Fundraising Fox

Eshelman Ventures, LLCFull Portfolio

18 tracked investments · listed companies and verified rows first

Hyperion Defihyperiondefi.comNASDAQ: HYPDJul 2016SEC filingmedium confidence

Hyperion DeFi is a U.S.

BiotechCrypto & Web3FintechHealthtechLaguna Hills, US

Michael Rowe(Executive Officer, Director)Hyunsu Jung(Chief Executive Officer)CURT LABELLE(Executive Officer, Director)SHUHEI YOSHIDA(Director)BARRY BUTLER(Executive Officer)TSONTCHO IANCHULEV(Executive Officer, Director)

Board seatFred Eshelman· per SEC Form D · $8M raise · filed Aug 2016

Dignify Therapeuticsdignifytherapeutics.cominOct 2014

Dignify Therapeutics develops "on demand" drugs that trigger emptying of the bladder and/or bowel when a person chooses, aimed at restoring control of bowel and bladder function.

BiotechDigital HealthMedical DevicesResearch Triangle Park, US

Karl B Thor(Executive Officer, Director, Promoter)Edward C Burgard(Executive Officer, Director, Promoter)Benny Ward(Executive Officer, Director, Promoter)Daniel J Ricca(Director, Promoter)Ebrahim Versi(Director, Promoter)Karl Thor

Board seatFred Eshelman· per SEC Form D

Innocrin Pharmaceuticals HoldingsApr 2015SEC filingmedium confidence

BiotechDurham, US

Richard Kent(Director)Kristopher Wood(Director)Thomas Laundon(Executive Officer)S. Edward Torres(Director)Steven Weinstein(Director)William Moore(Executive Officer, Director)

Board seatFred Eshelman· per SEC Form D · $28.1M raise · filed Apr 2015

NeoantigenicsFeb 2015SEC filingmedium confidence

BiotechCharlottesville, US

Edward J. Leary(Executive Officer, Promoter)Brian A. Pollok(Executive Officer, Director, Promoter)John C. Herr(Executive Officer, Director, Promoter)

Board seatFred Eshelman· per SEC Form D · $3M raise · filed Feb 2015

Aruna Bioarunabio.com

PartnerFred Eshelman· solo GP

Auven Therapeuticsauventx.com

PartnerFred Eshelman· solo GP

Breakthru Medicinebreakthrumed.com

Breakthru Medicine is a biotech company developing a portfolio of oncology therapeutics aimed at unmet clinical needs, using platform technologies and multiple independent drug programs.

BiotechHealthtech

PartnerFred Eshelman· solo GP

Carboncarbon3d.comin

Carbon designs and manufactures 3D-printed products using advanced photopolymer resins, computational design tools, and proprietary hardware.

Advanced ManufacturingHardwareNew MaterialsRedwood City, US

James J. Goetz(Director)Joseph M. DeSimone(Executive Officer, Director)Andy Wheeler(Director)Adam Grosser(Director)Lars Steven Nelson(Director)Alan S. Mulally(Director)

PartnerFred Eshelman· solo GP

Cavalry Biosciencescavalry.bio

Cavalry Biosciences is a biopharmaceutical company focused on developing medicines that leverage the body's inherent regenerative and repair mechanisms, particularly in areas of age-related disease and tissue regeneration.

BiotechDeep TechLongevityMedical Devices

Jan van Deursen, PhD(Co-founder, Advisor)inNathaniel (Ned) David, PhD(Co-founder, Chairman)in

PartnerFred Eshelman· solo GP

Genesisgenesisbiocapital.com

PartnerFred Eshelman· solo GP

Incyclix Bioincyclixbio.comin𝕏Aug 2025

Incyclix Bio is a clinical-stage biotech company developing cell cycle control therapies that target the aberrant cell proliferation driving cancers, with a lead CDK2 inhibitor (INX-315).

BiotechHealthtechDurham, US

Patrick Roberts(Executive Officer and member of the Board of Managers.)Sid Subramony(Member of the Board of Managers.)

BoardFredric N. Eshelman(Executive Officer and member of the Board of Managers.)Norman Sharpless(Member of the Board of Managers.)

PartnerFred Eshelman· solo GP

Jupiter Bioventuresjupiter.bioin

Jupiter is a biotech company that discovers and develops new medicines across multiple therapeutic areas.

BiotechChapel Hill, US

Ned Sharpless(Co-founder & CEO)Leigh Delacy(Co-founder & Partner and COO)

PartnerFred Eshelman· solo GP

Komo Bioscienceskomobiosciences.comin

KOMO Biosciences develops genome engineering technology based on hyperactive large serine integrases to transform cell-based manufacturing of biologics and advanced therapies.

BiotechDeep Tech

Jennifer Manning(Founder & CEO)Thomas Page(Acting CTO)Matt Farabaugh(Acting CFO)Jesse B. Owens(Acting CSA)Ray Tabibiazar(Chairman of the Board)

PartnerFred Eshelman· solo GP

Med Aditusmedaditus.org

Company working with governments, international agencies, and private partners to improve access to medicine across Sub-Saharan Africa, spanning product development, manufacturing, supply chains, and patient delivery.

PartnerFred Eshelman· solo GP

Paradigm Therapeuticsparadigmtherapeutics.com

Paradigm Therapeutics is a biopharmaceutical company developing Zorblesia (SD-101), a proprietary topical whole-body therapy for treating the wounds, lesions, and infections associated with all subtypes of Epidermolysis Bullosa (EB), a rare genetic connective tissue disorder.

BiotechHealthtechMedical DevicesMt Pleasant, US

Robert Ryan(Dr.)

PartnerFred Eshelman· solo GP

Phoenix Molecular Designsphoenixmd.cain

Phoenix Molecular Designs develops small-molecule cancer therapeutics targeting RSK, a driver of tumor growth and metastasis.

BiotechHealthtech

PartnerFred Eshelman· solo GP

Sapience Therapeuticssapiencetherapeutics.comin

BiotechScarsdale, US

Robert Ruffolo, Ph.D.(Director)David Scheinberg, Ph.D.(Director)Isaac Blech(Director)Barry Kappel, Ph.D.(Executive Officer, Director)

PartnerFred Eshelman· solo GP

Wilmington Design Co.wilmingtondesignco.com

Wilmington Design Company (WDC) is a full-service marketing agency offering custom website design and development, brand identity and logo design, SEO, paid advertising, and digital marketing strategy for small businesses.

AdTechMarketing TechWilmington, US

PartnerFred Eshelman· solo GP

Rows marked “SEC filing” are inferred from directors named on the company's SEC Form D — public regulatory data, not a portfolio list published by the firm.