token Listing 101
OnePiece Labs Web3 Talks
ENTREPRENEURSHIP 201: Post Listing Momentum
OnePiece Labs Web3 Talks
ENTREPRENEURSHIP 201: Pitching Materials Deck, Blurb, Data room
OnePiece Labs Web3 Talks
ENTREPRENEURSHIP 101: Pitfalls in Web3 Go-To-Market
OnePiece Labs Web3 Talks
ENTREPRENEURSHIP 101: Growth Strategy, Incentives and User Activation
OnePiece Labs Web3 Talks
Images
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