San Francisco Β· Pre-SeedβSeed
Investment thesis
OnePiece Labs runs a web3 accelerator and incubator supporting early-stage founders building at the frontier of AI, real-world assets, and next-generation web3 infrastructure and applications. Through partner-themed cohorts (with players such as Solana, 0G, and Camp Network), it connects founders to Layer 1 networks, exchanges, market makers, mentors, and investors to reduce time-to-market. The program does not directly fund startups but facilitates grant support from co-hosts and access to an investor network, alongside daily founder support, expert mentorship, an offline SF Bay Area community, demo days, and an active alumni network spanning both its venture fund and incubator graduates.
Source: firm website, verified Aug 7, 2026.
What they invest in
from 15 of 20 portfolio companiesCrypto & Web3 Γ10Data & Infrastructure Γ5Fintech Γ4AI & Machine Learning Γ3Consumer Γ2SaaS Γ2Social Γ2Cloud Computing Γ1
Portfolio companies Β· 20 tracked
alumni founders can tell you what the program is really like
Algorand is a blockchain platform offering institutional-grade infrastructure for decentralized finance, agentic commerce, and real-world asset tokenization with quantum-resistant cryptography and instant transaction finality.
Crypto & Web3FintechQuantum Computing
Silvio Micali(Founder)in
Co-investorsAlumni VenturesAndromeda CapitalArrington CapitalBasecamp FundBig Candle CapitalBixin Capital+15 more
Aspecta is a blockchain protocol and infrastructure that standardizes illiquid assets (such as pre-TGE shares, locked tokens, private equities, and RWAs) into ERC-20 credentials for on-chain price discovery and trading.
Crypto & Web3Data & InfrastructureFintech
Co-investorsUpHonest Capital
Camp Network is a Layer-1 blockchain for intellectual property infrastructure, providing a global IP registry that lets users own and monetize their IP and enables AI agents to train on user-owned IP.
AI & Machine LearningCrypto & Web3Data & Infrastructure
Co-investors1k(x)1kxBlockchain CapitalEterna CapitalHyperithmMarin Digital Ventures+5 more
Luma provides a platform for creating event pages, sending invitations, and selling tickets for events.
SaaS
Victor Pontis(Founder)in
Co-investorsAllen Institute for AI (AI2) IncubatorAmplify PartnersBerkley Center for EntrepreneurshipBethnal Green VenturesCedar CapitalEIT Urban Mobility Accelerator+13 more
Merlin Chain is a Bitcoin Layer 2 network that is EVM-compatible and uses ZK-Rollup technology, supporting Bitcoin protocols such as BRC20, BRC420, Bitmap, Atomicals, Pipe, and Stamp.
Crypto & Web3Data & Infrastructure
Co-investorsAlphaLab CapitalCaladanGenerative VenturesKuCoin Labs
Harvard Alumni Entrepreneurs (HAE) is a non-profit organization for Harvard University alumni across its 13 schools, offering founder-focused programs including an alumni-only, equity-free virtual accelerator, an academy, and mentorship and access pathways.
EdTechImpact & Social Good
Startup that went through the OnePiece Labs accelerator; founder cites connections, daily support, community and mentorship.
lu.ma is a platform for creating event pages, inviting attendees, and selling tickets for events.
Marketplaces
Victor Pontis(Founder)inDan Liu(Founder)
Co-investorsAir Street CapitalAtelierBonfire VenturesExceptional CapitalFirst Bight VenturesIOSG Ventures+11 more
NEAR is an open blockchain infrastructure powering the agent economy, providing cross-chain execution, confidential settlement, and private inference capabilities.
AI & Machine LearningCloud ComputingCrypto & Web3
Illia Polosukhin(Co-Founder)
Co-investorsA.Capital Venturesa16z cryptoAccompliceAdvanced BlockchainAmbush CapitalAmplify Partners+34 more
OffChain Global is a Web3 professional community with chapters in seventy cities, hosting virtual and in-person events such as meetups, panels, and conferences.
Crypto & Web3Social
Polina(Early founder)
0G (0G Labs) builds decentralized infrastructure for AI, including verifiable compute, private inference, and decentralized storage, aimed at developers building onchain AI and Web3 applications.
AI & Machine LearningCrypto & Web3Data & Infrastructure
Co-investorsAbstract VenturesAlphaLab CapitalAnimoca BrandsBaseTwoBlockchain BuildersCaladan+14 more
OKX is a cryptocurrency exchange offering trading with high execution speed, low fees, and APIs, aimed at both beginner and experienced traders.
Crypto & Web3Fintech
Co-investorsBitDAOMantle Network
Tally is an online form builder that works like a text document, letting users create forms by typing and inserting blocks without code.
Future of WorkMarketing TechSaaS
Co-investors1991 VenturesAnchorless BangladeshAscensionBloom / Giesen Family OfficeDay One CapitalFlori Ventures+11 more
Sei is a high-performance EVM Layer 1 blockchain built for trading and digital asset markets, featuring onchain order books and the Autobahn multi-proposer consensus mechanism.
Crypto & Web3Data & InfrastructureFintech
Co-investorsBixin CapitalBixin VenturesCogitent VenturesCVP NoLimitHyperithmHypersphere Ventures+3 more
Telegram is a cross-platform messaging application with encrypted, self-destructing messages, multi-device sync, and large group chats.
ConsumerMedia & EntertainmentSocial
Co-investorsAcquire FiAfford.CapitalAlphabit FundAngelONE CapitalArrington CapitalAsia GreenTech Fund+48 more
Upland is a free-to-play virtual property game where players ("Architects") claim, develop, and trade digital properties mapped to real-world addresses in 50+ cities, earning in-game currency (UPX) and attracting digital residents ("Uppies").
ConsumerCrypto & Web3Gaming
Co-investorsCrit VenturesRed Beard VenturesTransform Ventures
Portfolio news
latest coverage across their companiesCamp Β· yakimaherald.com Β· Aug 4, 2026
Events Β· techcrunch.com Β· Jul 14, 2026
Frequently asked questions
- How many investments has OnePiece Labs made?
- OnePiece Labs has 20 tracked investments.
- What stage does OnePiece Labs invest at?
- OnePiece Labs invests at the Pre-Seed, Seed stages.
- What sectors does OnePiece Labs focus on?
- OnePiece Labs focuses on AI & Machine Learning, Consumer, Crypto & Web3, Deep Tech, Social.
- Where is OnePiece Labs located?
- OnePiece Labs is headquartered in San Francisco, US.
- Who does OnePiece Labs co-invest with?
- OnePiece Labs most often shares deals with Amplify Partners, Dragonfly, IOSG Ventures, among 132 tracked co-investors.
Media Β· Podcasts & interviews
from their channelOnePiece Labs Γ Solana Accelerator Demo Day
OnePiece Labs Web3 Talks
ENTREPRENEURSHIP 201: Token Listing 101
OnePiece Labs Web3 Talks
ENTREPRENEURSHIP 201: Post Listing Momentum
OnePiece Labs Web3 Talks
ENTREPRENEURSHIP 201: Hiring a Legal Professional
OnePiece Labs Web3 Talks
ENTREPRENEURSHIP 201: To-VC: What are VCs Looking for, How to Approach VCs
OnePiece Labs Web3 Talks
ENTREPRENEURSHIP 201: Hiring & Compensation in Web3
OnePiece Labs Web3 Talks
Images
Similar investors
Khosla Ventures is a venture capital firm that invests in early-stage companies focused on technology, mobile, and clean energy sectors, including biotechnology applications. The firm provides capital and strategic support to entrepreneurs developing breakthrough technologies across multiple markets.
OMERS Ventures is the venture capital arm of the OMERS pension plan, investing in early-stage technology founders building solutions across North America and Europe.
MDSV Capital is a Palo Alto-based investment firm that backs top emerging manager funds and co-invests directly in high-growth 'outlier' companies emerging from their portfolios.
Everywhere Ventures is an early-stage venture firm that backs founders globally, supported by a community of founders and operators as LPs.
Hangzhou Tunlan Investment Management Co., Ltd. is a China-based professional venture capital management firm, with a management team drawn from successful entrepreneurs, Fortune 500 executives, and Alibaba Group senior management.